UBE2B Protein, ubiquitin-conjugating enzyme E2B

UBE2B

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UBE2B

Official Full Name ubiquitin-conjugating enzyme E2B
Background The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is required for post-replicative DNA damage repair. Its protein sequence is 100% identical to the mouse, rat, and rabbit homologs, which indicates that this enzyme is highly conserved in eukaryotic evolution.
Synonyms UBE2B; ubiquitin-conjugating enzyme E2B; ubiquitin conjugating enzyme E2B (RAD6 homolog); ubiquitin-conjugating enzyme E2 B; HHR6B; RAD6B; UBC2; E2 protein; RAD6 homolog B; ubiquitin-protein ligase B; ubiquitin carrier protein B; ubiquitin-conjugating enz
    • Species :
    • Cynomolgus Monkey
    • Human
    • Mouse
    • Rat
    • Rhesus Macaque
    • Zebrafish
    • Source :
    • E.coli
    • HEK293
    • Mammalian Cell
    • Tag :
    • GST
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human UBE2B-07H Recombinant Human Ubiquitin Conjugating Enzyme E2B E.coli N/A
    Human UBE2B-31450TH Recombinant Human UBE2B protein E.coli N/A
    Human UBE2B-3526H Recombinant Human UBE2B, GST-tagged E.coli GST
    Human UBE2B-531H Recombinant Human UBE2B Protein, His-tagged E.coli His
    Human UBE2B-55H Recombinant Human UBE2B, His-tagged E.coli His
    Human UBE2B-593HCL Recombinant Human UBE2B 293 Cell Lysate HEK293 N/A
    Human UBE2B-615H Recombinant Human UBE2B Protein, His-tagged HEK293 His
    Human UBE2B-616H Recombinant Human UBE2B Protein E.coli N/A
    Mouse UBE2B-1006M Recombinant Mouse UBE2B Protein E.coli N/A
    Rat UBE2B-6393R Recombinant Rat UBE2B Protein Mammalian Cell His
    Cynomolgus Monkey UBE2B-1071C Recombinant Cynomolgus UBE2B Protein, His-tagged Mammalian Cell His
    Rhesus Macaque UBE2B-5054R Recombinant Rhesus monkey UBE2B Protein, His-tagged Mammalian Cell His
    Zebrafish UBE2B-843Z Recombinant Zebrafish UBE2B Mammalian Cell His

    UBE2B involved in several pathways and played different roles in them. We selected most pathways UBE2B participated on our site, such as Ubiquitin mediated proteolysis, which may be useful for your reference. Also, other proteins which involved in the same pathway with UBE2B were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Ubiquitin mediated proteolysis CDC27; UBR5; UBE2Z; DET1; UBE2KB; UBE2W; UBE2K; KEAP1; CDC34; ERCC8

    UBE2B has several biochemical functions, for example, ATP binding, protein binding, ubiquitin conjugating enzyme activity. Some of the functions are cooperated with other proteins, some of the functions could acted by UBE2B itself. We selected most functions UBE2B had, and list some proteins which have the same functions with UBE2B. You can find most of the proteins on our site.

    Function Related Protein
    ATP binding KALRN; MAP2K4A; MAPK12A; TNNI3K; PEX6; MSH3; TEP1; AK8; ATP1A4; UBE2L3
    protein binding EDNRA; TXNL4B; HSD17B14; MOB4; SHISA5; LYL1; NFYC; KISS1R; TBC1D19; PRDX1
    ubiquitin conjugating enzyme activity UBE2E2; UBE2D3; UBE2H; UBE2D2; UBE2J2; UBE2E3; UBE2T; UBE2G1; UBE2D2A; UBE2J1
    ubiquitin protein ligase activity ASB4; FLJ11011L; AKTIP; WWP1; HLTF; HERC3; ARIH1; RNF181; TRIM37; UBE2V1
    ubiquitin protein ligase binding CDC34A; GPI1; GRIK2; ERLIN2; CUL1A; UBXN1; PRKAR2B; UBE2NA; SMAD5; TRIB3
    ubiquitin-protein transferase activity RNF220; CDC23; TRIM17; HUWE1; TOPORS; ZYG11; TRIM37; RNF187; FBXO7; PEX12

    UBE2B has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with UBE2B here. Most of them are supplied by our site. Hope this information will be useful for your research of UBE2B.

    RNF20; RAD18; UBC; UNC119; CRMP1; UBR4; UBR3; UBR1; IRF7; MED31; RNF40; PEX2; CDC73

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