TCP1
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Official Full Name
t-complex 1
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Overview
T-complex protein 1 subunit alpha is a protein that in humans is encoded by the TCP1 gene. -
Synonyms
TCP1; t-complex 1; T-complex protein 1 subunit alpha; CCT1; Ccta; D6S230E; tailless complex polypeptide 1; T-complex protein 1, alpha subunit; CCT-alpha; TCP-1-alpha;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Chicken
- Cynomolgus Monkey
- Human
- Mouse
- Rat
- Rhesus Macaque
- Zebrafish
- E.coli
- HEK293
- HEK293T
- Mammalian Cell
- Mammalian cells
- C
- His
- Flag
- His (Fc)
- Avi
- Myc
- DDK
- N/A
- N
- GST
- Involved Pathway
- Protein Function
- Interacting Protein
- TCP1 Related Articles
TCP1 involved in several pathways and played different roles in them. We selected most pathways TCP1 participated on our site, such as Assembly of the primary cilium, Association of TriC/CCT with target proteins during biosynthesis, BBSome-mediated cargo-targeting to cilium, which may be useful for your reference. Also, other proteins which involved in the same pathway with TCP1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Assembly of the primary cilium | ARL13B;DYNLL2;BBS1;CSNK1D;DCTN3;TCTN1;CNGA2;CEP57;IQCB1 |
| Association of TriC/CCT with target proteins during biosynthesis | FBXL5;CCT3;CCT7;FBXW4;FBXW2;FBXW9;KIFC3;CCT6A;CCT5 |
| BBSome-mediated cargo-targeting to cilium | BBS12;BBS4;BBS2;CCT8;CCT5;CCT4;CCT3;CCT2;TCP1 |
| Cargo trafficking to the periciliary membrane | EXOC3;BBS12;NPHP3;ARF4;BBS2;ARF4A;CCT2;UNC119.1;MKKS |
| Chaperonin-mediated protein folding | PFDN5;FKBP9;PFDN6;CCT6A;TUBA1B;FBXL5;CCT5;VBP1;FBXW2 |
| Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding | TUBB4A;CCT4;CCT6A;CCT3;CCT2;PFDN1;TUBA3D;PFDN2;PFDN6 |
| Folding of actin by CCT/TriC | CCT4;CCT8;CCT7;CCT5;CCT6A;TCP1;CCT2;CCT3 |
| Formation of tubulin folding intermediates by CCT/TriC | CCT7;TCP1;CCT6A;CCT5;CCT3;TUBB4A;TUBB4B;CCT8;CCT2 |
TCP1 has several biochemical functions, for example, ATP binding, poly(A) RNA binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by TCP1 itself. We selected most functions TCP1 had, and list some proteins which have the same functions with TCP1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| ATP binding | DDX50;FER;UCK2;CAD;TTLL5;GATB;ABCD3B;MAPK4;DARS2 |
| poly(A) RNA binding | NKRF;EWSR1;DUSP14;UTP15;SF3B14;GNL3L;MRPL9;TRIM25;CHST13 |
| protein binding | RFX5;PRKAA2;ASPH;RIBC2;EPRS;CSNK1D;FAM126B;PCGF3;CSTF2 |
| ubiquitin protein ligase binding | ZFP746;UBE2K;UBE2V2;LTBR;HIF1A;UBE2KA;BRCA1;PRKAR2A;C10orf46 |
| unfolded protein binding | NDUFAF1;HSP26;DNAJB5;DNAJA1;DNAJB1B;PDRG1;TUBB4B;PFDN5;ERLEC1 |
TCP1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TCP1 here. Most of them are supplied by our site. Hope this information will be useful for your research of TCP1.
PPP2CA; PPP4C; PPP2CB; OLR1; STRN3; ILK
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