|Official Full Name||SMT3 suppressor of mif two 3 homolog 4|
|Background||This gene is a member of the SUMO gene family. This family of genes encode small ubiquitin-related modifiers that are attached to proteins and control the target proteins subcellular localization, stability, or activity. The protein described in this record is located in the cytoplasm and specifically modifies IKBA, leading to negative regulation of NF-kappa-B-dependent transcription of the IL12B gene. A specific polymorphism in this SUMO gene, which leads to the M55V substitution, has been associated with type I diabetes. The RefSeq contains this polymorphism.|
|Synonyms||SUMO4; SMT3 suppressor of mif two 3 homolog 4 (S. cerevisiae); SMT3 suppressor of mif two 3 homolog 4 (yeast) , SMT3H4; small ubiquitin-related modifier 4; dJ281H8.4; SMT3 suppressor of mif two 3 homolog 2; small ubiquitin-like modifier 4 protein; IDDM5|
|Species||Cat.#||Product name||Source (Host)||Tag||Protein Length||Price|
SUMO4 involved in several pathways and played different roles in them. We selected most pathways SUMO4 participated on our site, such as RNA transport, which may be useful for your reference. Also, other proteins which involved in the same pathway with SUMO4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
|Pathway Name||Pathway Related Protein|
|RNA transport||NDC1; PRMT5; EIF3A; AAAS; EIF2B1; SEH1L; EIF3J; EEF1A1L2; PABPC1L2A; THOC1|
SUMO4 has several biochemical functions, for example, SUMO transferase activity, protein tag. Some of the functions are cooperated with other proteins, some of the functions could acted by SUMO4 itself. We selected most functions SUMO4 had, and list some proteins which have the same functions with SUMO4. You can find most of the proteins on our site.
|SUMO transferase activity||SUMO3; SUMO1; UBE2IA; MUL1; CBX4; PIAS4; UBE2IB; TOPORS; PIAS3; UBE2I|
|protein tag||ISG15; SUMO2; NFATC2IP; SUMO1; SUMO3A; SUMO3B; UBL5; RNF41; SUMO2B; SUMO4|
SUMO4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SUMO4 here. Most of them are supplied by our site. Hope this information will be useful for your research of SUMO4.