ADRB1 Protein

ADRB1

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ADRB1

Official Full Name adrenergic, beta-1-, receptor
Background The adrenergic receptors (subtypes alpha 1, alpha 2, beta 1, and beta 2) are a prototypic family of guanine nucleotide binding regulatory protein-coupled receptors that mediate the physiological effects of the hormone epinephrine and the neurotransmitter norepinephrine. Specific polymorphisms in this gene have been shown to affect the resting heart rate and can be involved in heart failure.
Synonyms ADRB1; adrenergic, beta-1-, receptor; beta-1 adrenergic receptor; ADR B1; ADRB 1; ADRB1_HUMAN; ADRB1R; Adrenergic beta 1 receptor; B1AR; Beta 1 adrenoceptor; Beta 1 adrenoreceptor; Beta-1 adrenoceptor; Beta-1 adrenoreceptor; BETA1AR; RHR
    • Species :
    • Bos taurus (Bovine)
    • Canis lupus familiaris (Dog) (Canis familiaris)
    • Felis catus (Cat) (Felis silvestris catus)
    • Homo sapiens (Human)
    • Human
    • Macaca mulatta (Rhesus macaque)
    • Meleagris gallopavo (Wild turkey)
    • Meriones unguiculatus (Mongolian jird) (Mongolian gerbil)
    • Mouse
    • Mus musculus (Mouse)
    • Ovis aries (Sheep)
    • Rat
    • Rattus norvegicus (Rat)
    • Rhesus Macaque
    • Sus scrofa (Pig)
    • Xenopus laevis (African clawed frog)
    • Zebrafish
    • Source :
    • E.coli
    • E.coli expression system
    • HEK293
    • Insect Cell
    • Mammalian Cell
    • Sf9 Insect Cell
    • Yeast
    • Tag :
    • Flag
    • His
    • His&Flag
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human ADRB1-1017H Active Recombinant Human Adrenergic, Beta-1-, Receptor, Flag-His Sf9 Insect Cell Flag/His Inquiry
    Human ADRB1-1035H Recombinant Human ADBR1 and GsαS fusion protein, Flag and His-tagged Insect Cell N/A Inquiry
    Mouse ADRB1-1385M Recombinant Mouse ADRB1 Protein Mammalian Cell His Inquiry
    Rat ADRB1-544R Recombinant Rat ADRB1 Protein Mammalian Cell His Inquiry
    Rhesus Macaque ADRB1-259R Recombinant Rhesus monkey ADRB1 Protein, His-tagged Mammalian Cell His Inquiry
    Zebrafish ADRB1-6980Z Recombinant Zebrafish ADRB1 Mammalian Cell His Inquiry
    Human ADRB1-1130HFL Recombinant Human ADRB1 protein, His&Flag-tagged HEK293 His&Flag Inquiry
    Human ADRB1-5987H Recombinant Human ADRB1 protein, His-tagged E.coli His Inquiry
    Rattus norvegicus (Rat) RFL-12399RF Recombinant Full Length Rat Beta-1 Adrenergic Receptor(Adrb1) Protein, His-Tagged E.coli expression system His Inquiry
    Meriones unguiculatus (Mongolian jird) (Mongolian gerbil) RFL-1503MF Recombinant Full Length Meriones Unguiculatus Beta-1 Adrenergic Receptor(Adrb1) Protein, His-Tagged E.coli expression system His Inquiry
    Canis lupus familiaris (Dog) (Canis familiaris) RFL-24265CF Recombinant Full Length Dog Beta-1 Adrenergic Receptor(Adrb1) Protein, His-Tagged E.coli expression system His Inquiry
    Sus scrofa (Pig) RFL28316SF Recombinant Full Length Pig Beta-1 Adrenergic Receptor(Adrb1) Protein, His-Tagged E.coli expression system His Inquiry
    Mus musculus (Mouse) RFL-35791MF Recombinant Full Length Mouse Beta-1 Adrenergic Receptor(Adrb1) Protein, His-Tagged E.coli expression system His Inquiry
    Homo sapiens (Human) RFL-36213HF Recombinant Full Length Human Beta-1 Adrenergic Receptor(Adrb1) Protein, His-Tagged E.coli expression system His Inquiry
    Bos taurus (Bovine) RFL36974BF Recombinant Full Length Bovine Beta-1 Adrenergic Receptor(Adrb1) Protein, His-Tagged E.coli expression system His Inquiry
    Ovis aries (Sheep) RFL5668OF Recombinant Full Length Sheep Beta-1 Adrenergic Receptor(Adrb1) Protein, His-Tagged E.coli expression system His Inquiry
    Xenopus laevis (African clawed frog) RFL-6947XF Recombinant Full Length Xenopus Laevis Beta-1 Adrenergic Receptor(Adrb1) Protein, His-Tagged E.coli expression system His Inquiry
    Felis catus (Cat) (Felis silvestris catus) RFL7354FF Recombinant Full Length Cat Beta-1 Adrenergic Receptor(Adrb1) Protein, His-Tagged E.coli expression system His Inquiry
    Meleagris gallopavo (Wild turkey) RFL-9087MF Recombinant Full Length Meleagris Gallopavo Beta-1 Adrenergic Receptor(Adrb1) Protein, His-Tagged E.coli expression system His Inquiry
    Macaca mulatta (Rhesus macaque) RFL-9732MF Recombinant Full Length Macaca Mulatta (Rhesus Macaque) Beta-1 Adrenergic Receptor(Adrb1) Protein, His-Tagged E.coli expression system His Inquiry
    Human ADRB1-01H Recombinant Human ADRB1 Protein, His-tagged Yeast His Inquiry
    Human ADRB1-1319H Recombinant Human ADRB1 Protein (378-477 aa), His-tagged Yeast His Inquiry
    Kit-0966 TR-FRET LXR beta Coactivator Assay Kit, goat N/A Inquiry
    Kit-1082 Phospholipase A2 Activity Assay Kit (Fluorometric) N/A Inquiry
    Kit-1112 Protein Synthesis Monitoring Assay Kit (Flow Cytometry) N/A Inquiry
    Kit-1113 Cystathionine β Synthase Activity Assay Kit (Fluorometric) N/A Inquiry
    Kit-2183 cAMP ADRB1 CHO-K1 GPCR Assay Kit N/A Inquiry
    Kit-2184 ADRB1 CHO-K1 β-Arrestin GPCR Assay Kit N/A Inquiry

    ADRB1 involved in several pathways and played different roles in them. We selected most pathways ADRB1 participated on our site, such as Adrenergic signaling in cardiomyocytes, Adrenoceptors, Amine ligand-binding receptors, which may be useful for your reference. Also, other proteins which involved in the same pathway with ADRB1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Adrenergic signaling in cardiomyocytes ATP2B4; CAMK2B1; PPP2R5C; CALM3; ATF4B1; AGTR1A; VMHCL; ADRB2; TNNT2; CREB5
    Adrenoceptors ADRB2; ADRa1A; ADRA2B; ADRA2A; ADRA1D; ADRA1B; ADRB1; ADRB3; ADRA2C
    Amine ligand-binding receptors ADRB1; DRD1; CHRM2; ADRA1B; ADRA2A; TAAR1; ADRA1D; DRD2; DRD3; CHRM4
    Calcium Regulation in the Cardiac Cell GJB3; RGS4; KCNJ5; CX27.5; GJA10; GNB3B; GJB1; CHRM2; ADRa1A; CASQ2
    Calcium signaling pathway PPIFA; CALM2; ATP2A1; CACNA1H; GNAL; HTR5AL; ADORA2A; CHRM5; PTAFR; ORAI3
    Class A/1 (Rhodopsin-like receptors) SST1.1; GPR39; UTS2D; GRP; ADRB2; EDN1; CGA; CCR7; APLNR; SSTR2
    Dilated cardiomyopathy EMD; DMD; ADRB1; CACNG3; TNNC1; TGFB1; ITGA5; ITGB8; ITGA9; CACNG1
    Endocytosis EPN2; ARR3A; D6WSU116E; EEA1; ARPC5L; ARPC5LB; ARPC1B; KITB; RAB31; ARF1L

    ADRB1 has several biochemical functions, for example, PDZ domain binding, Ras guanyl-nucleotide exchange factor activity, alpha-2A adrenergic receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ADRB1 itself. We selected most functions ADRB1 had, and list some proteins which have the same functions with ADRB1. You can find most of the proteins on our site.

    Function Related Protein
    PDZ domain binding CADM1; ATP2B1; ADAM17; LPAR2; GRIA1; ACOX1; PLEKHA1; ATP2B4; ERC1; LNX1
    Ras guanyl-nucleotide exchange factor activity RASGEF1A; ADRB1; RASGRP4; SOS1; RAB3A; RASGEF1B; RASGEF1BB; RGL2; KNDC1; RAPGEF5
    alpha-2A adrenergic receptor binding ADRA2C; APLP1; ADRBK1; ADRB1; UCHL1
    beta-adrenergic receptor activity ADRB3; ADRB1
    beta1-adrenergic receptor activity ADRB1
    epinephrine binding ADRA2B; ADRB3; ADRB2B; ADRA2C; ADRB3A; ADRB3B; ADRA2A; ADRB2; ADRB1; ADRB2A
    norepinephrine binding ADRB3A; ADRB1; ADRA2A; ADRB2; ADRB3B
    protein binding HBA2; UTP23; CALCOCO1; LLGL1; NKX2-5; MAP2K7; TEKT1; BEX5; GTSE1; SULT2A1
    protein heterodimerization activity POLE3; HIST1H2BB; HSPD1; CEBPG; TAL1; PRMT5; HEXB; MYF5; GUCY1A3; CD3E
    receptor signaling protein activity RAF1A; CD19; IL4R; FCGR1A; ARF1; RGS14; CD3E; DOK1; PLCG1; TGFBR1

    ADRB1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ADRB1 here. Most of them are supplied by our site. Hope this information will be useful for your research of ADRB1.

    MAGI2; MAGI3; Dlg4; GPRASP1; Dlg1; GPRASP2; MAGI1; GOPC; Gipc1; atenolol

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