ADAMTS10
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Official Full Name
ADAM metallopeptidase with thrombospondin type 1 motif, 10
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Overview
This gene belongs to the ADAMTS (a disintegrin and metalloproteinase domain with thrombospondin type-1 motifs) family of zinc-dependent proteases. ADAMTS proteases are complex secreted enzymes containing a prometalloprotease domain of the reprolysin type attached to an ancillary domain with a highly conserved structure that includes at least one thrombospondin type 1 repeat. They have been demonstrated to have important roles in connective tissue organization, coagulation, inflammation, arthritis, angiogenesis and cell migration. The product of this gene plays a major role in growth and in skin, lens, and heart development. It is also a candidate gene for autosomal recessive Weill-Marchesani syndrome. [provided by RefSeq, Jul 2008] -
Synonyms
ADAMTS10; ADAM metallopeptidase with thrombospondin type 1 motif, 10; WMS; WMS1; ADAM-TS10; ADAMTS-10; A disintegrin and metalloproteinase with thrombospondin motifs 10; ADAM-TS 10; zinc metalloendopeptidase; a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 10;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Human
- Mouse
- Rhesus Macaque
- Zebrafish
- E.coli
- E.Coli or Yeast
- HEK293
- Mammalian Cell
- His
- His (Fc)
- Avi
- His|T7
- N/A
| Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| Human | ADAMTS10-297H | Recombinant Human ADAMTS10 Protein | E.coli | N/A |
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| Human | ADAMTS10-9032HCL | Recombinant Human ADAMTS10 293 Cell Lysate | HEK293 | N/A |
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| Human | ADAMTS10-1759H | Recombinant Human ADAMTS10 protein, His & T7-tagged | E.coli | His/T7 | Arg239~Pro602 (Accession # Q9H324) |
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| Mouse | ADAMTS10-1308M | Recombinant Mouse ADAMTS10 Protein | Mammalian Cell | His |
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| Mouse | Adamts10-3010M | Recombinant Mouse Adamts10, His-tagged | E.Coli or Yeast | His | 1104 |
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| Mouse | ADAMTS10-322M | Recombinant Mouse ADAMTS10 Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi |
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| Mouse | ADAMTS10-322M-B | Recombinant Mouse ADAMTS10 Protein Pre-coupled Magnetic Beads | HEK293 |
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| Rhesus Macaque | ADAMTS10-235R | Recombinant Rhesus monkey ADAMTS10 Protein, His-tagged | Mammalian Cell | His |
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| Rhesus Macaque | ADAMTS10-63R-B | Recombinant Rhesus Macaque ADAMTS10 Protein Pre-coupled Magnetic Beads | HEK293 |
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| Rhesus Macaque | ADAMTS10-63R | Recombinant Rhesus Macaque ADAMTS10 Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi |
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| Zebrafish | ADAMTS10-6664Z | Recombinant Zebrafish ADAMTS10 | Mammalian Cell | His |
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- Involved Pathway
- Protein Function
- Interacting Protein
- ADAMTS10 Related Research Area
ADAMTS10 involved in several pathways and played different roles in them. We selected most pathways ADAMTS10 participated on our site, such as Metabolism of proteins, O-glycosylation of TSR domain-containing proteins, O-linked glycosylation, which may be useful for your reference. Also, other proteins which involved in the same pathway with ADAMTS10 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Metabolism of proteins | GPR116;FBXW9;IGFBP6A;GPR120;KCNA3;ZDHHC2;MUC15;LMAN2;ODAM |
| O-glycosylation of TSR domain-containing proteins | ADAMTSL3;SPON1A;ADAMTS4;ADAMTS5;ADAMTS1;ADAMTS15;THSD1;C8orf84;THSD7A |
| O-linked glycosylation | GCNT3;SPON1;ADAMTS10;ADAMTS3;SSPO;ADAMTS18;MUC12;GALNT13;ADAMTS8 |
| Post-translational protein modification | ANKRD28;TRAPPC1;RING1;ADAMTS8;TRAPPC10;MPDU1A;THSD7A;MUC21;SEC16B |
ADAMTS10 has several biochemical functions, for example, metalloendopeptidase activity, molecular_function, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ADAMTS10 itself. We selected most functions ADAMTS10 had, and list some proteins which have the same functions with ADAMTS10. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| metalloendopeptidase activity | MMP24;MMP9;ADAMTSL5;ADAM2;AFG3L2;IDE;ADAMTS9;ADAM17A;Adam6 |
| molecular_function | RAD21L1;LMAN2LB;GLIPR1B;NOG1;GPR62;NXPE4;NOL4LB;ASB16;EMC6 |
| protein binding | HIST1H2AL;PTPRR;TNFRSF1B;GPR37L1;C19orf47;ARHGAP17;KIAA1530;SEMG1;USP10 |
| zinc ion binding | RARAB;ADAM28;BRF1;RNF114;PEX10;PNMA3;XIRP2;ADH7;RNF139 |
ADAMTS10 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ADAMTS10 here. Most of them are supplied by our site. Hope this information will be useful for your research of ADAMTS10.
TK1; ANXA7; HMGCL; CDKN1A; SMN1; PCYT2; LAMTOR3
- Q&As
- Reviews
Q&As (10)
Ask a questionADAMTS10 is mainly involved in the study ofpancreatic cancer, breast cancer and lung cancer.
Yes, they interact with each other and are co-located in human skin.
Yes, we can ship according to the product form you specify.
ADAMTS10 is mainly expressed in the lung, kidney and bone.
Yes, this promotion applies to all protein products and custom needs.
Human ADAMTS10 protein is in stock.
ADAM10 cleaves transmembrane proteins such as amyloid precursor protein, E-calmodulin, N-calmodulin and NOTCH.
We can customize the tag according to your requirements.
High expression of ADAM10 leads to Notch signal pathway activation and stimulation of VSMCs proliferation.
We provide several different protein expression systems, including baculovirus-insect cell expression systems, cell-free in vitro protein expression systems, yeast expression systems, etc.
Customer Reviews (3)
Write a reviewPrompt dispatch and smooth delivery helped me to obtain satisfactory experimental results within a short period of time
The ADAMTS10 protein purchased was suitable for WB experiments and the experiments went very well and satisfactory results were obtained
The delivery is very fast, the protein activity is good, and it can show good experimental results.
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