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Official Full Name abl-interactor 2
Background Abl interactor 2 also known as Abelson interactor 2 (Abi-2) is a protein that in humans is encoded by the ABI2 gene.
Synonyms ABI2; abl-interactor 2; abl interactor 2; ABI 2; ABI2B; AblBP3; AIP 1; argBPIA; SSH3BP2; Abelson interactor 2; Abl binding protein 3; Abl interacting protein 1 (SH3 containing protein); Abl interactor protein 2b; Arg binding protein 1; Arg protein tyrosine kinase binding protein; ArgBP1; ArgBPIB; OTTHUMP00000163783; OTTHUMP00000163784; OTTHUMP00000206182; OTTHUMP00000206183; OTTHUMP00000206184; OTTHUMP00000206185; abl-binding protein 3; arg-binding protein 1; abl-interactor protein 2b; arg protein tyrosine kinase-binding protein; abl-interacting protein 1 (SH3-containing protein); ABI-2; AIP-1
    • Species :
    • Human
    • Mouse
    • Source :
    • E.coli
    • E.Coli or Yeast
    • HEK293
    • HEK293T
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • Myc/DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human ABI2-087H Recombinant Human ABI2 Protein, GST-Tagged Wheat Germ GST
    Human ABI2-4266H Recombinant Human ABI2 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
    Human ABI2-9127HCL Recombinant Human ABI2 293 Cell Lysate HEK293 N/A
    Human ABI2-9247H Recombinant Human ABI2, GST-tagged E.coli GST
    Mouse ABI2-1138M Recombinant Mouse ABI2 Protein Mammalian Cell His
    Mouse Abi2-1475M Recombinant Mouse Abi2 Protein, Myc/DDK-tagged HEK293T Myc/DDK
    Mouse Abi2-3041M Recombinant Mouse Abi2, His-tagged E.Coli or Yeast His

    ABI2 involved in several pathways and played different roles in them. We selected most pathways ABI2 participated on our site, such as Fcgamma receptor (FCGR) dependent phagocytosis, Immune System, Innate Immune System, which may be useful for your reference. Also, other proteins which involved in the same pathway with ABI2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Fcgamma receptor (FCGR) dependent phagocytosis IgG3; DOCK1; PPAPDC1A; WASF3; WASF2; ABI1B; MYO1C; ARPC1A; ABI1; WIPF2
    Immune System RCA2.1; WASF2; FCN3; TRIM63; KIF2C; ASB14; DEFB116; DYNC1H1; ASB10; TXNIPA
    Innate Immune System ALCAMB; CD300LB; PPAPDC1A; DDX41; POLR3C; CLEC6A; C1rb; MAP3K8; LAT2; FCN2
    RAC1 signaling pathway ABI2; NOXA1; ABI1; NOXO1; IQGAP3; NCKAP1; BAIAP2; RACGAP1
    RHO GTPase Effectors WIPF3; KNTC1; NOXO1; SPC25; LIN7B; ROPN1; PMF1; BAIAP2; RCC2; TAX1BP3
    Regulation of Actin Cytoskeleton FGF18; DIAP1; VIL1; PIK3R5; MYLPFA; FGFR4; PTK2AB; RDX; PIK3R1; PIK3R3B

    ABI2 has several biochemical functions, for example, DNA binding, contributes_to Rac GTPase binding, SH3 domain binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ABI2 itself. We selected most functions ABI2 had, and list some proteins which have the same functions with ABI2. You can find most of the proteins on our site.

    Function Related Protein
    DNA binding ZBTB48; NR1D2A; ZSCAN10; GLI4; ZNF689; FLI1A; HIVEP2; MEIOB; PHC2; UBTFL1
    contributes_to Rac GTPase binding NCKAP1; CYFIP1; ABI2; BRK1; WASF1
    SH3 domain binding RAD9A; LANCL1; ADAM19; PARK2; ELMO1; ADAM15; PLSCR4; FMNL3; CIT; ARHGAP6
    cytoskeletal adaptor activity NCK1; ABI2; GAS2L1; BICD1; BAIAP2L2B; BAIAP2A; BAIAP2L1; GAS2L2; BAIAP2L1B; SORBS2
    kinase binding TRADD; HSP90AB1; STUB1; PRPSAP1; UBQLN1; CHP1; MOB4; HAP1; C2orf44; PARK7
    proline-rich region binding WBP4; GAREM; NEDD4; BAIAP2L1; CYLD; CSK; ABL1; ABI2; BAIAP2; APBB1
    protein binding ZFYVE20; GOLSYN; SREK1; PIGK; NAV1; NEDD4; MYBPC1; AMBP; GDF2; RDH12
    protein complex binding SLC27A5; BAX; VHLL; KRAS; OTOF; ANKRD32; WASF2; ATM; PPP2R2A; GNB4
    ubiquitin protein ligase binding JKAMP; PRKACA; ARIH1; ABI2; UBE2J1; MFN2; CUL1; UBE2Z; HSPD1; BCL2

    ABI2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ABI2 here. Most of them are supplied by our site. Hope this information will be useful for your research of ABI2.

    NCK2; KRT15; IFT20; CCDC36; PCDH10

    Hayashi, M; Inoue, S; et al. Immunohistochemical Detection of Blue Light-Induced Phosphorylation of the Plasma Membrane H+-ATPase in Stomatal Guard Cells. PLANT AND CELL PHYSIOLOGY 52:1238-1248(2011).
    Yoshida, R; Hobo, T; et al. ABA-activated SnRK2 protein kinase is required for dehydration stress signaling in Arabidopsis. PLANT AND CELL PHYSIOLOGY 43:1473-1483(2002).

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