Recombinant Human ADAMTS10 protein, His & T7-tagged

• Cat.No.: ADAMTS10-1759H
• Product Overview: Recombinant Human ADAMTS10 aa. (Arg239~Pro602 (Accession # Q9H324)) fused with N-terminal His & T7 tag was produced in E. coli cells.

Specification

• Description: This gene belongs to the ADAMTS (a disintegrin and metalloproteinase domain with thrombospondin type-1 motifs) family of zinc-dependent proteases. ADAMTS proteases are complex secreted enzymes containing a prometalloprotease domain of the reprolysin type attached to an ancillary domain with a highly conserved structure that includes at least one thrombospondin type 1 repeat. They have been demonstrated to have important roles in connective tissue organization, coagulation, inflammation, arthritis, angiogenesis and cell migration. The product of this gene plays a major role in growth and in skin, lens, and heart development. It is also a candidate gene for autosomal recessive Weill-Marchesani syndrome.
• Source: E. coli
• Species: Human
• Tag: His & T7
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 43.7kDa
• Protein length: Arg239~Pro602 (Accession # Q9H324)
• Endotoxin: <1.0EU per 1ug (determined by the LAL method)
• Purity: >95%
• Applications: SDS-PAGE; WB; ELISA; IP.
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
• Storage buffer: Supplied as lyophilized form in PBS, pH7.4, containing 5% trehalose, 0.01% sarcosyl.
• Reconstitution: Reconstitute in sterile PBS, pH7.2-pH7.4.
• Isoelectric Point: 7.8

Gene Information

• Gene Name: ADAMTS10 ADAM metallopeptidase with thrombospondin type 1 motif 10 [ Homo sapiens (human) ]
• Official Symbol: ADAMTS10
• Synonyms: ADAMTS10; ADAM metallopeptidase with thrombospondin type 1 motif 10; WMS; WMS1; ADAM-TS10; ADAMTS-10; A disintegrin and metalloproteinase with thrombospondin motifs 10; ADAM-TS 10; a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 10; zinc metalloendopeptidase
• Gene ID: 81794
• mRNA Refseq: NM_001282352.1
• Protein Refseq: NP_001269281.1
• UniProt ID: Q9H324