Recombinant Human ANG, His-tagged

• Cat.No.: ANG-5108H
• Product Overview: Recombinant human ANG protein, fused to His-tag at N-terminus, was expressed in E.coli.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Description: ANG, as known as Angiogenin, belongs to RNase A family. This protein is an exceedingly potent mediator of new blood vessel formation. It hydrolyzes cellular tRNAs resulting in decreased protein synthesis and is similar to pancreatic ribonuclease.
• Form: Liquid. 20mM Tris-HCl buffer (pH8.0) containing 10% glycerol 0.4M Urea
• Molecular Mass: 16.4 kDa(144aa)
• AA Sequence: MGSSHHHHHH SSGLVPRGSH MQDNSRYTHF LTQHYDAKPQ GRDDRYCESI MRRRGLTSPC KDINTFIHGN KRSIKAICEN KNGNPHRENL RISKSSFQVT TCKLHGGSPW PPCQYRATAG FRNVVVACEN GLPVHLDQSI FRRP
• Purity: >90% by SDS - PAGE
• Applications: SDS-PAGE
• Storage: Can be stored at +4centigrade short term (1-2 weeks). For long term storage, aliquot and store at -20centigrade or -70centigrade. Avoid repeated freezing and thawing cycles.
• Concentration: 0.5mg/ml (determined by Bradford assay)

Gene Information

• Gene Name: ANG angiogenin, ribonuclease, RNase A family, 5 [ Homo sapiens ]
• Official Symbol: ANG
• Synonyms: ANG; angiogenin, ribonuclease, RNase A family, 5; angiogenin; RNASE5; RNase 5; ribonuclease 5; epididymis luminal protein 168; ALS9; HEL168; RNASE4; MGC22466; MGC71966
• Gene ID: 283
• mRNA Refseq: NM_001097577
• Protein Refseq: NP_001091046
• MIM: 105850
• UniProt ID: P03950
• Chromosome Location: 14q11.1-q11.2
• Function: DNA binding; actin binding; copper ion binding; endonuclease activity; heparin binding; hydrolase activity; pancreatic ribonuclease activity; peptide binding; protein binding; rRNA binding; receptor binding; ribonuclease activity