Recombinant Human AMPD3 Protein, His-tagged

• Cat.No.: AMPD3-145H
• Product Overview: Recombinant Human AMPD3 Protein (Asn552-Asn767) with N-His tag was expressed in E. coli.

Specification

• Description: This gene encodes a member of the AMP deaminase gene family. The encoded protein is a highly regulated enzyme that catalyzes the hydrolytic deamination of adenosine monophosphate to inosine monophosphate, a branch point in the adenylate catabolic pathway. This gene encodes the erythrocyte (E) isoforms, whereas other family members encode isoforms that predominate in muscle (M) and liver (L) cells. Mutations in this gene lead to the clinically asymptomatic, autosomal recessive condition erythrocyte AMP deaminase deficiency. Alternatively spliced transcript variants encoding different isoforms of this gene have been described.
• Source: E. coli
• Species: Human
• Tag: N-His
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 28.5 kDa
  Accurate Molecular Mass: 26 kDa
• Protein length: Asn552-Asn767
• Purity: > 95%
• Applications: Positive Control; Immunogen; SDS-PAGE; WB.
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
• Storage Buffer: PBS, pH7.4, containing 0.01% SKL, 1 mM DTT, 5% Trehalose and Proclin300.
• Reconstitution: Reconstitute in sterile water to a concentration of 0.1-1.0 mg/mL. Do not vortex.

Gene Information

• Gene Name: AMPD3 adenosine monophosphate deaminase 3 [ Homo sapiens (human) ]
• Official Symbol: AMPD3
• Synonyms: AMPD3; adenosine monophosphate deaminase 3; AMP deaminase 3; AMP aminohydrolase; adenosine monophosphate deaminase (isoform E); erythrocyte AMP deaminase; erythrocyte type AMP deaminase; erythrocyte-specific AMP deaminase; myoadenylate deaminase; EC 3.5.4.6
• Gene ID: 272
• mRNA Refseq: NM_000480
• Protein Refseq: NP_000471
• MIM: 102772
• UniProt ID: Q01432