ABI2

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ABI2

Official Full Name abl-interactor 2
Background Abl interactor 2 also known as Abelson interactor 2 (Abi-2) is a protein that in humans is encoded by the ABI2 gene.
Synonyms ABI2; abl-interactor 2; abl interactor 2; ABI 2; ABI2B; AblBP3; AIP 1; argBPIA; SSH3BP2; Abelson interactor 2; Abl binding protein 3; Abl interacting protein 1 (SH3 containing protein); Abl interactor protein 2b; Arg binding protein 1; Arg protein tyrosine kinase binding protein; ArgBP1; ArgBPIB; OTTHUMP00000163783; OTTHUMP00000163784; OTTHUMP00000206182; OTTHUMP00000206183; OTTHUMP00000206184; OTTHUMP00000206185; abl-binding protein 3; arg-binding protein 1; abl-interactor protein 2b; arg protein tyrosine kinase-binding protein; abl-interacting protein 1 (SH3-containing protein); ABI-2; AIP-1
    • Species :
    • Human
    • Mouse
    • Source :
    • E.coli
    • E.Coli or Yeast
    • HEK293
    • HEK293T
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • Myc/DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human ABI2-087H Recombinant Human ABI2 Protein, GST-Tagged Wheat Germ GST
    Human ABI2-4266H Recombinant Human ABI2 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
    Human ABI2-9127HCL Recombinant Human ABI2 293 Cell Lysate HEK293 N/A
    Human ABI2-9247H Recombinant Human ABI2, GST-tagged E.coli GST
    Mouse ABI2-1138M Recombinant Mouse ABI2 Protein Mammalian Cell His
    Mouse Abi2-1475M Recombinant Mouse Abi2 Protein, Myc/DDK-tagged HEK293T Myc/DDK
    Mouse Abi2-3041M Recombinant Mouse Abi2, His-tagged E.Coli or Yeast His

    ABI2 involved in several pathways and played different roles in them. We selected most pathways ABI2 participated on our site, such as Fcgamma receptor (FCGR) dependent phagocytosis, Immune System, Innate Immune System, which may be useful for your reference. Also, other proteins which involved in the same pathway with ABI2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Fcgamma receptor (FCGR) dependent phagocytosis WASF2; NCKAP1; WASF3; ABI1; DOCK1; PLD4; WIPF2; ARPC1A; MYO1C; PPAPDC1A
    Immune System IRF6; SIGLEC9; UFL1; GBP6; TRAF7; UBE2F; NCKAP1; DYNC1H1; PRLRB; MKRN1
    Innate Immune System CRP; CLEC4D; NLRP3; DDX41; NLRP4C; DEFA3; CFHL3; S100A12; LY86; ACTR2B
    RAC1 signaling pathway NCKAP1; IQGAP3; NOXO1; ABI2; RACGAP1; BAIAP2; ABI1; NOXA1
    RHO GTPase Effectors EVL; NDEL1B; RCC2; TAX1BP3; KIF14; RANGAP1B; NCKIPSD; IQGAP3; SPC24; NUF2
    RHO GTPases Activate WASPs and WAVEs WIPF3; WASF3; NCKIPSD; WIPF2; ABI1A; ABI1B; ABI2
    Regulation of Actin Cytoskeleton MAP2K2; Itgam&Itgb2; RAF1A; FN1A; CD14; DIAPH3; PIK3R3B; MYL9B; FGF12A; FGF18A

    ABI2 has several biochemical functions, for example, DNA binding, contributes_to Rac GTPase binding, SH3 domain binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ABI2 itself. We selected most functions ABI2 had, and list some proteins which have the same functions with ABI2. You can find most of the proteins on our site.

    Function Related Protein
    DNA binding C3orf37; ZNF146; HIST1H2B7; NR6A1B; TBPL2; HMGA1B; HOXD13A; HOXB1B; ZNF3; RFXAP
    contributes_to Rac GTPase binding WASF1; CYFIP1; ABI2; NCKAP1; BRK1
    SH3 domain binding ARHGAP27; VASP; EFS; PTTG2; SH3BP5LA; SH3BP5B; CABYR; DNAJC6; SOS1; CTTNBP2
    cytoskeletal adaptor activity GAS2L2; GAS2L1; BAIAP2; NCK2; SDCBP; BAIAP2L2B; NCK1; ANK1; BICD1; BIN3
    kinase binding WWC3; JAKMIP2; LDHA; TRADD; WWC1; MOB4; GFAP; TNFAIP3; PRKCD; PFKM
    proline-rich region binding PFN1; TCERG1; CYLD; FAM59A; RABAC1; CSK; WBP4; YAP1; GAREM; BAIAP2L1
    protein binding TMEM41A; RRAGB; PRKD1; COG2; SRSF7; ATP6V1C2; MAZ; HDAC1; C1QA; ZNF10
    protein complex binding KRT8; NCKAP1; PGAM5; KAT6B; TUB; NCKAP1L; LRP2; BCAP31; NFKBIA; CRHR1
    ubiquitin protein ligase binding WASH1; UBE2L3; TRIM28; NAE1; TSG101; TRIB2; GPI; DNM1L; CD40; DBT

    ABI2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ABI2 here. Most of them are supplied by our site. Hope this information will be useful for your research of ABI2.

    NCK2; KRT15; IFT20; CCDC36; PCDH10

    Hayashi, M; Inoue, S; et al. Immunohistochemical Detection of Blue Light-Induced Phosphorylation of the Plasma Membrane H+-ATPase in Stomatal Guard Cells. PLANT AND CELL PHYSIOLOGY 52:1238-1248(2011).
    Yoshida, R; Hobo, T; et al. ABA-activated SnRK2 protein kinase is required for dehydration stress signaling in Arabidopsis. PLANT AND CELL PHYSIOLOGY 43:1473-1483(2002).

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