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TPD52L1

  • Official Full Name

    tumor protein D52-like 1

  • Overview

    This gene encodes a member of the tumor protein D52 (TPD52) family. The encoded protein contains a coiled-coil domain and may form homo- or hetero-dimer with TPD52 family members. The protein is reported to be involved in cell proliferation and calcium signaling. It also interacts with the mitogen-activated protein kinase kinase kinase 5 (MAP3K5/ASK1) and positively regulates MAP3K5-induced apoptosis. Multiple alternatively spliced transcript variants have been observed, but the full-length nature of some variants has not yet been determined.
  • Synonyms

    TPD52L1; tumor protein D52-like 1; tumor protein D53; D53; hD53; MGC8556;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Human
  • Mouse
  • Rhesus Macaque
  • Zebrafish
  • E.coli
  • HEK293
  • HEK293T
  • Mammalian Cell
  • GST
  • His
  • His (Fc)
  • Avi
  • Myc
  • DDK
  • Myc|DDK
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human TPD52L1-222H Recombinant Human TPD52L1, His-tagged E.coli His
Human TPD52L1-13702H Recombinant Human TPD52L1, GST-tagged E.coli GST 1-144a.a.
Human TPD52L1-31598TH Recombinant Human TPD52L1, His-tagged E.coli His
Human TPD52L1-1813HCL Recombinant Human TPD52L1 cell lysate N/A
Human TPD52L1-2279H Recombinant Human TPD52L1 Protein, MYC/DDK-tagged HEK293 Myc/DDK
Human TPD52L1-2086H Recombinant Human TPD52L1 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Mouse TPD52L1-17250M Recombinant Mouse TPD52L1 Protein Mammalian Cell His
Mouse Tpd52l1-6592M Recombinant Mouse Tpd52l1 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Mouse TPD52L1-9531M Recombinant Mouse TPD52L1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse TPD52L1-9531M-B Recombinant Mouse TPD52L1 Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque TPD52L1-4917R Recombinant Rhesus monkey TPD52L1 Protein, His-tagged Mammalian Cell His
Rhesus Macaque TPD52L1-4731R Recombinant Rhesus Macaque TPD52L1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque TPD52L1-4731R-B Recombinant Rhesus Macaque TPD52L1 Protein Pre-coupled Magnetic Beads HEK293
Zebrafish TPD52L1-2878Z Recombinant Zebrafish TPD52L1 Mammalian Cell His
Chicken TPD52L1-5789C Recombinant Chicken TPD52L1 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • TPD52L1 Related Articles

TPD52L1 involved in several pathways and played different roles in them. We selected most pathways TPD52L1 participated on our site, such as Clathrin derived vesicle budding, Golgi Associated Vesicle Biogenesis, Membrane Trafficking, which may be useful for your reference. Also, other proteins which involved in the same pathway with TPD52L1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Clathrin derived vesicle buddingAP4B1;AP1M2;CNO;PICALMA;PICALMB;DTNBP1B;TGOLN2;AP1G1;SNX9
Golgi Associated Vesicle BiogenesisTBC1D8B;TFR1B;TPD52L1;NAPAA;DTNBP1;SNX9B;TCEAL4;YIPF6;CLINT1
Membrane TraffickingCOPG;SEC23IP;NSFA;FTH1A;CLVS1;PICALM;YKT6;BLOC1S1;GJD3
Vesicle-mediated transportTRAPPC2L;NAPB;TRAPPC3;CX27.5;TRAPPC2;SNF8;SNX9A;TERFA;COPE
trans-Golgi Network Vesicle BuddingTBC1D8B;AP3S1;BLOC1S3;SNX9;CLVS2;TPD52;HIP1R;SNAPIN;PICALMA

TPD52L1 has several biochemical functions, for example, identical protein binding, protein binding, protein heterodimerization activity. Some of the functions are cooperated with other proteins, some of the functions could acted by TPD52L1 itself. We selected most functions TPD52L1 had, and list some proteins which have the same functions with TPD52L1. You can find most of the proteins on our site.

Function Related Protein
identical protein bindingBCHE;CLDN16;TTR;GOT2;BCL2;AGXT2;MAP3K11;CEACAM16;PYCARD
protein bindingTRIM74;CTTNBP2NL;RXRG;TAGLN;Reln;PPP6C;HEPACAM2;Cd79a, Cd79b;PCOLCE
protein heterodimerization activityTAS1R2;IKBKG;HIST1H2BN;TXLNG;CAV1;PRPH;SMC4;BCL11A;BOK
protein homodimerization activityTAP1;TCF3;UNC13A;CD2;PEX11A;CHRNA7;QPRT;RNF17;ZBTB16

TPD52L1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TPD52L1 here. Most of them are supplied by our site. Hope this information will be useful for your research of TPD52L1.

YWHAB; YWHAZ; TPD52L2; TPD52L2; EIF3J; SFN; ABL2; TPD52; HDAC1

Yamaga, R; Ikeda, K; et al. RNA Sequencing of MCF-7 Breast Cancer Cells Identifies Novel Estrogen-Responsive Genes with Functional Estrogen Receptor-Binding Sites in the Vicinity of Their Transcription Start Sites. HORMONES & CANCER 4:222-232(2013).
Fanayan, S; Shehata, M; et al. Mucin 1 (MUC1) is a novel partner for MAL2 in breast carcinoma cells. BMC CELL BIOLOGY 10:-(2009).
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