Recombinant Human SLC2A1 protein, His & SUMO-tagged

• Cat.No.: SLC2A1-1753H
• Product Overview: Recombinant Human SLC2A1 aa. (Phe409~Asp489) fused with N-terminal His & SUMO tag was produced in E. coli cells.

Specification

• Description: This gene encodes a major glucose transporter in the mammalian blood-brain barrier. The encoded protein is found primarily in the cell membrane and on the cell surface, where it can also function as a receptor for human T-cell leukemia virus (HTLV) I and II. Mutations in this gene have been found in a family with paroxysmal exertion-induced dyskinesia.
• Source: E. coli
• Species: Human
• Tag: His & SUMO
• Form: Freeze-dried powder
• Molecular Mass: 20kDa as determined by SDS-PAGE reducing conditions.
• Protein length: Phe409~Asp489
• Endotoxin: <1.0EU per 1ug (determined by the LAL method)
• Purity: >95%
• Applications: SDS-PAGE; WB; ELISA; IP; CoIP; Reporter Assays; Purification; Amine Reactive Labeling.
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
• Concentration: 200μg/mL
• Storage buffer: 20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% sarcosyl, 5%Trehalose and Proclin300.
• Reconstitution: Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex.
• Isoelectric Point: 4.8

Gene Information

• Gene Name: SLC2A1 solute carrier family 2 member 1 [ Homo sapiens (human) ]
• Official Symbol: SLC2A1
• Synonyms: SLC2A1; solute carrier family 2 member 1; CSE; PED; DYT9; GLUT; DYT17; DYT18; EIG12; GLUT1; HTLVR; GLUT-1; SDCHCN; GLUT1DS; solute carrier family 2, facilitated glucose transporter member 1; choreoathetosis/spasticity, episodic (paroxysmal choreoathetosis/spasticity); glucose transporter type 1, erythrocyte/brain; hepG2 glucose transporter; human T-cell leukemia virus (I and II) receptor; receptor for HTLV-1 and HTLV-2; solute carrier family 2 (facilitated glucose transporter), member 1
• Gene ID: 6513
• mRNA Refseq: NM_006516.2
• Protein Refseq: NP_006507.2
• UniProt ID: P11166