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STIP1

  • Official Full Name

    stress-induced-phosphoprotein 1

  • Overview

    STIP1 is an adaptor protein that coordinates the functions of HSP70 (see HSPA1A; MIM 140550) and HSP90 (see HSP90AA1;;MIM 140571) in protein folding. It is thought to assist in the transfer of proteins from HSP70 to HSP90 by binding;both HSP90 and substrate-bound HSP70. STIP1 also stimulates the ATPase activity of HSP70 and inhibits the ATPase;activity of HSP90, suggesting that it regulates both the conformations and ATPase cycles of these chaperones (Song and;Masison, 2005 (PubMed 16100115)).
  • Synonyms

    STIP1; stress-induced-phosphoprotein 1; HOP; Hsp70/Hsp90 organizing protein; STI1; NY-REN-11 antigen; Hsp70/Hsp90-organizing protein; hsc70/Hsp90-organizing protein; renal carcinoma antigen NY-REN-11; transformation-sensitive protein IEF SSP 3521; P60; STI1L; IEF-SSP-3521;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Rat
  • Zebrafish
  • E. coli
  • E.coli
  • HEK293
  • HEK293T
  • Insect Cell
  • Mammalian Cell
  • Mammalian cells
  • Sf9 Insect Cell
  • DDK
  • Flag
  • GST
  • His
  • His (Fc)
  • Avi
  • His|GST
  • SUMO
  • Myc
  • Myc|DDK
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human STIP1-3006H Recombinant Human STIP1, GST-tagged E.coli GST C-term-349aa
Human STIP1-252H Recombinant Human STIP1 Protein, DDK-tagged Sf9 Insect Cell DDK
Human STIP1-251H Recombinant Human STIP1 Protein, His-tagged Sf9 Insect Cell His
Human STIP1-31467TH Recombinant Human STIP1, His-tagged E.coli His
Human STIP1-5520H Recombinant Human Stress-Induced-Phosphoprotein 1 E.coli N/A
Human STIP1-1810H Recombinant Human Stress-induced-phosphoprotein 1, His-tagged E.coli His
Human STIP1-31468TH Recombinant Human STIP1 E.coli N/A
Human STIP1-641HCL Recombinant Human STIP1 lysate HEK293 N/A
Human STIP1-2967H Recombinant Human STIP1 Protein, His-tagged Insect Cell His
Human STIP1-2964H Recombinant Human STIP1 Protein, MYC/DDK-tagged HEK293 Myc/DDK
Human STIP1-1618HFL Recombinant Full Length Human STIP1 Protein, C-Flag-tagged Mammalian cells Flag
Human STIP1-020H Recombinant Human STIP1 Protein, His-tagged E.coli His 2-543
Human STIP1-670H Recombinant Human STIP1 Protein, His/GST-tagged E.coli His/GST Met1~Lys169
Human STIP1-1651H Recombinant Human STIP1 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human STIP1-2123H Recombinant Human STIP1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human STIP1-2123H-B Recombinant Human STIP1 Protein Pre-coupled Magnetic Beads HEK293
Human STIP1-101H Recombinant Human STIP1 Protein, His-tagged E. coli His 2-543
Human STIP1-5579H Recombinant Human STIP1 Protein (Met1-Lys169), N-His tagged E.coli N-His Met1-Lys169
Human STIP1-3536H Recombinant Human STIP1 protein, His-SUMO-tagged E.coli His-SUMO 1-543aa
Mouse STIP1-16130M Recombinant Mouse STIP1 Protein Mammalian Cell His
Mouse Stip1-127M Recombinant Mouse Stip1 protein, His-tagged E.coli His
Mouse STIP1-8800M Recombinant Mouse STIP1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse Stip1-6180M Recombinant Mouse Stip1 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Mouse STIP1-8800M-B Recombinant Mouse STIP1 Protein Pre-coupled Magnetic Beads HEK293
Rat STIP1-5789R Recombinant Rat STIP1 Protein Mammalian Cell His
Rat STIP1-5448R Recombinant Rat STIP1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat STIP1-5448R-B Recombinant Rat STIP1 Protein Pre-coupled Magnetic Beads HEK293
Zebrafish STIP1-1842Z Recombinant Zebrafish STIP1 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • STIP1 Related Research Area

STIP1 involved in several pathways and played different roles in them. We selected most pathways STIP1 participated on our site, such as Prion diseases, which may be useful for your reference. Also, other proteins which involved in the same pathway with STIP1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Prion diseasesBAX;PRKACA;C9;MAPK3;IL1A;MAP2K2;Hc;PRKACB;IL1B

STIP1 has several biochemical functions, for example, Hsp70 protein binding, chaperone binding, poly(A) RNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by STIP1 itself. We selected most functions STIP1 had, and list some proteins which have the same functions with STIP1. You can find most of the proteins on our site.

Function Related Protein
Hsp70 protein bindingL7RN6;DNAJC10;STIP1;FAM119A;METTL21A;DNAJB2;CDK1;MVD;GPR37
chaperone bindingTBCA;VWF;CDC37;DLST;HSPE1;BAG2;GRPEL2;BAK1;CTSC
poly(A) RNA bindingMRPS31;SLTM;HIST1H4H;FKBP3;NSA2;GFM1;HIST1H4J;FUBP1;MRPS28
protein C-terminus bindingATXN2;NEIL1;DLG4;HSPB7;NCL;SREBF2;TNNI3K;FBLN1;SNF8
protein bindingHNRNPF;ELP4;PRPSAP1;WDR48;SPDYE2;TIMM21;C19orf57;NUBP1;MAPKAPK3

STIP1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with STIP1 here. Most of them are supplied by our site. Hope this information will be useful for your research of STIP1.

HSP90AA1; NR3C1; VCAM1; EGFR; ACD; CDC37L1; CCDC117

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