stip1
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  • Official Full Name
  • stress-induced-phosphoprotein 1
  • Background
  • STIP1 is an adaptor protein that coordinates the functions of HSP70 (see HSPA1A; MIM 140550) and HSP90 (see HSP90AA1;;MIM 140571) in protein folding. It is thought to assist in the transfer of proteins from HSP70 to HSP90 by binding;both HSP90 and substrate-bound HSP70. STIP1 also stimulates the ATPase activity of HSP70 and inhibits the ATPase;activity of HSP90, suggesting that it regulates both the conformations and ATPase cycles of these chaperones (Song and;Masison, 2005 (PubMed 16100115)).
  • Synonyms
  • STIP1; stress-induced-phosphoprotein 1; HOP; Hsp70/Hsp90 organizing protein; STI1; NY-REN-11 antigen; Hsp70/Hsp90-organizing protein; hsc70/Hsp90-organizing protein; renal carcinoma antigen NY-REN-11; transformation-sensitive protein IEF SSP 3521; P60; STI1L; IEF-SSP-3521
Cat.#:STIP1-2964HTag:MYC/DDK
Source (Host):HEK293Species:Human
Product nameRecombinant Human STIP1 Protein, MYC/DDK-tagged
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Cat.#:STIP1-2967HTag:His
Source (Host):Insect cellsSpecies:Human
Product nameRecombinant Human STIP1 Protein, His-tagged
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Cat.#:STIP1-5520HTag:N/A
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Stress-Induced-Phosphoprotein 1
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Cat.#:STIP1-670HTag:His/GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human STIP1 Protein, His/GST-tagged
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Cat.#:STIP1-1810HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Stress-induced-phosphoprotein 1, His-tagged
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Cat.#:STIP1-251HTag:His
Source (Host):sf9 cellsSpecies:Human
Product nameRecombinant Human STIP1 Protein, His-tagged
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Cat.#:STIP1-252HTag:DDK
Source (Host):sf9 cellsSpecies:Human
Product nameRecombinant Human STIP1 Protein, DDK-tagged
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Cat.#:STIP1-3006HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human STIP1, GST-tagged
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Cat.#:STIP1-31467THTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human STIP1, His-tagged
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Cat.#:STIP1-31468THTag:
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human STIP1
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Cat.#:Stip1-127MTag:His
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Stip1 protein, His-tagged
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Cat.#:STIP1-16130MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse STIP1 Protein
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Cat.#:STIP1-5789RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat STIP1 Protein
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Cat.#:STIP1-1842ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish STIP1
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Cat.#:STIP1-641HCLTag:N/A
Source (Host):HEK293Species:Human
Product nameRecombinant Human STIP1 lysate
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Involved Pathway

STIP1 involved in several pathways and played different roles in them. We selected most pathways STIP1 participated on our site, such as Prion diseases, which may be useful for your reference. Also, other proteins which involved in the same pathway with STIP1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Prion diseases
C8G; C1QB; PRKACA; PRNP; C9; C1QA; NCAM1; FYN; BAX; IL1A

Protein Function

STIP1 has several biochemical functions, for example, Hsp70 protein binding, chaperone binding, poly(A) RNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by STIP1 itself. We selected most functions STIP1 had, and list some proteins which have the same functions with STIP1. You can find most of the proteins on our site.
Function
Related Protein
Function Hsp70 protein binding
Related Protein STUB1; BAG6; MVD; CDKN1B; L7RN6; METTL21A; PACRG; FAM119A; DNAJC10; PPEF2
Function chaperone binding
Related Protein BAX; DNAJB2; DNAJA3A; GET4; DNAJC3; HSPA5; UBL4A; TSACC; PARK2; CALR
Function poly(A) RNA binding
Related Protein PSMC1; RPS4X; LRP1; ABT1; H1FX; SART3; POLR2A; PRPF38B; RPL36; SKIV2L2
Function protein C-terminus binding
Related Protein CDC20; SIRT1; MIF4GD; PPP1R9B; ERCC4; TAX1BP3; SAE1; YEATS4; CALCOCO1; TBL1X
Function protein binding
Related Protein NMB; H3F3C; CLDN2; BTN3A1; MRPS23; TRIM2; SCO1; SPINK2; FAM154A; DDX21

Interacting Protein

STIP1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with STIP1 here. Most of them are supplied by our site. Hope this information will be useful for your research of STIP1.
HSP90AA1; NR3C1; VCAM1; EGFR; ACD; CDC37L1; CCDC117