ABCB7
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Official Full Name
ATP-binding cassette, sub-family B (MDR/TAP), member 7
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Overview
The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance as well as antigen presentation. This gene encodes a half-transporter involved in the transport of heme from the mitochondria to the cytosol. With iron/sulfur cluster precursors as its substrates, this protein may play a role in metal homeostasis. Mutations in this gene have been associated with mitochondrial iron accumulation and isodicentric (X)(q13) and sideroblastic anemia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2012] -
Synonyms
ABCB7; ATP-binding cassette, sub-family B (MDR/TAP), member 7; ABC7; ASAT; Atm1p; EST140535; ATP-binding cassette sub-family B member 7, mitochondrial; ABC transporter 7 protein; ATP-binding cassette transporter 7;
- Recombinant Proteins
- Protein Pre-coupled Magnetic Beads
- Human
- Mouse
- Mus musculus (Mouse)
- Rat
- Rattus norvegicus (Rat)
- E.coli
- E.coli expression system
- HEK293
- In Vitro Cell Free System
- Mammalian Cell
- Wheat Germ
- GST
- His
- His (Fc)
- Avi
- His|T7
- N
- Tag
- Free
- Involved Pathway
- Protein Function
- Interacting Protein
- ABCB7 Related Articles
ABCB7 involved in several pathways and played different roles in them. We selected most pathways ABCB7 participated on our site, such as ABC transporters, which may be useful for your reference. Also, other proteins which involved in the same pathway with ABCB7 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| ABC transporters | ABCB9;ABCA1B;SUR2A;ABCB10;ABCB7;ABCC3;ABCC9;ABCB6;ABCC2 |
ABCB7 has several biochemical functions, for example, ATP binding, ATPase activity, coupled to transmembrane movement of substances, heme transporter activity. Some of the functions are cooperated with other proteins, some of the functions could acted by ABCB7 itself. We selected most functions ABCB7 had, and list some proteins which have the same functions with ABCB7. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| ATP binding | SLK;ATP2C2;ACTB;GSS;P2RX5;ADCY7;DDX53;GUCY2F;OAS2 |
| ATPase activity, coupled to transmembrane movement of substances | ABCC6;ABCA3;ABCB3L1;ABCG5;ABCB5;ABCB1A;ABCC1;ABCB4;ABCA7 |
| heme transporter activity | MFSD7B;SLC48A1;MFSD7C;SLC48A1A;FLVCR1;SLC48A1B;HPX;ABCB7;HRG-1 |
ABCB7 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ABCB7 here. Most of them are supplied by our site. Hope this information will be useful for your research of ABCB7.
Kcnk1; MYC
- Q&As
- Reviews
Q&As (10)
Ask a questionYou can communicate with our technical experts who can help you choose the right product.
Yes, this result is caused by post-translational modification, post-translational cleavage, splice variants, etc.
You can communicate with us about the specific customization requirements, and then we will provide you with product price information.
Our recombinant protein products are accompanied by detailed product instructions, and you can contact our technical experts at any time if you have any questions after receiving the product.
Two of the ABCB7 protein products we provide require custom production, and the prices vary according to custom needs, but we can provide you with price information for the other 5 protein products.
Yes, we can customize recombinant protein products with different purity.
There is information in our product manuals, or you can ask our experts about it.
Our customers purchased ABCB7 for ELISA and obtained satisfactory experimental results.
We will send you product price information.
Yes, we offer ABCB7 protein ready for western blotting.
Customer Reviews (4)
Write a reviewGreat protein, works great for WB.
The content of the product manual is very detailed, which provides help for the use of protein products.
High protein purity, fast delivery.
The technicians answered my questions in a timely manner and provided me with some professional advice.
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