uqcrfs1
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  • Official Full Name
  • ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1
  • Synonyms
  • LRRGT00195
Cat.#:UQCRFS1-1207HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human UQCRFS1 Protein (79-274 aa), GST-tagged
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Cat.#:UQCRFS1-106HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human UQCRFS1 protein, GST-tagged
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Cat.#:UQCRFS1-388HTag:His
Source (Host):Mammalian CellsSpecies:Human
Product nameRecombinant Human UQCRFS1
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Cat.#:UQCRFS1-6459RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat UQCRFS1 Protein
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Cat.#:UQCRFS1-1278CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken UQCRFS1
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Cat.#:UQCRFS1-5973ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish UQCRFS1
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Cat.#:UQCRFS1-725HCLTag:N/A
Source (Host):HEK293Species:Human
Product nameRecombinant Human UQCRFS1 lysate
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Involved Pathway

UQCRFS1 involved in several pathways and played different roles in them. We selected most pathways UQCRFS1 participated on our site, such as Oxidative phosphorylation, Metabolic pathways, Cardiac muscle contraction, which may be useful for your reference. Also, other proteins which involved in the same pathway with UQCRFS1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Oxidative phosphorylation
ATP6V1A; NDUFA3; ATP6V0D2; NDUFB8; COX6B2; NDUFAB1A; ATP6V0C; NDUFA7; ATP12A; ATP6AP1
Metabolic pathways
LIPCA; FPGT; ALPPL2; AOX1; BPNT1; AK8; PLA2G12A; UGT1A6B; HSD3B4; GALCB
Cardiac muscle contraction
CACNA2D3; MYL4; COX8C; TPM4A; CACNG3; UQCR10; MYL2B; ATP1A1; TPM4B; COX7B2
Non-alcoholic fatty liver disease (NAFLD)
MAP3K11; COX7A1; NDUFS1; KCNA3; MAP3K5; IRS1; NDUFB8; UQCRC2; UQCRH; NDUFA10
Alzheimers disease
NDUFA2; NDUFB3; CASP12; ATP2A3; SDHC; SNCA; CASP8; SDHB; NDUFA10; ADAM10
Parkinsons disease
NDUFB7; NDUFA12; NDUFS6; COX7B2; UQCR10; NDUFA7; NDUFC2; UBA7; UBE2J2; COX5A
Huntingtons disease
POLR2C; UQCRC2; COX6A2; MT-ATP6; PLCB4; ATP5C1; SOD1; COX7A2L; NDUFA8; POLR2E

Protein Function

UQCRFS1 has several biochemical functions, for example, 2 iron, 2 sulfur cluster binding, metal ion binding, protein complex binding. Some of the functions are cooperated with other proteins, some of the functions could acted by UQCRFS1 itself. We selected most functions UQCRFS1 had, and list some proteins which have the same functions with UQCRFS1. You can find most of the proteins on our site.
Function
Related Protein
Function 2 iron, 2 sulfur cluster binding
Related Protein CISD2; GLRX2; ISCUB; CISD1; FXN; AIFM3; CIAPIN1; CMAH; XDH; CISD3
Function metal ion binding
Related Protein BCO2; MAT1A; CECR1A; SALL1; ZNF865; LHX2B; RIOK2; TAX1BP1; NGLY1; EXTL2
Function protein complex binding
Related Protein ITPR1; NCOA1; TG; AKAP5; TWF1; RARB; CTSL2; RNF40; OTOF; ERCC8
Function ubiquinol-cytochrome-c reductase activity
Related Protein UQCR11; UQCRFS1; UQCRQ; UQCRC1; UQCRH; UQCR10

Interacting Protein

UQCRFS1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with UQCRFS1 here. Most of them are supplied by our site. Hope this information will be useful for your research of UQCRFS1.
UQCRC1; VHL; SOX5; RELB; NDUFS5; MYC; COX6C; Rab5c; ICT1; NDUFA9; Rmdn3; NDUFA11; NDUFA13; VAPA; NDUFA12; GOLT1B

UQCRFS1 Related Articles

Dato, S; Soerensen, M; et al. Contribution of genetic polymorphisms on functional status at very old age: A gene-based analysis of 38 genes (311 SNPs) in the oxidative stress pathway. EXPERIMENTAL GERONTOLOGY 52:23-29(2014).
Sanchez, E; Lobo, T; et al. LYRM7/MZM1L is a UQCRFS1 chaperone involved in the last steps of mitochondrial Complex III assembly in human cells. BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS 1827:285-293(2013).