ANG Protein

September 27-30, 2022

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Booth #336

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ANG

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ANG

Official Full Name Angiogenin
Background Angiogenin (Ang) also known as ribonuclease 5 is a protein that in humans is encoded by the ANG gene. Angiogenin is a potent stimulator of new blood vessel formation. It hydrolyzes cellular tRNAs resulting in decreased protein synthesis and is similar to pancreatic ribonuclease. Hooper et al. (2003) reviewed the evidence that angiogenins are involved in host defense and noted that inflammation provokes upregulated ANG mRNA expression in liver and an increase in detectable ANG protein in serum. Weremowicz et al. (1989, 1990) assigned the human angiogenin gene to chromosome 14q11.
Synonyms Angiogenin; Ang; ribonuclease 5
    • Species :
    • Cattle
    • Chicken
    • Human
    • Mouse
    • Pig
    • Rat
    • Source :
    • E.coli
    • E.Coli or Yeast
    • HEK293
    • HEK293T
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • T7
    • MYC/DDK
    • Myc
    • DDK
    • N/A
    • N-His
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human ANG-2629H Recombinant Human Angiogenin, Ribonuclease, RNase A Family, 5 E.coli N/A
    Human ANG-507H Recombinant Human angiogenin, ribonuclease, RNase A family, 5, His-tagged E.coli His
    Human ANG-5108H Recombinant Human ANG, His-tagged E.coli His
    Human ANG-548H Recombinant Human ANG protein, GST-tagged Wheat Germ GST
    Human ANG-9641H Recombinant Human ANG, His-tagged E.coli His
    Mouse ANG-1627M Recombinant Mouse ANG Protein Mammalian Cell His
    Mouse Ang-3453M Recombinant Mouse Ang, His-tagged E.Coli or Yeast His
    Mouse Ang-519M Recombinant Mouse Ang protein, His-tagged E.coli His
    Mouse Ang-520M Recombinant Mouse Ang protein, His & GST-tagged E.coli His/GST
    Rat Ang-522R Recombinant Rat Ang protein, His & T7-tagged E.coli His/T7
    Chicken ANG-6811C Recombinant Chicken ANG Mammalian Cell His
    Cattle ANG-518C Recombinant Cattle ANG protein, His-tagged E.coli His
    Pig ANG-521P Recombinant Pig ANG protein, His-tagged E.coli His
    Human ANG-20HCL Recombinant Human ANG lysate HEK293 N/A
    Human ANG-148H Recombinant Human ANG Protein, His-tagged E.coli N-His
    Mouse Ang-149M Recombinant Mouse Ang Protein, His-tagged E.coli N-His
    Human ANG-1424H Recombinant Human ANG Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
    Human ANG-2082H Recombinant Human ANG Protein, MYC/DDK-tagged HEK293 Myc/DDK
    Human ANG-27314TH Recombinant Human ANG Wheat Germ N/A
    Mouse Ang-602M Recombinant Mouse Ang Protein, MYC/DDK-tagged HEK293T MYC/DDK

    ANG involved in several pathways and played different roles in them. We selected most pathways ANG participated on our site, such as Adherens junctions interactions, Cell junction organization, Cell-Cell communication, which may be useful for your reference. Also, other proteins which involved in the same pathway with ANG were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Adherens junctions interactions CDH5; CDH17; CDH9; CDH18; JUPA; CTNNB1; CDH10A; CADM2; CDH8; CDH2
    Cell junction organization CDH2; CDH12; CLDN7; CDH10A; CDH6; CLDN4; CLDN16; CD151; PVRL1A; ITGB1B.1
    Cell-Cell communication CADM2B; FBLIM1; CLDN20; CDH9; DSCAMA; CDH10A; KIRREL2; FERMT2; LIMS1; CTNND1
    Cell-cell junction organization CDH5; CDH13; PVRL1A; CLDN23; JUPA; CDH7; CDH12A; CDH17; CADM2A; CDH8

    ANG has several biochemical functions, for example, DNA binding, actin binding, copper ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ANG itself. We selected most functions ANG had, and list some proteins which have the same functions with ANG. You can find most of the proteins on our site.

    Function Related Protein
    DNA binding HNF1A; ZNF180; MYCN; ZBTB25; ZNF19; HER5; ZFP143; RCOR1; ZBTB8B; MEIOB
    actin binding LMOD1; CAPZB; KLHL1; KLHL2; MSNB; NRAP; ESPN; EMD; SPIRE1A; NCALD
    copper ion binding S100A12; DCT; F8; SERPINB1A; MT1; MT3; PRND; SOD1; LOXL3A; P2RX2
    endonuclease activity ZC3H12A; EME1; ENDOG; EME2; EXOG; SMG6; FEN1; EAR5; EAR3; RNASE2
    heparin binding MSTN; COL13A1; FGFRL1; ANG; SERPINA5; CCL2; VEGFB; Itgam&Itgb2; HBEGF; CRISPLD2
    peptide binding HCRTR1; GPR22; AVPR1B; MME; THOP1; GNRHR; PPIA; NPFFR2; MAS1; CTSL2
    protein binding FAM122A; CDH5; LGR6; MFAP1; PTPRD; HIST1H4I; RCOR3; DTNA; ZNF114; FUS
    protein homodimerization activity CHUK; TENM3; GPD1A; CITED1; TRIM37; MGST1; DRD2; SMAD3; BCL2A1; PRMT2
    rRNA binding DIEXF; MRPL20; RPS5; RPS18; RPL23A; RPL8; TLR13; PPAN; RPS11; DDX28
    receptor binding FYNB; TNFSF9; HFE; WNT11R; WNT7A; FIS1; RND1; ITGA1; INHA; CNPY3
    ribonuclease activity RNASE3; EAR2; RSFR; RNASE2; RNASEH1; RNASEH2A; EAR14; ANG4; RNASET2B; EAR4

    ANG has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ANG here. Most of them are supplied by our site. Hope this information will be useful for your research of ANG.

    ACTN2; FST; RNH1; TDGF1; FST; PTEN; ATP6AP1; ABCG8

    Berger, JM; Vaillant, N; et al. PCSK9-deficiency does not alter blood pressure and sodium balance in mouse models of hypertension. ATHEROSCLEROSIS 239:252-259(2015).
    Glenn, DJ; Cardema, MC; et al. Cardiac steatosis potentiates angiotensin II effects in the heart. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY 308:H339-H350(2015).

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