snx1
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  • Official Full Name
  • sorting nexin 1
  • Background
  • This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This endosomal protein regulates the cell-surface expression of epidermal growth factor receptor. This protein also has a role in sorting protease-activated receptor-1 from early endosomes to lysosomes. This protein may form oligomeric complexes with family members. This gene results in three transcript variants encoding distinct isoforms.
  • Synonyms
  • SNX1; sorting nexin 1; sorting nexin-1; HsT17379; MGC8664; SNX1A; Vps5; sorting nexin 1A
Cat.#:SNX1-2800HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Sorting Nexin 1, His-tagged
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Cat.#:SNX1-30609THTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human SNX1, His-tagged
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Cat.#:SNX1-30610THTag:T7
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human SNX1, T7 -tagged
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Cat.#:SNX1-5652RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat SNX1 Protein
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Cat.#:SNX1-953CTag:His
Source (Host):Mammalian CellsSpecies:Cynomolgus Monkey
Product nameRecombinant Cynomolgus SNX1 Protein, His-tagged
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Cat.#:SNX1-4386RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey SNX1 Protein, His-tagged
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Cat.#:SNX1-2991HTag:T7
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Sorting Nexin 1, T7-tagged
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Cat.#:SNX1-1605HCLTag:N/A
Source (Host):Species:Human
Product nameRecombinant Human SNX1 293 Cell Lysate
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Involved Pathway

SNX1 involved in several pathways and played different roles in them. We selected most pathways SNX1 participated on our site, such as Endocytosis, which may be useful for your reference. Also, other proteins which involved in the same pathway with SNX1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Endocytosis
ERBB4; SMURF1; KIT; HSC70; ASAP2A; STAMBPB; GRK7B; PLD2; ARPC4; PIP5K1BB

Protein Function

SNX1 has several biochemical functions, for example, epidermal growth factor receptor binding, identical protein binding, insulin receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SNX1 itself. We selected most functions SNX1 had, and list some proteins which have the same functions with SNX1. You can find most of the proteins on our site.
Function
Related Protein
Function epidermal growth factor receptor binding
Related Protein FER; TNK2; EREG; Fert2; CBLC; SNX1; HBEGFA; ATXN2; LINGO1; YES1
Function identical protein binding
Related Protein PNMA5; SELK; PTS; KCTD13; TMEM115; IGF2R; ATL2; SNCAIP; USP2; SERPINA1E
Function insulin receptor binding
Related Protein FRS2; IRS4; SNX2; IRS2; DOK5; DOK3; INS1; INS; IRS1; PTPN1
Function leptin receptor binding
Related Protein SNX2; SNX1; SNX4
Function phosphatidylinositol binding
Related Protein SNX27; MTM1; SNX27A; SNX1; SNX1B; TNFAIP8L3; PXK; NCF1; ITPR1; SNX31
Function protein binding
Related Protein SVIL; MCCC1; SMC3; HELZ; CRIPT; NABP1; POLR1A; CSPP1; MPZL3; MUSK
Function protein heterodimerization activity
Related Protein VOX; SOX8; TCF3A; DDX1; HIST2H2L; HOMER1; RXRA; ANO2; ALX4; CD3E
Function protein homodimerization activity
Related Protein PON1; CRYBB2; G6PD; CECR1; C16orf89; NUDT21; MTPAP; DMRTC1C2; SLC51A; DNM1L
Function transferrin receptor binding
Related Protein CD81; RGMA; SNX2; HFE; SNX4; Trf; SNX1; TF; HFE2

Interacting Protein

SNX1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SNX1 here. Most of them are supplied by our site. Hope this information will be useful for your research of SNX1.
ARL6IP1; SNX32; REEP6; pi3p; RTN3