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Recombinant Mouse Stip1 protein, His-tagged

Cat.No.: Stip1-127M
Product Overview: Recombinant Mouse Stip1(1-543aa) fused with His tag was expressed in E. coli.
Description: Stip1, also known as stress induced phosphoprotein 1, belongs to the large group of co-chaperones. The main function of Stip1 is to link Hsp70 and Hsp90 together. Stip1 also modulates the chaperone activities of the linked proteins and possibly interacts with other chaperones and proteins. It forms a complex with HSC70 and HSPCA/HSP-86 and HSPCB/HSP-84, as well as interacting with PACRG.
Source: E. coli
Species: Mouse
Tag : His
Form: Liquid. In 20mM Tris-HCl(pH8.0) containing 0.1M NaCl, 1mM DTT, 10% glycerol
Molecular Mass: 64.7 kDa (563aa) confirmed by MALDI-TOF
AA Sequence: MGSSHHHHHH SSGLVPRGSH MEQVNELKEK GNKALSAGNI DDALQCYSEA IKLDPQNHVL YSNRSAAYAK KGDYQKAYED GCKTVDLKPD
WGKGYSRKAA ALEFLNRFEE AKRTYEEGLK HEANNLQLKE GLQNMEARLA ERKFMNPFNL PNLYQKLEND PRTRSLLSDP TYRELIEQLQ
NKPSDLGTKL QDPRVMTTLS VLLGVDLGSM DEEEEAATPP PPPPPKKEPK PEPMEEDLPE NKKQALKEKE LGNDAYKKKD FDKALKHYDR
AKELDPTNMT YITNQAAVHF EKGDYNKCRE LCEKAIEVGR ENREDYRQIA KAYARIGNSY FKEEKYKDAI HFYNKSLAEH RTPDVLKKCQ
QAEKILKEQE RLAYINPDLA LEEKNKGNEC FQKGDYPQAM KHYTEAIKRN PRDAKLYSNR AACYTKLLEF QLALKDCEEC IQLEPTFIKG
YTRKAAALEA MKDYTKAMDV YQKALDLDSS CKEAADGYQR CMMAQYNRHD SPEDVKRRAM ADPEVQQIMS DPAMRLILEQ MQKDPQALSE
HLKNPVIAQK IQKLMDVGLI AIR
Purity: > 95% by SDS - PAGE
Applications: SDS-PAGE
Storage: Can be stored at +4 centigrade short term (1-2 weeks). For long term storage, aliquot and store at -20 centigrade or -70 centigrade. Avoid repeated freezing and thawing cycles.
Concentration: 1 mg/ml (determined by Absorbance at 280nm)
Gene Name: Stip1 stress-induced phosphoprotein 1 [ Mus musculus ]
Official Symbol: Stip1
Synonyms: STIP1; stress-induced phosphoprotein 1; stress-induced-phosphoprotein 1; mSTI1; IEF SSP 3521; stress-inducible protein; Hsp70/Hsp90 organizing protein; hsc70/Hsp90-organizing protein; Hop; p60; Sti1;
Gene ID: 20867
mRNA Refseq: NM_016737
Protein Refseq: NP_058017
UniProt ID: Q60864
Chromosome Location: 19; 19 A
Pathway: Prion diseases, organism-specific biosystem; Prion diseases, conserved biosystem;
Function: Hsp70 protein binding; binding; chaperone binding; protein C-terminus binding;

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Optional requirements on this protein    +Expand
C-fusion    N-fusion   Non-tagged
His    GST   Fc   Others
<1.0 eu/μg    <0.1 eu/μg   <0.01 eu/μg   Not required
Monomer Isolation    Dimer Isolation    Not required
>80% by SDS-PAGE    >90% by SDS-PAGE   >95% by SDS-PAGE   Others

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