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Official Full Name adrenergic, beta, receptor kinase 2
Background The beta-adrenergic receptor kinase specifically phosphorylates the agonist-occupied form of the beta-adrenergic and;related G protein-coupled receptors. Overall, the beta adrenergic receptor kinase 2 has 85% amino acid similarity with;beta adrenergic receptor kinase 1, with the protein kinase catalytic domain having 95% similarity. These data suggest;the existence of a family of receptor kinases which may serve broadly to regulate receptor function.
Synonyms ADRBK2; adrenergic, beta, receptor kinase 2; beta-adrenergic receptor kinase 2; BARK2; GRK3; beta-ARK-2; G-protein-coupled receptor kinase 3
    • Species :
    • Human
    • Rat
    • Zebrafish
    • Source :
    • HEK293
    • Insect Cell
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human ADRBK2-1179H Recombinant Human Adrenergic, Beta, Receptor Kinase 2, GST-tagged Insect Cell GST
    Human ADRBK2-13HCL Recombinant Human ADRBK2 lysate HEK293 N/A
    Human ADRBK2-385H Recombinant Human ADRBK2 Protein, GST-tagged Insect Cell GST
    Human ADRBK2-386H Recombinant Human ADRBK2 Protein, GST-tagged Wheat Germ GST
    Human ADRBK2-387H Recombinant Human ADRBK2 Protein, GST-tagged Wheat Germ GST
    Rat ADRBK2-547R Recombinant Rat ADRBK2 Protein Mammalian Cell His
    Zebrafish ADRBK2-7175Z Recombinant Zebrafish ADRBK2 Mammalian Cell His

    adrbk2 involved in several pathways and played different roles in them. We selected most pathways adrbk2 participated on our site, such as content, which may be useful for your reference. Also, other proteins which involved in the same pathway with adrbk2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Chemokine signaling pathway GNAI3; CCL27; JAK2; CCL8; CCL16; ITK; GNB3; CXCL6; CXCR4; DOCK2
    Corticotropin-releasing hormone CASP12; JUND; CRHBP; CRHR1; CYP21A2; CRHR2; CYP11B1; IVL; CRH; PARP1
    Endocytosis ARAP1; SH3GLB1A; AP2M1A; VPS37C; VPS37D; VPS45; VPS4A; ARAP2; RAB11FIP3; ARPC5A
    Glutamatergic synapse GNAI1; SLC1A7; GNG2; GRIA1; GRIN1; PRKACB; GRIK3; MAPK3; GRIK5; PLA2G4A
    IL-4 signaling Pathway DOK2; PAWR; ADRBK2; SPI1B; IL4R.1; HMGA1-RS1
    Morphine addiction PDE8A; PRKCA; OPRM1; GABRE; PDE2A; PRKCB; PDE1A; GNG2; PDE10A; PDE3B
    Olfactory transduction CNGA3; OR51E2; OLFR5; OLFR477; OR10A5; OLFR482; CNGA4; OR52B6; OLFR469; OLFR18
    Thromboxane A2 receptor signaling ARR3; ADRBK2; SLC9A3R1

    adrbk2 has several biochemical functions, for example, Content. Some of the functions are cooperated with other proteins, some of the functions could acted by adrbk2 itself. We selected most functions adrbk2 had, and list some proteins which have the same functions with adrbk2. You can find most of the proteins on our site.

    Function Related Protein
    G-protein coupled receptor kinase activity GRK1B; GRK4; GRK6; GRK1; GRK1A; GRK5; ADRBK2; GRK7A; ADRBK1; GRK7B
    beta-adrenergic receptor kinase activity ADRBK2; GRK5; ADRBK1; GRK6
    protein kinase activity TGFBR1A; JAK2; PTK6B; NTRK3A; ERBB4A; MAP4K6; NPR2; BRAF; SRPK1B; GSK3AB

    adrbk2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with adrbk2 here. Most of them are supplied by our site. Hope this information will be useful for your research of adrbk2.

    Opn4; HSPB1; groL; 15-deoxy-delta(12,14; ADRBK1

    Wex, E; Thaler, E; et al. A Novel Model of IgE-Mediated Passive Pulmonary Anaphylaxis in Rats. PLOS ONE 9:-(2014).
    Rahbek-Clemmensen, T; Bay, T; et al. The Serotonin Transporter Undergoes Constitutive Internalization and Is Primarily Sorted to Late Endosomes and Lysosomal Degradation. JOURNAL OF BIOLOGICAL CHEMISTRY 289:23004-23019(2014).

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