vav1
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  • Official Full Name
  • VAV1 vav 1 guanine nucleotide exchange factor
  • Synonyms
  • VAV1; vav 1 guanine nucleotide exchange factor; VAV, vav 1 oncogene; proto-oncogene vav; vav 1 oncogene; VAV;
Cat.#:VAV1-411HTag:His|GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human VAV1 Protein, His/GST-tagged
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Cat.#:Vav1-412MTag:His
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Vav1 Protein, His-tagged
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Cat.#:VAV1-163HTag:GST
Source (Host):Sf 9 Insect cellsSpecies:Human
Product nameRecombinant Human VAV1, GST-tagged
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Cat.#:VAV1-341HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human vav 1 guanine nucleotide exchange factor, His-tagged
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Cat.#:VAV1-3652HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human VAV1, His-tagged
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Cat.#:VAV1-423HCLTag:N/A
Source (Host):Species:Human
Product nameRecombinant Human VAV1 293 Cell Lysate
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Involved Pathway

VAV1 involved in several pathways and played different roles in them. We selected most pathways VAV1 participated on our site, such as cAMP signaling pathway, Chemokine signaling pathway, Focal adhesion, which may be useful for your reference. Also, other proteins which involved in the same pathway with VAV1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
cAMP signaling pathway
Adcy4; HTR6; CNGA3; RAP1A; ATP2A2; FXYD2; BDNF; ACOX3; ATP1B2; GRIN2D
Chemokine signaling pathway
RLN1; XCR1; PIK3R2; CCL20; CCR5; SHC1; CCL5; PLCB2; PIK3R1; WAS
Focal adhesion
PRKCG; MYLK; MYL9B; ITGB3; TNK1; IBSP; BCL2A; MYL12.2; GRB2B; PXN
Natural killer cell mediated cytotoxicity
RAET1L; BID; PPP3CB; KLRC1; MAPK1; PPP3CC; ZAP70; PIK3CA; KIR2DS4; VAV3
T cell receptor signaling pathway
CARD11; PIK3R3; NFATC1; DLG1; PDPK1; PDCD1; TEC; PAK3; OXSR1A; CD4
B cell receptor signaling pathway
INPP5D; PIK3AP1; NFATC1; GRB2; NFKBIE; PPP3R2; MAPK1; RAC1; Cd79a, Cd79b; SLA2
Fc epsilon RI signaling pathway
MS4A2; PLA2G4C; HRAS; IL3; PLCG1; AKT1; MAP2K4; PLA2G4D; PIK3CD; PLA2G4F
Fc gamma R-mediated phagocytosis
GAB2; PLA2G4D; PAK1; PLA2G4A; FCGR1A; DOCK2; LIMK1; BIN1; HCK; PTPRC
Leukocyte transendothelial migration
CLDN4; ITGAM; GNAI1; CLDN23; PTPN11; PIK3R5; PIK3CG; RASSF5; PIK3CA; CLDN20
Regulation of actin cytoskeleton
ITGA3B; EZR; FN1; EZRB; ITGB4; PIP5K1BA; PIK3R3; APC2; MYH10; CYFIP2

Protein Function

VAV1 has several biochemical functions, for example, Rac guanyl-nucleotide exchange factor activity, guanyl-nucleotide exchange factor activity, metal ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by VAV1 itself. We selected most functions VAV1 had, and list some proteins which have the same functions with VAV1. You can find most of the proteins on our site.
Function
Related Protein
Function Rac guanyl-nucleotide exchange factor activity
Related Protein DOCK2; VAV1; PREX2; FARP1; ARHGEF2; ALS2; SPATA13; VAV3; FARP2; ARHGEF4
Function guanyl-nucleotide exchange factor activity
Related Protein DOCK4; KNDC1; VAV3B; TIAM2; FNIP1; TRIOA; DENND4B; DOCK8; PLCE1; RANGRF
Function metal ion binding
Related Protein ZNF143A; ITGAM; CYP2AD2; KLF14; EXO5; RRM2; ZNF189; ACSM4; THAP10; KLF13
Function protein binding
Related Protein IL1A; TNFAIP8; UCP3; SFRP1; SP140; BTN2A2; RCC2; MRPL41; TRAIP; CRTAC1
Function transcription factor activity, sequence-specific DNA binding
Related Protein KAT7B; MTA1; NFE2L1B; MYCLB; ZNF436; FOXL2; SP140; ZNF613; ZFP30; RBPJL

Interacting Protein

VAV1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with VAV1 here. Most of them are supplied by our site. Hope this information will be useful for your research of VAV1.
SH3BP2; LCP2; ABL1