stau1
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  • Official Full Name
  • staufen, RNA binding protein, homolog 1 (Drosophila)
  • Background
  • Staufen is a member of the family of double-stranded RNA (dsRNA)-binding proteins involved in the transport and/or localization of mRNAs to different subcellular compartments and/or organelles. These proteins are characterized by the presence of multiple dsRNA-binding domains which are required to bind RNAs having double-stranded secondary structures. The human homologue of staufen encoded by STAU, in addition contains a microtubule- binding domain similar to that of microtubule-associated protein 1B, and binds tubulin. The STAU gene product has been shown to be present in the cytoplasm in association with the rough endoplasmic reticulum (RER), implicating this protein in the transport of mRNA via the microtubule network to the RER, the site of translation. Five transcript variants resulting from alternative splicing of STAU gene and encoding three isoforms have been described. Three of these variants encode the same isoform, however, differ in their 5UTR.
  • Synonyms
  • STAU1; staufen, RNA binding protein, homolog 1 (Drosophila); STAU, staufen (Drosophila, RNA binding protein) , staufen, RNA binding protein (Drosophila); double-stranded RNA-binding protein Staufen homolog 1; Double stranded RNA binding protein Staufen homolog 1; Double stranded RNA binding protein Staufen homolog; FLJ25010; MGC124588; STAU; STAU1_HUMAN; staufen; Staufen RNA binding protein (Drosophila); Staufen RNA binding protein homolog 1; OTTHUMP00000031233; OTTHUMP00000031234; OTTHUMP00000031235; OTTHUMP00000031236; OTTHUMP00000031238; OTTHUMP00000031239
Cat.#:STAU1-20HTag:His
Source (Host):E.coliSpecies:Human
Product nameRecombinant Human STAU1 Protein, His-tagged
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Cat.#:STAU1-21HTag:GST
Source (Host):E.coliSpecies:Human
Product nameRecombinant Human STAU1 Protein, GST-tagged
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Cat.#:STAU1-30858THTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human STAU1, His-tagged
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Cat.#:STAU1-4520RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey STAU1 Protein, His-tagged
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Cat.#:STAU1-2056CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken STAU1
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Cat.#:STAU1-11605ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish STAU1
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Cat.#:STAU1-1414HCLTag:N/A
Source (Host):Species:Human
Product nameRecombinant Human STAU1 293 Cell Lysate
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Cat.#:STAU1-1415HCLTag:N/A
Source (Host):Species:Human
Product nameRecombinant Human STAU1 293 Cell Lysate
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Protein Function

STAU1 has several biochemical functions, for example, double-stranded RNA binding, poly(A) RNA binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by STAU1 itself. We selected most functions STAU1 had, and list some proteins which have the same functions with STAU1. You can find most of the proteins on our site.
Function
Related Protein
Function double-stranded RNA binding
Related Protein IFIH1; LSM14A; HSPD1; OASL1; MYH4; ACTN1; TLR3; OASL2; STAU2; ILF2
Function poly(A) RNA binding
Related Protein PPAN; TAF15; SARS2; ASCC3; C22orf28; HSPE1; HIST1H1D; THOC4; DDX54; SKIV2L2
Function protein binding
Related Protein MZB1; HNRNPM; SYNE1; MSX2; FBXO9; BDKRB1; EYA1; XRCC1; KIF27; FLNA
Function protein phosphatase 1 binding
Related Protein PPP1R11; PPP1R9B; SH3RF2; LILRB1; PHACTR3; STAU1; SHOC2; PHACTR3B; LILRB2; PAWR

Interacting Protein

STAU1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with STAU1 here. Most of them are supplied by our site. Hope this information will be useful for your research of STAU1.
UPF1; NS; RPLP0; NCL; RPS6; DHX9