|Official Full Name||abl-interactor 2|
|Background||Abl interactor 2 also known as Abelson interactor 2 (Abi-2) is a protein that in humans is encoded by the ABI2 gene.|
|Synonyms||ABI2; abl-interactor 2; abl interactor 2; ABI 2; ABI2B; AblBP3; AIP 1; argBPIA; SSH3BP2; Abelson interactor 2; Abl binding protein 3; Abl interacting protein 1 (SH3 containing protein); Abl interactor protein 2b; Arg binding protein 1; Arg protein tyrosine kinase binding protein; ArgBP1; ArgBPIB; OTTHUMP00000163783; OTTHUMP00000163784; OTTHUMP00000206182; OTTHUMP00000206183; OTTHUMP00000206184; OTTHUMP00000206185; abl-binding protein 3; arg-binding protein 1; abl-interactor protein 2b; arg protein tyrosine kinase-binding protein; abl-interacting protein 1 (SH3-containing protein); ABI-2; AIP-1;|
|Species||Cat.#||Product name||Source (Host)||Tag||Protein Length||Price|
ABI2 involved in several pathways and played different roles in them. We selected most pathways ABI2 participated on our site, such as Fcgamma receptor (FCGR) dependent phagocytosis, Immune System, Innate Immune System, which may be useful for your reference. Also, other proteins which involved in the same pathway with ABI2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
|Pathway Name||Pathway Related Protein|
|Fcgamma receptor (FCGR) dependent phagocytosis||PPAPDC1B; ACTR2B; PLD4; WIPF2; ACTR3; BAIAP2; ARPC1A; MYO1C; ABI1; ABI1A|
|Immune System||WSB1; ASB9; KIFAP3; IFI16; CSH1; DEFB1; CD207; EIF4G2; OSBPL1A; PELI1|
|Innate Immune System||POLR3C; TNRC5; MASP2; PPAPDC1B; CD300E; DEFB119; TANK; DEFA1; UNC93B1; CD180|
|RAC1 signaling pathway||NOXO1; NCKAP1; RACGAP1; IQGAP3; NOXA1; ABI1; BAIAP2; ABI2|
|RHO GTPase Effectors||ACTR2B; ABI1B; NF2A; MKL1B; ZW10; ZWINT; MIS12; NDEL1A; NOXO1; RHOC|
|RHO GTPases Activate WASPs and WAVEs||WIPF2; ABI1B; ABI2; WASF3; ABI1A; WIPF3; NCKIPSD|
|Regulation of Actin Cytoskeleton||RHOAB; RHOAA; ACTB2; FGD3; FGF13A; ARPC5B; PIP4K2C; PIP5K1AA; HRASA; GNG12|
ABI2 has several biochemical functions, for example, DNA binding, contributes_to Rac GTPase binding, SH3 domain binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ABI2 itself. We selected most functions ABI2 had, and list some proteins which have the same functions with ABI2. You can find most of the proteins on our site.
|DNA binding||SMYD1; ENG2B; RFX1A; KDM5D; EVX2; ZBTB6; ANG; THAP11; RFX8; KIN|
|contributes_to Rac GTPase binding||NCKAP1; WASF1; ABI2; CYFIP1; BRK1|
|SH3 domain binding||NCF1; ADAM19; KHDRBS2; DRD4; FMN1; SGIP1; CRB3; BCAR1; DPYSL3; CYBA|
|cytoskeletal adaptor activity||NCK1; GAS2L2; BAIAP2L2; BAIAP2; BAIAP2L1; BAIAP2A; BAIAP2L2B; ANK1; ABI2; NCK2|
|kinase binding||CEBPA; PER3; CDC37; LDHB; PER1; PPP2R5A; BTG1; NTRK1; STX1A; CHP|
|proline-rich region binding||CSK; FAM59A; TCERG1; GHR; ITSN1; WBP4; GAREM; CCND1; PRPF40A; ABI2|
|protein binding||RPS16; GTF2H1; CCNB1; STRADB; PSPC1; RPS18; TYK2; KCNN4; CST9L; MBD1|
|protein complex binding||HNF1B; KAT2B; LCA5; RAP1B; PROS1; TULP2; PPP1R9B; DRD1; UGT1A6B; ATM|
|ubiquitin protein ligase binding||CUL9; PIAS2; TUBA1B; UBE2S; ARRB1; KCNQ3; UBE2V1; CUL4B; NEDD8; TRAF2|
ABI2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ABI2 here. Most of them are supplied by our site. Hope this information will be useful for your research of ABI2.
NCK2; KRT15; IFT20; CCDC36; PCDH10
Yes, our experts can customize protein expression according to your research needs.
His and GST tags are commonly used for affinity chromatography and are beneficial for improving protein solubility.
Disease variant and intellectual disability.
It is involved in host-virus interactions and neurogenesis.
Creative BioMart mainly provides custom protein services, and you can consult our scientists for specific project requirements.
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