ADRB1

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ADRB1

Official Full Name adrenergic, beta-1-, receptor
Background The adrenergic receptors (subtypes alpha 1, alpha 2, beta 1, and beta 2) are a prototypic family of guanine nucleotide binding regulatory protein-coupled receptors that mediate the physiological effects of the hormone epinephrine and the neurotransmitter norepinephrine. Specific polymorphisms in this gene have been shown to affect the resting heart rate and can be involved in heart failure.
Synonyms ADRB1; adrenergic, beta-1-, receptor; beta-1 adrenergic receptor; ADR B1; ADRB 1; ADRB1_HUMAN; ADRB1R; Adrenergic beta 1 receptor; B1AR; Beta 1 adrenoceptor; Beta 1 adrenoreceptor; Beta-1 adrenoceptor; Beta-1 adrenoreceptor; BETA1AR; RHR
    • Species :
    • Human
    • Mouse
    • Rat
    • Rhesus Macaque
    • Zebrafish
    • Source :
    • Insect Cell
    • Mammalian Cell
    • Sf9 Insect Cell
    • Yeast
    • Tag :
    • Flag
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human ADRB1-01H Recombinant Human ADRB1 Protein, His-tagged Yeast His
    Human ADRB1-1017H Recombinant Human Adrenergic, Beta-1-, Receptor, Flag-His Sf9 Insect Cell Flag/His
    Human ADRB1-1035H Recombinant Human ADBR1 and GsαS fusion protein, Flag and His-tagged Insect Cell N/A
    Human ADRB1-1319H Recombinant Human ADRB1 Protein (378-477 aa), His-tagged Yeast His
    Mouse ADRB1-1385M Recombinant Mouse ADRB1 Protein Mammalian Cell His
    Rat ADRB1-544R Recombinant Rat ADRB1 Protein Mammalian Cell His
    Rhesus Macaque ADRB1-259R Recombinant Rhesus monkey ADRB1 Protein, His-tagged Mammalian Cell His
    Zebrafish ADRB1-6980Z Recombinant Zebrafish ADRB1 Mammalian Cell His
    Kit-0966 TR-FRET LXR beta Coactivator Assay Kit, goat N/A
    Kit-1082 Phospholipase A2 Activity Assay Kit (Fluorometric) N/A
    Kit-1112 Protein Synthesis Monitoring Assay Kit (Flow Cytometry) N/A
    Kit-1113 Cystathionine β Synthase Activity Assay Kit (Fluorometric) N/A
    Kit-2183 cAMP ADRB1 CHO-K1 GPCR Assay Kit N/A
    Kit-2184 ADRB1 CHO-K1 β-Arrestin GPCR Assay Kit N/A

    ADRB1 involved in several pathways and played different roles in them. We selected most pathways ADRB1 participated on our site, such as Adrenergic signaling in cardiomyocytes, Adrenoceptors, Amine ligand-binding receptors, which may be useful for your reference. Also, other proteins which involved in the same pathway with ADRB1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Adrenergic signaling in cardiomyocytes CACNA1SA; CACNG2A; MAPK14; Adcy4; CACNG1A; CREB1A; ATP2A2; ATF6B; PRKCA; MYL2
    Adrenoceptors ADRB3; ADRa1A; ADRA1D; ADRB1; ADRA1B; ADRB2; ADRA2A; ADRA2B; ADRA2C
    Amine ligand-binding receptors DRD3; CHRM5; ADRB3; CHRM2; DRD1; DRD5; ADRB2; ADRA2B; DRD2; TAAR1
    Calcium Regulation in the Cardiac Cell CX44.1; CHRM2; GJB4; CASQ2; GJA4; KCNB1; CX55.5; GNB3B; RGS16; GJB1
    Calcium signaling pathway CALM2A; ERBB4; PPP3CCA; HTR4; TACR3A; TACR3L; CACNA1SB; CHRM5A; CACNA1D; CAMK2G
    Class A/1 (Rhodopsin-like receptors) UTS2D; RLN2; PTGDR2; RXFP2; ADRA1D; RGR; CHRM1; CNR1; HRH3; CXCL13
    Dilated cardiomyopathy ITGA5; ITGB7; CACNA2D2; TPM4; ITGA1; ACTB; ITGA2; CACNG3; SGCD; LAMA2
    Endocytosis STAMBPB; RAB4A; ARF6B; CAPZB; RAB11BB; HSPA1B; EHD2; EPN2; CXCR1; WASH

    ADRB1 has several biochemical functions, for example, PDZ domain binding, Ras guanyl-nucleotide exchange factor activity, alpha-2A adrenergic receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ADRB1 itself. We selected most functions ADRB1 had, and list some proteins which have the same functions with ADRB1. You can find most of the proteins on our site.

    Function Related Protein
    PDZ domain binding KCNJ4; CADM1; FZD2; USHBP1; TBC1D10A; NSF; SDC2; SLC9A3R1; PTEN; CLCN3
    Ras guanyl-nucleotide exchange factor activity RASGRP3; KNDC1; RGL2; RASGRP4; RAPGEF5; RASGRP1; RASGEF1A; ADRB1; RASGEF1B; RASGEF1BB
    alpha-2A adrenergic receptor binding ADRB1; ADRBK1; UCHL1; APLP1; ADRA2C
    beta-adrenergic receptor activity ADRB3; ADRB1
    beta1-adrenergic receptor activity ADRB1
    epinephrine binding ADRB3B; ADRA2A; ADRB2A; ADRA2C; ADRB1; ADRB3A; ADRB2B; ADRB3; ADRA2B; ADRB2
    norepinephrine binding ADRB1; ADRB3B; ADRA2A; ADRB3A; ADRB2
    protein binding KRIT1; PVRL4; ALKBH3; TAF6; PYYA; SUN2; TMEM139; CCDC50; CD33; NRG4
    protein heterodimerization activity ERBB3; TAF11; BOKA; HIST1H2AA; PKNOX1; ANO9A; SRY; UBA3; SAE1; BNIP3
    receptor signaling protein activity PDCL; RAF1A; FCAR; CD3E; RAF1B; ARF1; KLK1B4; CD19; RGS12; GNAZ

    ADRB1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ADRB1 here. Most of them are supplied by our site. Hope this information will be useful for your research of ADRB1.

    MAGI2; MAGI3; Dlg4; GPRASP1; Dlg1; GPRASP2; MAGI1; GOPC; Gipc1; atenolol

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