Recombinant Mouse Ang Protein, His-tagged Ang-149M

Recombinant Mouse Ang Protein, His-tagged

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Cat.No. : Ang-149M Optional Service: Optional requirements on this protein
Product Overview : Recombinant Mouse Ang Protein (Val98-Trp436) with N-His tag was expressed in E. coli.
Description : This gene encodes a member of the pancreatic ribonuclease A superfamily and is a potent inducer of neovascularization. The encoded protein is a secreted multifunctional tRNA-specific ribonuclease that promotes angiogenesis in response to angiogenetic stimuli such as hypoxia, mediates stress-induced translational repression by cleaving cellular tRNAs, stimulates cell proliferation by mediating rRNA transcription in prostate cancer cells, and is involved in neurite pathfinding. This gene resides in a cluster of highly related genes. It shares dual promoters and 5' exons with the ribonuclease, RNase A family 4 gene. Two alternatively spliced variants, with different 5' exons but the same coding exon, have been identified. Multiple pseudogenes have been found for this gene.
Source : E. coli
Species : Mouse
Tag : N-His
Form : Freeze-dried powder
Molecular Mass : Predicted Molecular Mass: 39.8 kDa
Protein length : Val98-Trp436
Purity : > 97%
Applications : Positive Control; Immunogen; SDS-PAGE; WB.
Stability : The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Storage : Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
Storage Buffer : PBS, pH7.4, containing 0.01% SKL, 1 mM DTT, 5% Trehalose and Proclin300.
Reconstitution : Reconstitute in sterile water to a concentration of 0.1-1.0 mg/mL. Do not vortex.
SDS-PAGE :

Gene Name : Ang angiogenin, ribonuclease, RNase A family, 5 [ Mus musculus (house mouse) ]
Official Symbol : Ang
Synonyms : ANG; angiogenin, ribonuclease, RNase A family, 5; angiogenin; RNase 5; angiogenin-1; ribonuclease 5; angiogenin, ribonuclease A family, member 1; Ang1; Rnase5; Rnase5a; AI385586
Gene ID : 11727
mRNA Refseq : NM_001161731
Protein Refseq : NP_001155203
UniProt ID : P20918
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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