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Official Full Name ADAM metallopeptidase with thrombospondin type 1 motif, 10
Background This gene belongs to the ADAMTS (a disintegrin and metalloproteinase domain with thrombospondin type-1 motifs) family of zinc-dependent proteases. ADAMTS proteases are complex secreted enzymes containing a prometalloprotease domain of the reprolysin type attached to an ancillary domain with a highly conserved structure that includes at least one thrombospondin type 1 repeat. They have been demonstrated to have important roles in connective tissue organization, coagulation, inflammation, arthritis, angiogenesis and cell migration. The product of this gene plays a major role in growth and in skin, lens, and heart development. It is also a candidate gene for autosomal recessive Weill-Marchesani syndrome. [provided by RefSeq, Jul 2008]
Synonyms ADAMTS10; ADAM metallopeptidase with thrombospondin type 1 motif, 10; WMS; WMS1; ADAM-TS10; ADAMTS-10; A disintegrin and metalloproteinase with thrombospondin motifs 10; ADAM-TS 10; zinc metalloendopeptidase; a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 10;
    • Species :
    • Human
    • Mouse
    • Rhesus Macaque
    • Zebrafish
    • Source :
    • E.coli
    • E.Coli or Yeast
    • HEK293
    • Mammalian Cell
    • Tag :
    • His
    • T7
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human ADAMTS10-1759H Recombinant Human ADAMTS10 protein, His & T7-tagged E.coli His/T7
    Human ADAMTS10-297H Recombinant Human ADAMTS10 Protein E.coli N/A
    Human ADAMTS10-9032HCL Recombinant Human ADAMTS10 293 Cell Lysate HEK293 N/A
    Mouse ADAMTS10-1308M Recombinant Mouse ADAMTS10 Protein Mammalian Cell His
    Mouse Adamts10-3010M Recombinant Mouse Adamts10, His-tagged E.Coli or Yeast His
    Rhesus Macaque ADAMTS10-235R Recombinant Rhesus monkey ADAMTS10 Protein, His-tagged Mammalian Cell His
    Zebrafish ADAMTS10-6664Z Recombinant Zebrafish ADAMTS10 Mammalian Cell His

    ADAMTS10 involved in several pathways and played different roles in them. We selected most pathways ADAMTS10 participated on our site, such as Metabolism of proteins, O-glycosylation of TSR domain-containing proteins, O-linked glycosylation, which may be useful for your reference. Also, other proteins which involved in the same pathway with ADAMTS10 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Metabolism of proteins DHPS; IGFBP5; ADAMTS20; PREB; UBA2; FBXW9; NAPG; MUCL1; EXOC8; ST6GALNAC1.2
    O-glycosylation of TSR domain-containing proteins SPON1A; C8orf84; SSPO; ADAMTS5; B3GALTL; THSD7A; ADAMTS3; ADAMTSL3; ADAMTS4; ADAMTS18
    O-linked glycosylation SPON1B; A4GNT; B3GALTL; SPON1A; ADAMTSL1; THSD7A; GALNT6; SSPO; ADAMTS8; B3GNT6
    Post-translational protein modification TRAPPC3; TMED2; MCFD2; SENP5; TMED10; SENP1; SPON1; NEU3; EIF5A; CNIH2

    ADAMTS10 has several biochemical functions, for example, metalloendopeptidase activity, molecular_function, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ADAMTS10 itself. We selected most functions ADAMTS10 had, and list some proteins which have the same functions with ADAMTS10. You can find most of the proteins on our site.

    Function Related Protein
    metalloendopeptidase activity UQCRC2A; UQCRC2; KEL; PAPPAB; MIPEP; BMP1A; MMP14A; OMA1; ECEL1; MMP8
    molecular_function DET1; VPS45; SPRR2A2; SERF1B; CTAG2; FAM154B; FAM198A; LMAN1L; TMEM235; ATXN7L3B
    protein binding C2orf63; MAB21L1; UVRAG; BCAS2; NMRK1; ROCK2A; TAF6L; AP2S1; USP5; JUP
    zinc ion binding FHL1A; ZDHHC15A; USP20; NPEPPS; QPCTLA; MMP30; RNF148; UBR3; ING1; SETMAR

    ADAMTS10 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ADAMTS10 here. Most of them are supplied by our site. Hope this information will be useful for your research of ADAMTS10.


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