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Official Full Name alkaline ceramidase 2
Background The sphingolipid metabolite sphingosine-1-phosphate promotes cell proliferation and survival, whereas its precursor,;sphingosine, has the opposite effect. The ceramidase ACER2 hydrolyzes very long chain ceramides to generate;sphingosine (Xu et al., 2006 (PubMed 16940153)).
Synonyms ACER2; alkaline ceramidase 2; ASAH3L, N acylsphingosine amidohydrolase 3 like; FLJ41587; haCER2; alkCDase 2; alkaline CDase 2; ceramide hydrolase; ASAH3L; ALKCDase2
    • Species :
    • Human
    • Source :
    • Wheat Germ
    • Tag :
    • GST
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human ASAH3L-879H Recombinant Human ASAH3L protein, GST-tagged Wheat Germ GST

    acer2 involved in several pathways and played different roles in them. We selected most pathways acer2 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with acer2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein

    acer2 has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by acer2 itself. We selected most functions acer2 had, and list some proteins which have the same functions with acer2. You can find most of the proteins on our site.

    Function Related Protein

    acer2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with acer2 here. Most of them are supplied by our site. Hope this information will be useful for your research of acer2.

    Sasaki, H; Toyomura, K; et al. Regulation of alkaline ceramidase activity by the c-Src-mediated pathway. ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 550:12-19(2014).
    Snider, AJ; Wu, BX; et al. Loss of neutral ceramidase increases inflammation in a mouse model of inflammatory bowel disease. PROSTAGLANDINS & OTHER LIPID MEDIATORS 99:124-130(2012).

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