treml2
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  • Official Full Name
  • triggering receptor expressed on myeloid cells-like 2
  • Background
  • TREML2 is located in a gene cluster on chromosome 6 with the single Ig variable (IgV) domain activating receptors TREM1;(MIM 605085) and TREM2 (MIM 605086), but it has distinct structural and functional properties (Allcock et al., 2003;(PubMed 12645956)).
  • Synonyms
  • TREML2; triggering receptor expressed on myeloid cells-like 2; trem-like transcript 2 protein; TLT-2; triggering receptor expressed on myeloid cells-like protein 2; triggering receptor expressed on myeloid cells-like 2a dominant; Tlt2; Gm750; AW049306
Cat.#:TREML2-3227HTag:His
Source (Host):HEK293Species:Human
Product nameRecombinant Human TREML2, His tagged
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Cat.#:TREML2-427HTag:Fc
Source (Host):HEK293 cellsSpecies:Human
Product nameRecombinant Human TREML2 Protein, Fc-tagged
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Cat.#:TREML2-521HTag:Fc Chimera
Source (Host):NSO cellsSpecies:Human
Product nameRecombinant Human TREML2, Fc Chimera
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Cat.#:TREML2-17323MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse TREML2 Protein
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Cat.#:TREML2-3625CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken TREML2
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Cat.#:TREML2-3627CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken TREML2
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Cat.#:TREML2-2237HCLTag:N/A
Source (Host):HEK293Species:Human
Product nameRecombinant Human TREML2 cell lysate
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Involved Pathway

TREML2 involved in several pathways and played different roles in them. We selected most pathways TREML2 participated on our site, such as Adaptive Immune System, Immune System, Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell, which may be useful for your reference. Also, other proteins which involved in the same pathway with TREML2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Adaptive Immune System
HCST; FGF8B; EGFR; GM11711; KIF26A; RAET1E; CD96; ITK; CLTA; AGO3
Immune System
ARIH1L; CISH; CD300LB; OSCAR; DEFB104A; KIF5B; EDARADD; CTSD; TNIP2; RNF138
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
AF251705; SIGLEC6; CD300LF; NCR3LG1; CD200R2; CLEC2H; KLRF1; TREML2; CD300LB; Siglece

Protein Function

TREML2 has several biochemical functions, for example, protein binding, receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by TREML2 itself. We selected most functions TREML2 had, and list some proteins which have the same functions with TREML2. You can find most of the proteins on our site.
Function
Related Protein
Function protein binding
Related Protein MED6; SLC9A7; RGS1; DPYSL4; HAX1; PDE6D; PIH1D2; UNC45A; CSDC2; RPL12
Function receptor activity
Related Protein CD4; TREM2; GFRA1B; CALCR; GRIN1B; STRA6; NOTCH4; CD200R3; TREM1; TLR3

Interacting Protein

TREML2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TREML2 here. Most of them are supplied by our site. Hope this information will be useful for your research of TREML2.
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