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SUMO4

  • Official Full Name

    SMT3 suppressor of mif two 3 homolog 4

  • Overview

    This gene is a member of the SUMO gene family. This family of genes encode small ubiquitin-related modifiers that are attached to proteins and control the target proteins subcellular localization, stability, or activity. The protein described in this record is located in the cytoplasm and specifically modifies IKBA, leading to negative regulation of NF-kappa-B-dependent transcription of the IL12B gene. A specific polymorphism in this SUMO gene, which leads to the M55V substitution, has been associated with type I diabetes. The RefSeq contains this polymorphism.
  • Synonyms

    SUMO4; SMT3 suppressor of mif two 3 homolog 4 (S. cerevisiae); SMT3 suppressor of mif two 3 homolog 4 (yeast) , SMT3H4; small ubiquitin-related modifier 4; dJ281H8.4; SMT3 suppressor of mif two 3 homolog 2; small ubiquitin-like modifier 4 protein; IDDM5;
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human SUMO4-1723HCL Recombinant Human SUMO4 cell lysate N/A
Human SUMO4-4514H Recombinant Human SUMO4 protein, GST-tagged E.coli GST 1-95aa
Human SUMO4-3015H Recombinant Human SUMO4 Protein, His-tagged E.coli His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • SUMO4 Related Research Area
  • SUMO4 Related Signal Pathway

SUMO4 involved in several pathways and played different roles in them. We selected most pathways SUMO4 participated on our site, such as RNA transport, which may be useful for your reference. Also, other proteins which involved in the same pathway with SUMO4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
RNA transportGEMIN7;TACC3;UPF3B;EIF4E1C;EIF4BA;PNN;SUMO3;TPR;GEMIN2

SUMO4 has several biochemical functions, for example, SUMO transferase activity, protein tag. Some of the functions are cooperated with other proteins, some of the functions could acted by SUMO4 itself. We selected most functions SUMO4 had, and list some proteins which have the same functions with SUMO4. You can find most of the proteins on our site.

Function Related Protein
SUMO transferase activityUBE2IA;MUL1;PIAS3;SUMO3;UBE2IB;PIAS4;TOPORS;UBE2I;CBX4
protein tagSUMO2B;UBL5;SUMO3B;SUMO3;ISG15;RNF41;SUMO1;SUMO2;SUMO3A

SUMO4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SUMO4 here. Most of them are supplied by our site. Hope this information will be useful for your research of SUMO4.

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