Recombinant Human ADAMTS10 Protein

• Cat.No.: ADAMTS10-297H
• Product Overview: Human ADAMTS10 (NP_001101.1, 214 a.a. - 672 a.a.) partial recombinant protein expressed in Escherichia coli.

Specification

• Description: This gene belongs to the ADAMTS (a disintegrin and metalloproteinase domain with thrombospondin type-1 motifs) family of zinc-dependent proteases. ADAMTS proteases are complex secreted enzymes containing a prometalloprotease domain of the reprolysin type attached to an ancillary domain with a highly conserved structure that includes at least one thrombospondin type 1 repeat. They have been demonstrated to have important roles in connective tissue organization, coagulation, inflammation, arthritis, angiogenesis and cell migration. The product of this gene plays a major role in growth and in skin, lens, and heart development. It is also a candidate gene for autosomal recessive Weill-Marchesani syndrome. [provided by RefSeq, Jul 2008]
• Source: E. coli
• Species: Human
• Form: Liquid
• AA Sequence: TTSAEKNTCQLYIQTDHLFFKYYGT REAVIAQISSHVKAIDTIYQTTDFS GIRNISFMVKRIRINTTADEKDPTN PFRFPNIGVEKFLELNSEQNHDDYC LAYVFTDRDFDDGVLGLAWVGAPSG SSGGICEKSKLYSDGKKKSLNTGII TVQNYGSHVPPKVSHITFAHEVGHN FGSPHDSGTECTPGESKNLGQKENG NYIMYARATSGDKLNNNKFSLCSIR NISQVLEKKRNNCFVESGQPICGNG MVEQGEECDCGYSDQCKDECCFDAN QPEGRKCKLKPGKQCSPSQGPCCTA QCAFKSKSEKCRDDSDCAREGICNG FTALCPASDPKPNFTDCNRHTQVCI NGQCAGSICEKYGLEECTCASSDGK DDKELCHVCCMKKMDPSTCASTGSV QWSRHFSGRTITLQPGSPCNDFRGY CDVFMRCRLVDADGPLARLKKAIFS PELYENIAE
• Purity: > 95% by SDS-PAGE
• Applications: SDS-PAGE
• Storage: Store at -20 centigrade. For long term storage store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: In PBS (50% glycerol)

Gene Information

• Gene Name: ADAMTS10 ADAM metallopeptidase with thrombospondin type 1 motif, 10 [ Homo sapiens ]
• Official Symbol: ADAMTS10
• Synonyms: ADAMTS10; ADAM metallopeptidase with thrombospondin type 1 motif, 10; a disintegrin like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 10; A disintegrin and metalloproteinase with thrombospondin motifs 10; ADAM TS10; ADAMTS-10; ADAM-TS 10; zinc metalloendopeptidase; a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 10; WMS; WMS1; ADAM-TS10
• Gene ID: 81794
• mRNA Refseq: NM_030957
• Protein Refseq: NP_112219
• MIM: 608990
• UniProt ID: Q9H324