Official Full Name | adrenergic, beta-1-, receptor |
Background | The adrenergic receptors (subtypes alpha 1, alpha 2, beta 1, and beta 2) are a prototypic family of guanine nucleotide binding regulatory protein-coupled receptors that mediate the physiological effects of the hormone epinephrine and the neurotransmitter norepinephrine. Specific polymorphisms in this gene have been shown to affect the resting heart rate and can be involved in heart failure. |
Synonyms | ADRB1; adrenergic, beta-1-, receptor; beta-1 adrenergic receptor; ADR B1; ADRB 1; ADRB1_HUMAN; ADRB1R; Adrenergic beta 1 receptor; B1AR; Beta 1 adrenoceptor; Beta 1 adrenoreceptor; Beta-1 adrenoceptor; Beta-1 adrenoreceptor; BETA1AR; RHR |
Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
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ADRB1 involved in several pathways and played different roles in them. We selected most pathways ADRB1 participated on our site, such as Adrenergic signaling in cardiomyocytes, Adrenoceptors, Amine ligand-binding receptors, which may be useful for your reference. Also, other proteins which involved in the same pathway with ADRB1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
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Adrenergic signaling in cardiomyocytes | ATP2B4; CAMK2B1; PPP2R5C; CALM3; ATF4B1; AGTR1A; VMHCL; ADRB2; TNNT2; CREB5 |
Adrenoceptors | ADRB2; ADRa1A; ADRA2B; ADRA2A; ADRA1D; ADRA1B; ADRB1; ADRB3; ADRA2C |
Amine ligand-binding receptors | ADRB1; DRD1; CHRM2; ADRA1B; ADRA2A; TAAR1; ADRA1D; DRD2; DRD3; CHRM4 |
Calcium Regulation in the Cardiac Cell | GJB3; RGS4; KCNJ5; CX27.5; GJA10; GNB3B; GJB1; CHRM2; ADRa1A; CASQ2 |
Calcium signaling pathway | PPIFA; CALM2; ATP2A1; CACNA1H; GNAL; HTR5AL; ADORA2A; CHRM5; PTAFR; ORAI3 |
Class A/1 (Rhodopsin-like receptors) | SST1.1; GPR39; UTS2D; GRP; ADRB2; EDN1; CGA; CCR7; APLNR; SSTR2 |
Dilated cardiomyopathy | EMD; DMD; ADRB1; CACNG3; TNNC1; TGFB1; ITGA5; ITGB8; ITGA9; CACNG1 |
Endocytosis | EPN2; ARR3A; D6WSU116E; EEA1; ARPC5L; ARPC5LB; ARPC1B; KITB; RAB31; ARF1L |
ADRB1 has several biochemical functions, for example, PDZ domain binding, Ras guanyl-nucleotide exchange factor activity, alpha-2A adrenergic receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ADRB1 itself. We selected most functions ADRB1 had, and list some proteins which have the same functions with ADRB1. You can find most of the proteins on our site.
Function | Related Protein |
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PDZ domain binding | CADM1; ATP2B1; ADAM17; LPAR2; GRIA1; ACOX1; PLEKHA1; ATP2B4; ERC1; LNX1 |
Ras guanyl-nucleotide exchange factor activity | RASGEF1A; ADRB1; RASGRP4; SOS1; RAB3A; RASGEF1B; RASGEF1BB; RGL2; KNDC1; RAPGEF5 |
alpha-2A adrenergic receptor binding | ADRA2C; APLP1; ADRBK1; ADRB1; UCHL1 |
beta-adrenergic receptor activity | ADRB3; ADRB1 |
beta1-adrenergic receptor activity | ADRB1 |
epinephrine binding | ADRA2B; ADRB3; ADRB2B; ADRA2C; ADRB3A; ADRB3B; ADRA2A; ADRB2; ADRB1; ADRB2A |
norepinephrine binding | ADRB3A; ADRB1; ADRA2A; ADRB2; ADRB3B |
protein binding | HBA2; UTP23; CALCOCO1; LLGL1; NKX2-5; MAP2K7; TEKT1; BEX5; GTSE1; SULT2A1 |
protein heterodimerization activity | POLE3; HIST1H2BB; HSPD1; CEBPG; TAL1; PRMT5; HEXB; MYF5; GUCY1A3; CD3E |
receptor signaling protein activity | RAF1A; CD19; IL4R; FCGR1A; ARF1; RGS14; CD3E; DOK1; PLCG1; TGFBR1 |
ADRB1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ADRB1 here. Most of them are supplied by our site. Hope this information will be useful for your research of ADRB1.
MAGI2; MAGI3; Dlg4; GPRASP1; Dlg1; GPRASP2; MAGI1; GOPC; Gipc1; atenolol
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