SUMO1 Protein, small ubiquitin-like modifier 1

SUMO1

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SUMO1

Official Full Name small ubiquitin-like modifier 1
Background This gene encodes a protein that is a member of the SUMO (small ubiquitin-like modifier) protein family. It functions in a manner similar to ubiquitin in that it is bound to target proteins as part of a post-translational modification system. However, unlike ubiquitin which targets proteins for degradation, this protein is involved in a variety of cellular processes, such as nuclear transport, transcriptional regulation, apoptosis, and protein stability. It is not active until the last four amino acids of the carboxy-terminus have been cleaved off. Several pseudogenes have been reported for this gene. Alternate transcriptional splice variants encoding different isoforms have been characterized. [provided by RefSeq, Jul 2008]
Synonyms SUMO1; small ubiquitin-like modifier 1; DAP1; GMP1; PIC1; SMT3; UBL1; OFC10; SENP2; SMT3C; SMT3H3; small ubiquitin-related modifier 1; sentrin; SMT3 homolog 3; GAP modifying protein 1; ubiquitin-like protein UBL1; ubiquitin-like protein SMT3C; SMT3 suppressor of mif two 3 homolog 1; ubiquitin-homology domain protein PIC1;
    • Species :
    • Chicken
    • Human
    • Mouse
    • Rat
    • Rhesus Macaque
    • Zebrafish
    • Source :
    • E.coli
    • HEK293
    • Human
    • Mammalian Cell
    • Tag :
    • GST
    • HA
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human SUM01-12H Recombinant Human SUMO1 E.coli N/A
    Human SUMO1-1293H Recombinant Human SMT3 Suppressor Of Mif Two 3 Homolog 1 (S. Cerevisiae), His-tagged Human His
    Human SUMO1-1344HCL Recombinant Human SUMO1 293 Cell Lysate HEK293 N/A
    Human SUMO1-20H Recombinant Human Small Ubiquitin-related Modifier 1 E.coli N/A
    Human SUMO1-249H Recombinant Human SUMO1, His-tagged E.coli His
    Human SUMO1-3054H Recombinant Human SUMO1, GST-tagged E.coli GST
    Human SUMO1-558H Recombinant Human SUMO1 E.coli N/A
    Human SUMO1-559H Recombinant Human SUMO1, HA (YPYDVPDYA)-tagged E.coli HA
    Human SUMO1-560H Recombinant Human SUMO1 E.coli N/A
    Human SUMO1-561H Recombinant Human SUMO1, His-tagged E.coli His
    Human SUMO1-562H Recombinant Human SUMO1 E.coli N/A
    Human SUMO1-563H Recombinant Human SUMO1 E.coli N/A
    Human SUMO1-564H Recombinant Human SUMO1 E.coli N/A
    Human SUMO1-565H Recombinant Human SUMO1 E.coli N/A
    Human SUMO1-566H Recombinant Human SUMO1 E.coli N/A
    Human SUMO1-567H Recombinant Human SUMO1 E.coli N/A
    Human SUMO1-568H Recombinant Human SUMO1 E.coli N/A
    Human SUMO1-569H Recombinant Human SUMO1 E.coli N/A
    Human SUMO1-7040H Recombinant Human SUMO1 protein, His-tagged E.coli His
    Mouse SUMO1-16237M Recombinant Mouse SUMO1 Protein Mammalian Cell His
    Rat SUMO1-5839R Recombinant Rat SUMO1 Protein Mammalian Cell His
    Rhesus Macaque SUMO1-4560R Recombinant Rhesus monkey SUMO1 Protein, His-tagged Mammalian Cell His
    Chicken SUMO1-5711C Recombinant Chicken SUMO1 Mammalian Cell His
    Zebrafish SUMO1-12375Z Recombinant Zebrafish SUMO1 Mammalian Cell His

    SUMO1 involved in several pathways and played different roles in them. We selected most pathways SUMO1 participated on our site, such as RNA transport, which may be useful for your reference. Also, other proteins which involved in the same pathway with SUMO1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    RNA transport EIF3HB; RPP21; PEAK1; ELAC2; TPR; EEF1A1L1; EIF2B5; NUP160; EIF4A1A; EIF3I

    SUMO1 has several biochemical functions, for example, SUMO transferase activity, ion channel binding, poly(A) RNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SUMO1 itself. We selected most functions SUMO1 had, and list some proteins which have the same functions with SUMO1. You can find most of the proteins on our site.

    Function Related Protein
    SUMO transferase activity UBE2I; SUMO1; NSMCE2; SUMO3; PIAS4; UBE2IA; UBE2IB; SUMO4; PIAS3; CBX4
    ion channel binding KCND3; ACTN4; ACTN2; KCNIP2; USP10; NOS1; TCAP; KCNH5; RNF207; PRKCSH
    poly(A) RNA binding QKI; MACF1; MECP2; MAGOH; ERAL1; TOP2A; SNRNP70; BAG4; BZW1; EIF3L
    potassium channel regulator activity SGK3; KCNS3; KCNE2; KCNIP3; SGK1; DPP10; SUMO1; KCNAB2; CHP; KCNMB4
    protein binding DESI1; C22orf13; HSPA1L; F2RL1; KRT25; AREG; IFITM3; KIF20B; CASP9; NTN4
    protein tag SUMO1; SUMO2; SUMO3B; RNF41; NFATC2IP; SUMO3A; UBL5; SUMO3; SUMO4; ISG15
    transcription factor binding MAFB; TRIM11; MYOD1; TFDP2; TRAPPC2; BRD7; TRIM6; DRG1; PIM1; CREBBP
    ubiquitin protein ligase binding PML; ABI2; PRKACB; HSPA9; UBXN1; UBE2G1B; GGN; JAK1; GABARAPL2; TRAF4

    SUMO1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SUMO1 here. Most of them are supplied by our site. Hope this information will be useful for your research of SUMO1.

    UBE2I; DAXX; SP100

    Collaud, S; Tischler, V; et al. Lung neuroendocrine tumors: correlation of ubiquitinylation and sumoylation with nucleo-cytosolic partitioning of PTEN. BMC CANCER 15:-(2015).
    Barysch, SV; Dittner, C; et al. Identification and analysis of endogenous SUMO1 and SUMO2/3 targets in mammalian cells and tissues using monoclonal antibodies. NATURE PROTOCOLS 9:896-909(2014).

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