USP13 Protein, ubiquitin specific peptidase 13 (isopeptidase T-3)


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Official Full Name ubiquitin specific peptidase 13 (isopeptidase T-3)
Background Ubiquitin carboxyl-terminal hydrolase 13 is an enzyme that in humans is encoded by the USP13 gene.
Synonyms USP13; ubiquitin specific peptidase 13 (isopeptidase T-3); ubiquitin specific protease 13 (isopeptidase T 3); ubiquitin carboxyl-terminal hydrolase 13; IsoT 3; isopeptidase T-3; ubiquitin thioesterase 13; deubiquitinating enzyme 13; ubiquitin thiolesteras
    • Species :
    • Human
    • Mouse
    • Rhesus Macaque
    • Zebrafish
    • Source :
    • E.coli
    • HEK293
    • Mammalian Cell
    • Tag :
    • GST
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human USP13-3616H Recombinant Human USP13, GST-tagged E.coli GST
    Human USP13-472HCL Recombinant Human USP13 293 Cell Lysate HEK293 N/A
    Mouse USP13-17902M Recombinant Mouse USP13 Protein Mammalian Cell His
    Rhesus Macaque USP13-5120R Recombinant Rhesus monkey USP13 Protein, His-tagged Mammalian Cell His
    Zebrafish USP13-5676Z Recombinant Zebrafish USP13 Mammalian Cell His

    USP13 involved in several pathways and played different roles in them. We selected most pathways USP13 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with USP13 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein

    USP13 has several biochemical functions, for example, BAT3 complex binding, chaperone binding, cysteine-type endopeptidase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by USP13 itself. We selected most functions USP13 had, and list some proteins which have the same functions with USP13. You can find most of the proteins on our site.

    Function Related Protein
    BAT3 complex binding VCP; USP13; AMFR; SGTA
    chaperone binding TIMM9; PRNP; AHSA1; AHSA2; ATP1A1; CLU; DNAJA3A; SLC25A17; HSPD1; BAG2
    cysteine-type endopeptidase activity ATG4B; USP12; CASP14; CTSS; USP45; USP12A; USP24; ATG4D; CTSH; UCHL1
    omega peptidase activity GGH; APEH; JOSD2; UCHL1; USP13; UCHL5; USP5; ATXN3L; JOSD1; ATXN3
    proteasome binding DNAJB2; UBD; ADRM1; ID1; PSMD14; PSMF1; USP14; USP13; PSMG1; UCHL5
    protein binding POLD1; TMEM139; ANKS1A; RNF10; FAM104A; STX11; ITGA4; BCL2L1; FARS2; TRPC2
    ubiquitin binding TRP53INP2; VPS28; NBR1; USP5; SIRT2; OTUB2; UBE2N; UCHL1; VPS36; CRY2
    ubiquitin protein ligase binding UBE2NB; BAG5; DTX1; BECN1; UBXN1; UBE2NA; UBE2V2; UBE2K; MID1; ACVR1B
    ubiquitin-like protein ligase binding USP13; TRIP4; CDK5RAP3; CEBPB; DDRGK1; VCP
    ubiquitin-specific protease activity VCPIP1; USP31; USP47; ZRANB1; OTUD7A; OTUD7B; USP12A; OTUB2; OTUB1; USP17L2
    ubiquitin-specific protease activity involved in positive regulation of ERAD pathway USP13
    zinc ion binding PDZRN4; ZFP346; ZFAND2B; POLR3K; ZDHHC4; ZZEF1; ZDHHC18A; TOPORS; SREK1IP1; ZDHHC18

    USP13 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with USP13 here. Most of them are supplied by our site. Hope this information will be useful for your research of USP13.


    Xiang, SJ; Fang, JQ; et al. MicroRNA-135b regulates the stability of PTEN and promotes glycolysis by targeting USP13 in human colorectal cancers. ONCOLOGY REPORTS 33:1342-1348(2015).
    Liu, YF; Soetandyo, N; et al. USP13 antagonizes gp78 to maintain functionality of a chaperone in ER-associated degradation. ELIFE 3:-(2014).

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