usp13
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  • Official Full Name
  • ubiquitin specific peptidase 13 (isopeptidase T-3)
  • Background
  • Ubiquitin carboxyl-terminal hydrolase 13 is an enzyme that in humans is encoded by the USP13 gene.
  • Synonyms
  • USP13; ubiquitin specific peptidase 13 (isopeptidase T-3); ubiquitin specific protease 13 (isopeptidase T 3); ubiquitin carboxyl-terminal hydrolase 13; IsoT 3; isopeptidase T-3; ubiquitin thioesterase 13; deubiquitinating enzyme 13; ubiquitin thiolesteras
Cat.#:USP13-3616HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human USP13, GST-tagged
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Cat.#:USP13-17902MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse USP13 Protein
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Cat.#:USP13-5120RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey USP13 Protein, His-tagged
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Cat.#:USP13-5676ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish USP13
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Cat.#:USP13-472HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human USP13 293 Cell Lysate
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Protein Function

USP13 has several biochemical functions, for example, BAT3 complex binding, chaperone binding, cysteine-type endopeptidase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by USP13 itself. We selected most functions USP13 had, and list some proteins which have the same functions with USP13. You can find most of the proteins on our site.
Function
Related Protein
Function BAT3 complex binding
Related Protein USP13; AMFR; VCP; SGTA
Function chaperone binding
Related Protein PIH1D3; CXorf41; BAG2; TSACC; PARK2; PFDN6; AHSA1; TFRC; CP; TBCA
Function cysteine-type endopeptidase activity
Related Protein USP2A; ATG4C; CTLA2B; USP17L5; CTSS; CASP6L1; USP12A; CTSC; USP9; PDIA3
Function omega peptidase activity
Related Protein JOSD2; UCHL5; USP13; GGH; ATXN3; UCHL1; JOSD1; USP5; APEH; ATXN3L
Function proteasome binding
Related Protein PSMG1; USP14; PSMD14; UCHL5; BAG6; PSMF1; UBD; ID1; ADRM1; DNAJB2
Function protein binding
Related Protein SP2; TRIM43; DTNB; MAD2L2; HM13; PINX1; BCS1L; CKMT1; GATA3; ARNTL1A
Function ubiquitin binding
Related Protein KCNS1; UBXN2B; OTUB1A; RNF31; TOP2A; SMAD3; SHRPRBCK1R; KIF18A; HSPB1; TRP53INP2
Function ubiquitin protein ligase binding
Related Protein SNCAIP; SMAD6; BLZF1; MID1; AICDA; PPARGC1A; VCL; SPG20; GGN; RFFL
Function ubiquitin-like protein ligase binding
Related Protein DDRGK1; USP13; VCP; CDK5RAP3; CEBPB; TRIP4
Function ubiquitin-specific protease activity
Related Protein TNFAIP3; USP2A; USP17L5; USP45; OTUD1; FMNL3; USP9X; USP28; USP14; USP49
Function ubiquitin-specific protease activity involved in positive regulation of ERAD pathway
Related Protein USP13
Function zinc ion binding
Related Protein SIRT6; TRIM43A; TRIM105; CRIP1; TRIM44; Shh; ZCCHC12; PYGO1; SIVA1; TRIM61

Interacting Protein

USP13 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with USP13 here. Most of them are supplied by our site. Hope this information will be useful for your research of USP13.
SMC1A; SMC3; UBL4A; DLST; USP5; BAG6; ATXN3; OGDH; NEDD8; NPLOC4; UFD1L; FAF2; ITCH; KCTD10; CACYBP; CYLD; DIABLO; TCAF1

USP13 Related Articles

Xiang, SJ; Fang, JQ; et al. MicroRNA-135b regulates the stability of PTEN and promotes glycolysis by targeting USP13 in human colorectal cancers. ONCOLOGY REPORTS 33:1342-1348(2015).
Liu, YF; Soetandyo, N; et al. USP13 antagonizes gp78 to maintain functionality of a chaperone in ER-associated degradation. ELIFE 3:-(2014).