TAS1R3 Protein, taste receptor, type 1, member 3


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Official Full Name taste receptor, type 1, member 3
Background The TAS1R3 gene encodes the human homolog of mouse Sac, a major determinant of differences between sweet-sensitive and -insensitive mouse strains in their responsiveness to sucrose, saccharine, and other sweeteners (Max et al., 2001
Synonyms TAS1R3; taste receptor, type 1, member 3; taste receptor type 1 member 3; T1R3; G protein coupled receptor; Sac; Saccharin preference; Sweet taste receptor T1R3; T1 R3; T1R 3; TAS1 R3; TAS1R 3; Taste receptor type 1 member 3 precursor; TR 3; TR3; TS1R3_HUMAN
    • Species :
    • Human
    • Rat
    • Zebrafish
    • Source :
    • HEK293
    • HEK293T
    • Mammalian Cell
    • Tag :
    • His
    • Myc
    • DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human TAS1R3-1247HCL Recombinant Human TAS1R3 293 Cell Lysate HEK293 N/A
    Human TAS1R3-18HCL Recombinant Human TAS1R3 HEK293T cell lysate HEK293T Myc/DDK
    Human TAS1R3-770H Recombinant Human TAS1R3 Mammalian Cell His
    Rat TAS1R3-5933R Recombinant Rat TAS1R3 Protein Mammalian Cell His
    Zebrafish TAS1R3-3632Z Recombinant Zebrafish TAS1R3 Mammalian Cell His

    TAS1R3 involved in several pathways and played different roles in them. We selected most pathways TAS1R3 participated on our site, such as Taste transduction, Carbohydrate digestion and absorption, which may be useful for your reference. Also, other proteins which involved in the same pathway with TAS1R3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Taste transduction TAS2R3; TAS2R138; SCNN1G; TAS2R110; PRKACA; PRKACB; KCNB1; TAS2R136; TAS2R20; TAS2R137
    Carbohydrate digestion and absorption ATP1B2; AKT2; G6PC2; PRKCB; PLCB2; ATP1A4; AKT1; SLC2A5; FXYD2; PIK3R3

    TAS1R3 has several biochemical functions, for example, protein heterodimerization activity, contributes_to sweet taste receptor activity, taste receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by TAS1R3 itself. We selected most functions TAS1R3 had, and list some proteins which have the same functions with TAS1R3. You can find most of the proteins on our site.

    Function Related Protein
    protein heterodimerization activity Bcl2a1b; AGTR1; TLR1; RALGAPA1; SFRP5; YWHAH; BTBD11; CENPA; IKBKG; MYOD1
    contributes_to sweet taste receptor activity TAS1R2; TAS1R3
    taste receptor activity TAS2R136; TAS2R140; TAS2R139; TAS2R3; TAS2R143; TAS2R108; TAS2R7; TAS2R137; GPR120; TAS2R134
    contributes_to taste receptor activity TAS1R2; TAS1R3

    TAS1R3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TAS1R3 here. Most of them are supplied by our site. Hope this information will be useful for your research of TAS1R3.

    Yasumatsu, K; Manabe, T; et al. Involvement of multiple taste receptors in umami taste: analysis of gustatory nerve responses in metabotropic glutamate receptor 4 knockout mice. JOURNAL OF PHYSIOLOGY-LONDON 593:1021-1034(2015).
    Maruoka, D; Arai, M; et al. Mosapride Citrate Increases Postprandial Glucagon-Like Peptide-1, Insulin, and Gene Expression of Sweet Taste Receptors. DIGESTIVE DISEASES AND SCIENCES 60:345-353(2015).

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