ABI1
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Official Full Name
abl-interactor 1
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Overview
Abelson interactor 1 (ABI1) is widely expressed with highest expression in brain. ABI1 in participation with EPS8 and SOS1?is involved in the transduction of signals from Ras to Rac. At least 10 isoforms are produced by alternative splicing. -
Synonyms
ABI1; abl-interactor 1; spectrin SH3 domain binding protein 1 , SSH3BP1; abl interactor 1; ABI 1; E3B1; Abelson interactor 1; nap1 binding protein; abl-binding protein 4; interactor protein AblBP4; Abl-interactor protein 1 long; eps8 SH3 domain-binding pr;
- Recombinant Proteins
- Cell & Tissue Lysates
- Chicken
- Human
- Mouse
- E.coli
- HEK293
- HEK293T
- In Vitro Cell Free System
- Mammalian Cell
- Wheat Germ
- GST
- His
- T7
- Myc
- DDK
- Non
- Involved Pathway
- Protein Function
- Interacting Protein
ABI1 involved in several pathways and played different roles in them. We selected most pathways ABI1 participated on our site, such as E-cadherin signaling in the nascent adherens junction, EGFR1 Signaling Pathway, ErbB1 downstream signaling, which may be useful for your reference. Also, other proteins which involved in the same pathway with ABI1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| E-cadherin signaling in the nascent adherens junction | CTNND1;ABI1;NCKAP1;WASF2;KLHL20 |
| EGFR1 Signaling Pathway | GRB14;RBBP7;DOK2;PITPNAA;SH3BGRL;DNM1;KRT7;STXBP1A;ELF3 |
| ErbB1 downstream signaling | BAIAP2;NCKAP1;ABI1;ACTR3;MAP3K2;EPS8;EGR1;ARF4;ACTR2 |
| Fcgamma receptor (FCGR) dependent phagocytosis | PLD4;ARPC1A;BAIAP2;ABI1B;NCKAP1;WIPF2;PPAPDC1A;PPAPDC1B;ABI1 |
| Immune System | BFB;ATG7;NLRP4C;RNF144B;PLD4;SRMS;ASB7;AP1B1;BTLA |
| Innate Immune System | NLRC5;PELI3;WIPF3;POLR3GLA;TREM1;CTSLL;PCBP2;PLD4;DHX9 |
| RAC1 signaling pathway | ABI2;IQGAP3;NOXA1;BAIAP2;NOXO1;ABI1;NCKAP1;RACGAP1 |
| RHO GTPase Effectors | ACTR2B;KLC3;SPC25;NCKAP1;TAX1BP3;DIAPH1;ZWILCH;SPC24;AHCTF1 |
ABI1 has several biochemical functions, for example, cytoskeletal protein binding, protein binding, protein complex binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ABI1 itself. We selected most functions ABI1 had, and list some proteins which have the same functions with ABI1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| cytoskeletal protein binding | EZRB;PKD2;EZRA;EPB41B;FRMD3;EPB41L3B;ANXA2B;MYLIP;CAPN1 |
| protein binding | SOX-2;HIST1H4E;CLDN18;SEPHS1;HSFX1;TK1;ILF2;CNOT1;GRIN2C |
| protein complex binding | PCSK2;FBN1;EPCAM;CDK2;COG2;VDAC1;RBX1;TELO2;Ctsl |
| protein tyrosine kinase activator activity | GAS6;ABI1;PAK2;ABI1A;NRG1;AFAP1L2;ABI1B;GHRL;Cd24a |
ABI1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ABI1 here. Most of them are supplied by our site. Hope this information will be useful for your research of ABI1.
ABL1; NCKAP1; WASF2
- Reviews
- Q&As
Customer Reviews (2)
Write a reviewRecombinant chicken ABI1 has high purity and good immunogenicity, and the experimental results are very satisfactory.
The technical support experts at Creative BioMart customized the ABI1 protein with a specific expression system and fusion tag for me.
Q&As (5)
Ask a questionSome of our products contain cleavage sites between the tag and the target protein. Please consult our experts for specific product information.
Sure, Creative BioMart supports custom protein production services.
We provide various expression systems, including E. coli, wheat germ, in vitro cell free system, and mammalian cell expression systems.
ABI1 may play a role in regulating EGF-induced activation of the Erk pathway and, together with EPS8, is involved in signal transduction from Ras to Rac.
Yes, our recombinant ABI1 protein can be used as a variety of applications based on the antigen-antibody reaction.
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