anapc10

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anapc10

Official Full Name anaphase promoting complex subunit 10
Background ANAPC10 is a core subunit of the anaphase-promoting complex (APC), or cyclosome, a ubiquitin protein ligase that is;essential for progression through the cell cycle. APC initiates sister chromatid separation by ubiquitinating the;anaphase inhibitor securin (PTTG1; MIM 604147) and triggers exit from mitosis by ubiquitinating cyclin B (CCNB1; MIM;123836), the activating subunit of cyclin-dependent kinase-1 (CDK1; MIM 116940) (summary by Wendt et al., 2001 (PubMed;11524682)).
Synonyms ANAPC10; anaphase promoting complex subunit 10; anaphase-promoting complex subunit 10; APC10; DKFZP564L0562; DOC1; cyclosome subunit 10
    • Species :
    • Chicken
    • Human
    • Mouse
    • Zebrafish
    • Source :
    • E.coli
    • HEK293
    • HEK293T
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • Myc/DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human ANAPC10-541H Recombinant Human ANAPC10 protein, GST-tagged Wheat Germ GST
    Human ANAPC10-5701H Recombinant Human ANAPC10 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
    Human ANAPC10-8871HCL Recombinant Human ANAPC10 293 Cell Lysate HEK293 N/A
    Human ANAPC10-9634H Recombinant Human ANAPC10, His-tagged E.coli His
    Mouse Anapc10-1619M Recombinant Mouse Anapc10 Protein, Myc/DDK-tagged HEK293T Myc/DDK
    Mouse ANAPC10-1620M Recombinant Mouse ANAPC10 Protein Mammalian Cell His
    Chicken ANAPC10-1845C Recombinant Chicken ANAPC10 Mammalian Cell His
    Zebrafish ANAPC10-8243Z Recombinant Zebrafish ANAPC10 Mammalian Cell His
    Zebrafish ANAPC10-8244Z Recombinant Zebrafish ANAPC10 Mammalian Cell His

    anapc10 involved in several pathways and played different roles in them. We selected most pathways anapc10 participated on our site, such as APC-Cdc20 mediated degradation of Nek2A, APC/C-mediated degradation of cell cycle proteins, APC/C:Cdc20 mediated degradation of Cyclin B, which may be useful for your reference. Also, other proteins which involved in the same pathway with anapc10 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    APC-Cdc20 mediated degradation of Nek2A ANAPC10; NEK2; UBE2C
    APC/C-mediated degradation of cell cycle proteins PSMD9; NEK2; CDK2; AURKB; UBE2C; PSMA8; PSMD10; ANAPC10; PSMD5; PSMD14
    APC/C:Cdc20 mediated degradation of Cyclin B ANAPC10; UBE2C
    APC/C:Cdc20 mediated degradation of Securin PSME3; PSMD5; PSMD10; UBE2C; ANAPC10; PSMD14; PSMA8; PSMD9
    APC/C:Cdc20 mediated degradation of mitotic proteins UBE2C; NEK2; PSMD14; PSMD5; PSMA8; PSMD9; PSMD10; ANAPC10; PSME3
    APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 ANAPC10; PSMD10; UBE2C; PSMD9; PSMD5; PSMA8; PSMD14; PSME3; AURKB
    APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint PSMA8; ANAPC10; PSMD9; PSMD10; PSMD14; UBE2C; PSME3; PSMD5; NEK2
    Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins UBE2C; NEK2; PSMD14; ANAPC10; PSMA8; PSMD10; PSMD9; PSME3; PSMD5

    anapc10 has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by anapc10 itself. We selected most functions anapc10 had, and list some proteins which have the same functions with anapc10. You can find most of the proteins on our site.

    Function Related Protein

    anapc10 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with anapc10 here. Most of them are supplied by our site. Hope this information will be useful for your research of anapc10.

    CDC16; Cdc23; Cdc16; Cdc26; CDC23; ANAPC16; Cdc20; Bub1b; MAPK8IP2; PTBP3

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