tnfaip6
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  • Official Full Name
  • tumor necrosis factor, alpha-induced protein 6
  • Background
  • The protein encoded by this gene is a secretory protein that contains a hyaluronan-binding domain, and thus is a member of the hyaluronan-binding protein family. The hyaluronan-binding domain is known to be involved in extracellular matrix stability and cell migration. This protein has been shown to form a stable complex with inter-alpha-inhibitor (I alpha I), and thus enhance the serine protease inhibitory activity of I alpha I, which is important in the protease network associated with inflammation. This gene can be induced by proinflammatory cytokines such as tumor necrosis factor alpha and interleukin-1. Enhanced levels of this protein are found in the synovial fluid of patients with osteoarthritis and rheumatoid arthritis.
  • Synonyms
  • TNFAIP6; tumor necrosis factor, alpha-induced protein 6; tumor necrosis factor-inducible gene 6 protein; TSG 6; TSG6; Hyaluronate binding protein; TNF stimulated gene 6 protein; TNFAIP 6; Tumor necrosis factoralpha induced protein 6; Tumor necrosis factor alpha induced protein 6; Tumor necrosis factor stimulated gene 6 protein; OTTHUMP00000162710; TNF alpha-induced protein 6; hyaluronate-binding protein; TNF-stimulated gene 6 protein; tumor necrosis factor alpha-inducible protein 6; tumor necrosis factor-stimulated gene-6 protein; TSG-6
Cat.#:TNFAIP6-25MTag:His
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse TNFAIP6 Protein, His-tagged
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Cat.#:TNFAIP6-3005HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human TNFAIP6 protein, GST-tagged
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Cat.#:TNFAIP6-3315HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human TNFAIP6, His-tagged
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Cat.#:TNFAIP6-42HTag:His
Source (Host):NS0Species:Human
Product nameRecombinant Human TNFAIP6 protein, His-tagged
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Cat.#:Tnfaip6-1417MTag:His|T7
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Tnfaip6 protein, His & T7-tagged
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Cat.#:TNFAIP6-17146MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse TNFAIP6 Protein
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Cat.#:Tnfaip6-916MTag:His
Source (Host):NSO CellsSpecies:Mouse
Product nameRecombinant Mouse Tnfaip6 Protein, His-tagged
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Cat.#:TNFAIP6-4863RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey TNFAIP6 Protein, His-tagged
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Cat.#:TNFAIP6-3306CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken TNFAIP6
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Cat.#:TNFAIP6-3730ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish TNFAIP6
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Cat.#:TNFAIP6-3004HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Tumor Necrosis Factor, Alpha-Induced Protein 6, His-tagged
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Cat.#:TNFAIP6-896HCLTag:N/A
Source (Host):Species:Human
Product nameRecombinant Human TNFAIP6 293 Cell Lysate
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Protein Function

TNFAIP6 has several biochemical functions, for example, hyaluronic acid binding. Some of the functions are cooperated with other proteins, some of the functions could acted by TNFAIP6 itself. We selected most functions TNFAIP6 had, and list some proteins which have the same functions with TNFAIP6. You can find most of the proteins on our site.
Function
Related Protein
Function hyaluronic acid binding
Related Protein HAPLN1A; STAB2; VCANB; NCAN; HAPLN3; BCAN; HAPLN4; ACAN; C1QBP; LYVE1

TNFAIP6 Related Articles

Jang, YJ; Park, JI; et al. Cumulus Cell-Expressed Type I Interferons Induce Cumulus Expansion in Mice. BIOLOGY OF REPRODUCTION 92:-(2015).
Anderson, RA; Bayne, RAL; et al. Brain-derived neurotrophic factor is a regulator of human oocyte maturation and early embryo development. FERTILITY AND STERILITY 93:1394-1406(2010).
Nagyova, E; Camaioni, A; et al. Synthesis of tumor necrosis factor alpha-induced protein 6 in porcine preovulatory follicles: A study with A38 antibody. BIOLOGY OF REPRODUCTION 78:903-909(2008).