|Official Full Name||small ubiquitin-like modifier 1|
|Background||This gene encodes a protein that is a member of the SUMO (small ubiquitin-like modifier) protein family. It functions in a manner similar to ubiquitin in that it is bound to target proteins as part of a post-translational modification system. However, unlike ubiquitin which targets proteins for degradation, this protein is involved in a variety of cellular processes, such as nuclear transport, transcriptional regulation, apoptosis, and protein stability. It is not active until the last four amino acids of the carboxy-terminus have been cleaved off. Several pseudogenes have been reported for this gene. Alternate transcriptional splice variants encoding different isoforms have been characterized. [provided by RefSeq, Jul 2008]|
|Synonyms||SUMO1; small ubiquitin-like modifier 1; DAP1; GMP1; PIC1; SMT3; UBL1; OFC10; SENP2; SMT3C; SMT3H3; small ubiquitin-related modifier 1; sentrin; SMT3 homolog 3; GAP modifying protein 1; ubiquitin-like protein UBL1; ubiquitin-like protein SMT3C; SMT3 suppressor of mif two 3 homolog 1; ubiquitin-homology domain protein PIC1;|
|Species||Cat.#||Product name||Source (Host)||Tag||Protein Length||Price|
SUMO1 involved in several pathways and played different roles in them. We selected most pathways SUMO1 participated on our site, such as RNA transport, which may be useful for your reference. Also, other proteins which involved in the same pathway with SUMO1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
|Pathway Name||Pathway Related Protein|
|RNA transport||EIF3HB; RPP21; PEAK1; ELAC2; TPR; EEF1A1L1; EIF2B5; NUP160; EIF4A1A; EIF3I|
SUMO1 has several biochemical functions, for example, SUMO transferase activity, ion channel binding, poly(A) RNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SUMO1 itself. We selected most functions SUMO1 had, and list some proteins which have the same functions with SUMO1. You can find most of the proteins on our site.
|SUMO transferase activity||UBE2I; SUMO1; NSMCE2; SUMO3; PIAS4; UBE2IA; UBE2IB; SUMO4; PIAS3; CBX4|
|ion channel binding||KCND3; ACTN4; ACTN2; KCNIP2; USP10; NOS1; TCAP; KCNH5; RNF207; PRKCSH|
|poly(A) RNA binding||QKI; MACF1; MECP2; MAGOH; ERAL1; TOP2A; SNRNP70; BAG4; BZW1; EIF3L|
|potassium channel regulator activity||SGK3; KCNS3; KCNE2; KCNIP3; SGK1; DPP10; SUMO1; KCNAB2; CHP; KCNMB4|
|protein binding||DESI1; C22orf13; HSPA1L; F2RL1; KRT25; AREG; IFITM3; KIF20B; CASP9; NTN4|
|protein tag||SUMO1; SUMO2; SUMO3B; RNF41; NFATC2IP; SUMO3A; UBL5; SUMO3; SUMO4; ISG15|
|transcription factor binding||MAFB; TRIM11; MYOD1; TFDP2; TRAPPC2; BRD7; TRIM6; DRG1; PIM1; CREBBP|
|ubiquitin protein ligase binding||PML; ABI2; PRKACB; HSPA9; UBXN1; UBE2G1B; GGN; JAK1; GABARAPL2; TRAF4|
SUMO1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SUMO1 here. Most of them are supplied by our site. Hope this information will be useful for your research of SUMO1.
UBE2I; DAXX; SP100