ABI1

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ABI1

Official Full Name abl-interactor 1
Background Abelson interactor 1 (ABI1) is widely expressed with highest expression in brain. ABI1 in participation with EPS8 and SOS1?is involved in the transduction of signals from Ras to Rac. At least 10 isoforms are produced by alternative splicing.
Synonyms ABI1; abl-interactor 1; spectrin SH3 domain binding protein 1 , SSH3BP1; abl interactor 1; ABI 1; E3B1; Abelson interactor 1; nap1 binding protein; abl-binding protein 4; interactor protein AblBP4; Abl-interactor protein 1 long; eps8 SH3 domain-binding pr
    • Species :
    • Chicken
    • Human
    • Mouse
    • Source :
    • E.coli
    • HEK293
    • HEK293T
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • T7
    • MYC/DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human ABI1-085H Recombinant Human ABI1 Protein, GST-Tagged Wheat Germ GST
    Human ABI1-086H Recombinant Human ABI1 Protein, GST-Tagged Wheat Germ GST
    Human ABI1-1704H Recombinant Human ABI1 protein, His & T7-tagged E.coli His/T7
    Human ABI1-1779H Recombinant Human ABI1 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
    Human ABI1-4188H Recombinant Human ABI1 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
    Human ABI1-9128HCL Recombinant Human ABI1 293 Cell Lysate HEK293 N/A
    Human ABI1-9129HCL Recombinant Human ABI1 293 Cell Lysate HEK293 N/A
    Human ABI1-9246H Recombinant Human ABI1, GST-tagged E.coli GST
    Mouse Abi1-501M Recombinant Mouse Abi1 Protein, MYC/DDK-tagged HEK293T MYC/DDK
    Chicken ABI1-3344C Recombinant Chicken ABI1 Mammalian Cell His

    ABI1 involved in several pathways and played different roles in them. We selected most pathways ABI1 participated on our site, such as E-cadherin signaling in the nascent adherens junction, EGFR1 Signaling Pathway, ErbB1 downstream signaling, which may be useful for your reference. Also, other proteins which involved in the same pathway with ABI1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    E-cadherin signaling in the nascent adherens junction CTNND1; NCKAP1; WASF2; ABI1; KLHL20
    EGFR1 Signaling Pathway PTPN12; RGS5B; ERRFI1; RALBP1; CRKL; ABI1B; ZPR1; SH3BGRL; JUND; RBB4L
    ErbB1 downstream signaling ACTR3; NCKAP1; ACTR2; MAP3K2; ARF4; WASF2; BAIAP2; EPS8; EGR1; ABI1
    Fcgamma receptor (FCGR) dependent phagocytosis PLD4; PPAPDC1A; WIPF3; ACTR2; ABI1A; IgG3; ACTR3; MYO9B; WIPF2; WASF2
    Immune System GBP2; ERAP1; RNF135; RAPGEF4; ASB7; SIGLEC9; ASB11; TRIM41; CMTM2A; CTSD
    Innate Immune System POLR3G; CHST13; CFHL1; DEFA3; DEFB4B; BTR16; BTR09; DEFB4A; DEFA1; NLRP4B
    RAC1 signaling pathway NOXA1; BAIAP2; NCKAP1; ABI1; RACGAP1; IQGAP3; NOXO1; ABI2
    RHO GTPase Effectors SGOL2; KNTC1; ERCC6L; NDEL1A; BAIAP2; ABI2; NCKIPSD; RCC2; WASF3; ZWINT

    ABI1 has several biochemical functions, for example, cytoskeletal protein binding, protein binding, protein complex binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ABI1 itself. We selected most functions ABI1 had, and list some proteins which have the same functions with ABI1. You can find most of the proteins on our site.

    Function Related Protein
    cytoskeletal protein binding ALDOB; PACSIN2; PKD2; ANXA2; MYLIP; MYPN; SLC8A1; TPM1; B4GALT1; PDLIM3
    protein binding RPIA; MC3R; KRTAP5-6; C1orf50; IL-8; CPEB4; NDRG4; NIPBL; ECT2; MRPS6
    protein complex binding SKIL; SH2B3; LRP1; NASP; PRKACA; TMED10; EP300; PFKP; NFKBIA; PTPRF
    protein tyrosine kinase activator activity GHRL; PAK2; AFAP1L2; ABI1B; ABI1; GAS6; ABI1A; ABI3A; CD24; ERCC6

    ABI1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ABI1 here. Most of them are supplied by our site. Hope this information will be useful for your research of ABI1.

    ABL1; NCKAP1; WASF2

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