Recombinant Human TPD52L1, His-tagged

• Cat.No.: TPD52L1-31598TH
• Product Overview: Recombinant fusion protein, corresponding to amino acids 1-128 of Human TPD52L1, with N-terminal His-tag.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Protein Length: 1-128 a.a.
• Description: This gene encodes a member of the tumor protein D52 (TPD52) family. The encoded protein contains a coiled-coil domain and may form homo- or hetero-dimer with TPD52 family members. The protein is reported to be involved in cell proliferation and calcium signaling. It also interacts with the mitogen-activated protein kinase kinase kinase 5 (MAP3K5/ASK1) and positively regulates MAP3K5-induced apoptosis. Multiple alternatively spliced transcript variants have been observed, but the full-length nature of some variants has not yet been determined.
• Conjugation: HIS
• Form: Liquid
• Purity: >90% by SDS-PAGE
• Storage buffer: Preservative: NoneConstituents: PBS, pH 7.4
• Storage: Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
• Sequences of amino acids: MGSSHHHHHH SSGLVPRGSH MEAQAQGLLE TEPLQGTDED AVASADFSSMLSEEEKEELK AELVQLEDEI TTLRQVLSAK ERHLVEIKQK LGMNLMNELKQNFSKSWHDM QTTTAYKKTH ETLSHAGQKA TAAFSNVGTA ISKKFGDMRR K
• Sequence Similarities: Belongs to the TPD52 family.

Gene Information

• Gene Name: TPD52L1 tumor protein D52-like 1 [ Homo sapiens ]
• Official Symbol: TPD52L1
• Synonyms: TPD52L1; tumor protein D52-like 1; tumor protein D53; D53; hD53
• Gene ID: 7164
• mRNA Refseq: NM_001003395
• Protein Refseq: NP_001003395
• MIM: 604069
• Uniprot ID: Q16890
• Chromosome Location: 6q22-q23
• Pathway: Clathrin derived vesicle budding, organism-specific biosystem; Golgi Associated Vesicle Biogenesis, organism-specific biosystem; Membrane Trafficking, organism-specific biosystem; trans-Golgi Network Vesicle Budding, organism-specific biosystem
• Function: cysteine-type endopeptidase activator activity involved in apoptotic process; identical protein binding; protein binding; protein heterodimerization activity; protein homodimerization activity