vapa
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  • Official Full Name
  • VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa
  • Background
  • The protein encoded by this gene is a type IV membrane protein. It is present in the plasma membrane and intracellular vesicles. It may also be associated with the cytoskeleton. This protein may function in vesicle trafficking, membrane fusion, protein complex assembly and cell motility. Alternative splicing occurs at this locus and two transcript variants encoding distinct isoforms have been identified.
  • Synonyms
  • VAPA; VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa; VAMP (vesicle associated membrane protein) associated protein A (33kD); vesicle-associated membrane protein-associated protein A; hVAP 33; VAP A; 33 kDa Vamp-associated protein; VAMP A; VAMP associated protein A; VAMP-A; VAMP-associated protein A; VAP 33; VAP-33; VAP-A; VAP33; VAPA_HUMAN; Vesicle associated membrane protein associated protein A; OTTHUMP00000162362; OTTHUMP00000162363; hVAP-33
Cat.#:VAPA-287HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human VAPA Protein, His-tagged
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Cat.#:VAPA-1846HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human VAPA, His-tagged
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Cat.#:VAPA-30991THTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human VAPA, His-tagged
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Cat.#:VAPA-30992THTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human VAPA, His-tagged
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Cat.#:VAPA-3645HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human VAPA, GST-tagged
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Cat.#:VAPA-17979MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse VAPA Protein
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Cat.#:VAPA-6498RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat VAPA Protein
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Cat.#:VAPA-3626CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken VAPA
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Cat.#:VAPA-10287ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish VAPA
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Cat.#:VAPA-431HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human VAPA 293 Cell Lysate
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Involved Pathway

VAPA involved in several pathways and played different roles in them. We selected most pathways VAPA participated on our site, such as Tight junction, which may be useful for your reference. Also, other proteins which involved in the same pathway with VAPA were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Tight junction
PRKCHA; MYH3; MAGI1; NRAS; MYH9A; MYH8; RRAS2; RAB3B; ACTB2; SYMPK

Protein Function

VAPA has several biochemical functions, for example, FFAT motif binding, microtubule binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by VAPA itself. We selected most functions VAPA had, and list some proteins which have the same functions with VAPA. You can find most of the proteins on our site.
Function
Related Protein
Function FFAT motif binding
Related Protein VAPA; VAPB; VAPAL
Function microtubule binding
Related Protein MAPRE1A; SGIP1; CHP; KLC3; PLK1; MARK4; GAS2L3; KIF17; SKA2; MAP2
Function protein binding
Related Protein COLQ; DNMT3B; CDK13; ZNF398; RPH3A; CFH; S100A13; ANKRD32; UPF1; NTM
Function protein domain specific binding
Related Protein CHMP1B; STMN3; MYO7A; ARL1; RAP2B; NR0B1; HIST1H4A; WNT5A; E2F4; DDC
Function protein heterodimerization activity
Related Protein ITGB1; NEFH; BCL2; ADD1; KCNN1; HIST1H4I; HIST1H2BA; TAF4B; UGT1A2; SIM2
Function signal transducer activity
Related Protein FAS; ADORA2AA; TAAR14D; TNK1; MALT1; GULP1; V2RH14; CXCR3.2; TAS2R134; GNAQ

Interacting Protein

VAPA has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with VAPA here. Most of them are supplied by our site. Hope this information will be useful for your research of VAPA.
p27958-pro_0000037576; p27958-pro_0000037577; q03463-pro_0000278740; YIF1A; q03463-pro_0000278741

VAPA Related Articles

Deidda, I; Galizzi, G; et al. Expression of vesicle-associated membrane-protein-associated protein B cleavage products in peripheral blood leukocytes and cerebrospinal fluid of patients with sporadic amyotrophic lateral sclerosis. EUROPEAN JOURNAL OF NEUROLOGY 21:478-485(2014).
Vanden Bergh, P; Burr, SE; et al. Antigens of the type-three secretion system of Aeromonas salmonicida subsp salmonicida prevent protective immunity in rainbow trout. VACCINE 31:5256-5261(2013).