ABI2
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Official Full Name
abl-interactor 2 -
Overview
Abl interactor 2 also known as Abelson interactor 2 (Abi-2) is a protein that in humans is encoded by the ABI2 gene. -
Synonyms
ABI2;abl-interactor 2;abl interactor 2;ABI 2;ABI2B;AblBP3;AIP 1;argBPIA;SSH3BP2;Abelson interactor 2;Abl binding protein 3;Abl interacting protein 1 (SH3 containing protein);Abl interactor protein 2b;Arg binding protein 1;Arg protein tyrosine kinase binding protein;ArgBP1;ArgBPIB;OTTHUMP00000163783;OTTHUMP00000163784;OTTHUMP00000206182;OTTHUMP00000206183;OTTHUMP00000206184;OTTHUMP00000206185;abl-binding protein 3;arg-binding protein 1;abl-interactor protein 2b;arg protein tyrosine kinase-binding protein;abl-interacting protein 1 (SH3-containing protein);ABI-2;AIP-1
Recombinant Proteins
- Human
- Mouse
- E.coli
- Mammalian Cells
- E.Coli/Yeast
- HEK293
- In Vitro Cell Free System
- GST
- His
- Non
- DDK
- Myc
- Avi
- Fc
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| ABI2-9247H | Recombinant Human ABI2 protein, GST-tagged | E.coli | Human | GST | 1-275 aa | |
| SPP1-7901D | Recombinant Dog SPP1 protein, His-tagged | E.coli | Human | His | Ile7~Ser232 | |
| ABI2-1138M | Recombinant Mouse ABI2 Protein | Mammalian Cells | Mouse | His |
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| Abi2-3041M | Recombinant Mouse Abi2, His-tagged | E.Coli/Yeast | Mouse | His | 487 |
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| ABI2-9127HCL | Recombinant Human ABI2 293 Cell Lysate | HEK293 | Human | Non |
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| Abi2-1475M | Recombinant Mouse Abi2 Protein, Myc/DDK-tagged | HEK293 | Mouse | DDK&Myc |
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| ABI2-220M | Recombinant Mouse ABI2 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | Avi&Fc&His |
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| ABI2-220M-B | Recombinant Mouse ABI2 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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| ABI2-3532H | Recombinant Human ABI2 protein, His-tagged | E.coli | Human | His | 1-275 aa |
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| ABI2-4266H | Recombinant Human ABI2 Protein, Myc/DDK-tagged, C13 and N15-labeled | HEK293 | Human | DDK&Myc |
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| ABI2-891HF | Recombinant Full Length Human ABI2 Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 475 amino acids |
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Involved Pathway
ABI2 involved in several pathways and played different roles in them. We selected most pathways ABI2 participated on our site, such as Fcgamma receptor (FCGR) dependent phagocytosis,Immune System,Innate Immune System, which may be useful for your reference. Also, other proteins which involved in the same pathway with ABI2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| RHO GTPases Activate WASPs and WAVEs | WASF3,NCKIPSD,WIPF2,ABI1B,WIPF3,ABI1A |
| Immune System | CD200R2,POLR3F,DCTN6,UFL1,CD160,TRIM46,UBA5,POLR3GLA,IRF4,UBR1 |
| RAC1 signaling pathway | NCKAP1,IQGAP3,BAIAP2,RACGAP1,NOXA1,ABI1,NOXO1 |
| RHO GTPase Effectors | NDEL1B,NOXO1,MIS12,WIPF3,KDM4C,NUF2,TAX1BP3,FMNL2,SKA2,LIN7B |
| Fcgamma receptor (FCGR) dependent phagocytosis | ARPC1A,WIPF3,ACTR3,WASF2,NCKIPSD,PLD4,WIPF2,ACTR2,BAIAP2,NCKAP1 |
| Regulation of actin cytoskeleton | ITGB7,FGF19,CYFIP2,PIP5K1AA,KRAS,ARHGEF1,BDKRB2,APC2,MYLPFB,FGF13A |
| Innate Immune System | HERC5,WIPF2,WASF3,CASP4,HBL3,CD300LB,DEFB106A,ABI1B,ALCAMB,TAX1BP1 |
Protein Function
ABI2 has several biochemical functions, for example, DNA binding,contributes_to Rac GTPase binding,SH3 domain binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ABI2 itself. We selected most functions ABI2 had, and list some proteins which have the same functions with ABI2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| kinase binding | RPS3,BARD1,RASGRP3,DGKQ,BTG1,PTPN22,MOBKL1A,DLG1,PPP2R5A,ATF5 |
| SH3 domain binding | ARHGAP17,NCKIPSD,CTTNBP2,CYBA,PARK2,QK,SIRPA,INPP5J,CD3E,GRB2 |
| cytoskeletal adaptor activity | NCK2,SORBS2,BIN3,BAIAP2L1,ANK1,BAIAP2L1A,GAS2L2,COX4I2,BAIAP2L1B,GAS2L1 |
| ubiquitin protein ligase binding | OTUB1,UBE2L3,PIAS1,TRIM28,CALR,MID1,TMEM189,AXIN1,BLZF1,FAF1 |
| proline-rich region binding | RABAC1,PRPF40A,TCERG1,PFN1,ITSN1,CCND1,WBP4,FAM59A,BAIAP2L1,ABL1 |
| protein binding | TMSB4X,PKP4,PHF19,KDRL,APPBP2,AREG,VDR,LACTB2,TNPO3,FKBP3 |
| contributes_to Rac GTPase binding | WASF1,CYFIP1,BRK1,NCKAP1 |
| DNA binding | ZBTB12,LRRFIP1,TOPORS,ZSCAN18,SOX19A,PAX2B,POLR3H,ATRX,RECQL,SSBP3B |
| protein complex binding | KRT8,LCK,LRRC16A,C8A,ABI1,NCK2,SLC9A3R1,RBM10,PRMT5,GIT2 |
Interacting Protein
ABI2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ABI2 here. Most of them are supplied by our site. Hope this information will be useful for your research of ABI2.
NCK2;KRT15;IFT20;CCDC36;PCDH10
Resources
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References
- Hayashi, M; Inoue, S; et al. Immunohistochemical Detection of Blue Light-Induced Phosphorylation of the Plasma Membrane H+-ATPase in Stomatal Guard Cells. PLANT AND CELL PHYSIOLOGY 52:1238-1248(2011).
- Yoshida, R; Hobo, T; et al. ABA-activated SnRK2 protein kinase is required for dehydration stress signaling in Arabidopsis. PLANT AND CELL PHYSIOLOGY 43:1473-1483(2002).
