• Official Full Name
  • transmembrane 4 L six family member 1
  • Background
  • The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface antigen and is highly expressed in different carcinomas. [provided by RefSeq, Jul 2008]
  • Synonyms
  • TM4SF1; transmembrane 4 L six family member 1; L6; H-L6; M3S1; TAAL6; transmembrane 4 L6 family member 1; tumor-associated antigen L6; transmembrane 4 superfamily member 1; membrane component chromosome 3 surface marker 1; membrane component, chromosome 3, surface marker 1;
Source (Host):YeastSpecies:Human
Product nameRecombinant Human TM4SF1 Protein (115-161 aa), His-tagged
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human TM4SF1, GST-tagged
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse TM4SF1 Protein
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey TM4SF1 Protein, His-tagged
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken TM4SF1
Source (Host):HEK293Species:Human
Product nameRecombinant Human TM4SF1 lysate

Protein Function

TM4SF1 has several biochemical functions, for example, molecular_function. Some of the functions are cooperated with other proteins, some of the functions could acted by TM4SF1 itself. We selected most functions TM4SF1 had, and list some proteins which have the same functions with TM4SF1. You can find most of the proteins on our site.
Related Protein
Function molecular_function
Related Protein PLEKHM3; HEATR8; GM216; DRAM2B; CLTA; SYNGR3A; SDAD1; CRYGM2D16; TAS2R117; PMP22B

Interacting Protein

TM4SF1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TM4SF1 here. Most of them are supplied by our site. Hope this information will be useful for your research of TM4SF1.

TM4SF1 Related Articles

Choi, SI; Kim, SY; et al. TM4SF4 overexpression in radiation-resistant lung carcinoma cells activates IGF1R via elevation of IGF1. ONCOTARGET 5:9823-9837(2014).
Lin, CI; Merley, A; et al. TM4SF1: a new vascular therapeutic target in cancer. ANGIOGENESIS 17:897-907(2014).