Recombinant Human TREML2 Protein, Fc-tagged

• Cat.No.: TREML2-427H
• Product Overview: Recombinant Human TREML2 fused with Fc tag at C-terminal was expressed in HEK293 cells.

Specification

• Description: TREML2 is located in a gene cluster on chromosome 6 with the single Ig variable (IgV) domain activating receptors TREM1 (MIM 605085) and TREM2 (MIM 605086), but it has distinct structural and functional properties (Allcock et al., 2003 [PubMed 12645956]).
• Source: HEK293 cells
• Species: Human
• Tag: Fc
• Form: Lyophilized from a 0.2 µM filtered solution of PBS, pH 7.4
• Molecular Mass: 54.2kD
• AA Sequence: GPSADSVYTKVRLLEGETLSVQCSY KGYKNRVEGKVWCKIRKKKCEPGFA RVWVKGPRYLLQDDAQAKVVNITMV ALKLQDSGRYWCMRNTSGILYPLMG FQLDVSPAPQSERNIPFTHLDNILK SGTVTTGQAPTSGPDAPFTTGVMVF TPGLITLPRLLASTRPASKTGYSFT ATSTTSQGPRRTMGSQTVTASPSNA RDSSAGPESISTKSGDLSTRSPTTG LCLTSRSLLNRLPSMPSIRHQDVYS VDDIEGRMDEPKSCDKTHTCPPCPA PELLGGPSVFLFPPKPKDTLMISRT PEVTCVVVDVSHEDPEVKFNWYVDG VEVHNAKTKPREEQYNSTYRVVSVL TVLHQDWLNGKEYKCKVSNKALPAP IEKTISKAKGQPREPQVYTLPPSRE EMTKNQVSLTCLVKGFYPSDIAVEW ESNGQPENNYKTTPPVLDSDGSFFL YSKLTVDKSRWQQGNVFSCSVMHEA LHNHYTQKSLSLSPGK
• Endotoxin: Endotoxin level is <0.1 ng/µg of protein (<1EU/µg).
• Purity: >95% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 µg/ml. Dissolve the lyophilized protein in 1X PBS. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Gene Information

• Gene Name: TREML2 triggering receptor expressed on myeloid cells-like 2 [ Homo sapiens ]
• Official Symbol: TREML2
• Synonyms: TREML2; triggering receptor expressed on myeloid cells-like 2; C6orf76, chromosome 6 open reading frame 76; trem-like transcript 2 protein; dJ238O23.1; FLJ13693; TLT2; TREM like transcript 2; triggering receptor expressed on myeloid cells-like protein 2; TLT-2; C6orf76; MGC149715; MGC149716
• Gene ID: 79865
• mRNA Refseq: NM_024807
• Protein Refseq: NP_079083
• MIM: 609715
• UniProt ID: Q5T2D2