ABI2

  • Official Full Name

    abl-interactor 2

  • Overview

    Abl interactor 2 also known as Abelson interactor 2 (Abi-2) is a protein that in humans is encoded by the ABI2 gene.

  • Synonyms

    ABI2;abl-interactor 2;abl interactor 2;ABI 2;ABI2B;AblBP3;AIP 1;argBPIA;SSH3BP2;Abelson interactor 2;Abl binding protein 3;Abl interacting protein 1 (SH3 containing protein);Abl interactor protein 2b;Arg binding protein 1;Arg protein tyrosine kinase binding protein;ArgBP1;ArgBPIB;OTTHUMP00000163783;OTTHUMP00000163784;OTTHUMP00000206182;OTTHUMP00000206183;OTTHUMP00000206184;OTTHUMP00000206185;abl-binding protein 3;arg-binding protein 1;abl-interactor protein 2b;arg protein tyrosine kinase-binding protein;abl-interacting protein 1 (SH3-containing protein);ABI-2;AIP-1

Recombinant Proteins

  • Human
  • Mouse
  • E.coli
  • Mammalian Cells
  • E.Coli/Yeast
  • HEK293
  • In Vitro Cell Free System
  • GST
  • His
  • Non
  • DDK
  • Myc
  • Avi
  • Fc
Cat.# Product name Source (Host) Species Tag Protein Length Price
ABI2-9247H Recombinant Human ABI2 protein, GST-tagged E.coli Human GST 1-275 aa
SPP1-7901D Recombinant Dog SPP1 protein, His-tagged E.coli Human His Ile7~Ser232
ABI2-1138M Recombinant Mouse ABI2 Protein Mammalian Cells Mouse His
Abi2-3041M Recombinant Mouse Abi2, His-tagged E.Coli/Yeast Mouse His 487
ABI2-9127HCL Recombinant Human ABI2 293 Cell Lysate HEK293 Human Non
Abi2-1475M Recombinant Mouse Abi2 Protein, Myc/DDK-tagged HEK293 Mouse DDK&Myc
ABI2-220M Recombinant Mouse ABI2 Protein, His (Fc)-Avi-tagged HEK293 Mouse Avi&Fc&His
ABI2-220M-B Recombinant Mouse ABI2 Protein Pre-coupled Magnetic Beads HEK293 Mouse
ABI2-3532H Recombinant Human ABI2 protein, His-tagged E.coli Human His 1-275 aa
ABI2-4266H Recombinant Human ABI2 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293 Human DDK&Myc
ABI2-891HF Recombinant Full Length Human ABI2 Protein, GST-tagged In Vitro Cell Free System Human GST Full L. 475 amino acids

    Involved Pathway

    ABI2 involved in several pathways and played different roles in them. We selected most pathways ABI2 participated on our site, such as Fcgamma receptor (FCGR) dependent phagocytosis,Immune System,Innate Immune System, which may be useful for your reference. Also, other proteins which involved in the same pathway with ABI2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Innate Immune System POLR3H,TLR10,TREX1,CD300LB,PANX1,TRIM56,SIGLEC15,IFI16,TXNIPB,NLRP4B
    RHO GTPases Activate WASPs and WAVEs ABI1A,WASF3,WIPF2,NCKIPSD,ABI1B,WIPF3
    Fcgamma receptor (FCGR) dependent phagocytosis WASF2,ACTR2,IgG3,ACTR2B,WASF3,ABI1,ABI1B,DOCK1,WIPF2,ABI1A
    RHO GTPase Effectors NF2A,RHOC,CDCA8,BAIAP2,ZWILCH,SPDL1,ABI1A,ZWINT,KNTC1,KTN1
    Immune System DEFB129,CFHL1,DZIP3,XAF1,MGC174152,TRIM9,CFHL3,SLAMF6,CTSC,DEFB125
    Regulation of actin cytoskeleton BRAF,RASSF7,FGF16,EGFRA,CDC42,ARAF,PDGFRB,FGFR4,PIK3R5,MRAS
    RAC1 signaling pathway ABI1,NCKAP1,RACGAP1,NOXO1,IQGAP3,NOXA1,BAIAP2

    Protein Function

    ABI2 has several biochemical functions, for example, DNA binding,contributes_to Rac GTPase binding,SH3 domain binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ABI2 itself. We selected most functions ABI2 had, and list some proteins which have the same functions with ABI2. You can find most of the proteins on our site.

    Function Related Protein
    proline-rich region binding WBP4,APBB1,ABL1,FAM59A,ITSN1,YAP1,PFN1,NEDD4,BAIAP2,GAREM
    SH3 domain binding CRB3,DENND1A,EVL,ILK,INPP5D,DOCK4,ELMO3,PARK2,QKI,CD3E
    protein complex binding PCSK2,TG,GNB1,KAT2B,PRKACA,ST13,Ctsl,LZTFL1,ATP6V0D1,LCA5
    DNA binding ZFP93,KCNH7,PPARAB,ASH1L,HNRPDL,SP9,CCDC79,LIN54,PMS2,ZNF157
    protein binding NSUN4,TBX1,RRS1,AMFR,COBL,MTAP1A,SETD2,ANKHD1,RALGAPA1,GNE
    ubiquitin protein ligase binding CUL1A,NPLOC4,UBE2R2,PRKACA,BRCA1,CXCR4,RNF34,HSPD1,TRIM28,MAGEC2
    kinase binding SIT1,CAB39,UBQLN1,RB1,JAKMIP3,PPP2R5A,FAS,HAP1,WWC2,MOB4
    cytoskeletal adaptor activity BAIAP2L1,BIN3,NCK2,COX4I2,BAIAP2L2,BAIAP2L1A,NCK1,BICD1,SDCBP,BAIAP2
    contributes_to Rac GTPase binding NCKAP1,BRK1,WASF1,CYFIP1

    Interacting Protein

    ABI2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ABI2 here. Most of them are supplied by our site. Hope this information will be useful for your research of ABI2.

    NCK2;KRT15;IFT20;CCDC36;PCDH10

    Resources

    References

    • Hayashi, M; Inoue, S; et al. Immunohistochemical Detection of Blue Light-Induced Phosphorylation of the Plasma Membrane H+-ATPase in Stomatal Guard Cells. PLANT AND CELL PHYSIOLOGY 52:1238-1248(2011).
    • Yoshida, R; Hobo, T; et al. ABA-activated SnRK2 protein kinase is required for dehydration stress signaling in Arabidopsis. PLANT AND CELL PHYSIOLOGY 43:1473-1483(2002).

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