ARL3
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Official Full Name
ADP-ribosylation factor-like 3 -
Overview
ADP-ribosylation factor-like 3 is a member of the ADP-ribosylation factor family of GTP-binding proteins. ARL3 binds guanine nucleotides but lacks ADP-ribosylation factor activity. -
Synonyms
ARL3;ADP-ribosylation factor-like 3;ADP-ribosylation factor-like protein 3;ARFL3;ARF-like 3
Recombinant Proteins
- Human
- Rat
- Zebrafish
- Mouse
- E.coli
- E.Coli/Yeast
- Mammalian Cells
- Wheat Germ
- HEK293
- In Vitro Cell Free System
- GST
- His
- Non
- DDK
- Myc
- Avi
- Fc
Involved Pathway
ARL3 involved in several pathways and played different roles in them. We selected most pathways ARL3 participated on our site, such as Assembly of the primary cilium,Cargo trafficking to the periciliary membrane,Organelle biogenesis and maintenance, which may be useful for your reference. Also, other proteins which involved in the same pathway with ARL3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Organelle biogenesis and maintenance | BBS9,IFT43,FLR,WDR35,PTCD3,WDR34,NPHP1,MTFMT,MRPL3,GABPB1 |
| Cargo trafficking to the periciliary membrane | CCT8,ARF4A,PROL1,LZTFL1,PKD1,CNGA5,BBS1,EXOC3,CCT2,RHOL |
| Trafficking of myristoylated proteins to the cilium | RP2,CYS1,UNC119B,NPHP3,UNC119.1 |
| Assembly of the primary cilium | RAB3IP,TMEM67,IFT43,TTBK2,EXOC3,CKAP5,CSNK1D,DCTN2,TCTEX1D1,CNGA2 |
Protein Function
ARL3 has several biochemical functions, for example, GDP binding,GTP binding,GTPase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by ARL3 itself. We selected most functions ARL3 had, and list some proteins which have the same functions with ARL3. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | NDFIP1,CAV2,RBM5,DAO,SMARCAL1,CBX4,C22orf13,BNIP3,PQBP1,SSX5 |
| GTPase activity | DNM1L,TUBA3D,RAP2A,TUBB5,MXE,GEM,RHOT1,MFN2,GTPBP4,RAB34 |
| microtubule binding | VAPB,ZFP207,DPYSL5A,MACF1,CRIPT,CETN1,FMR1,KRIT1,GLI1,BIRC5 |
| GDP binding | RAB2A,GNAI1,RAB35,RAB17,RAB12,TRIM23,RAB8B,ARF1,RAB31,SRP54B |
| metal ion binding | RNF216,JUB,SOBP,TRERF1,ZNF134,ZNF18,RXFP1,GTF3A,RNF128A,NT5M |
| GTP binding | EIF5B,RAB8B,RAB11AL,RHOD,EEF2A.1,LSG1,DRG2,SRPR,SEPT1,RAB2A |
Interacting Protein
ARL3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ARL3 here. Most of them are supplied by our site. Hope this information will be useful for your research of ARL3.
UNC119;PDE6D;RP2;RP1L1;BSND;TBCD;TP53;TLE1;RIF1;UBR1
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