|Official Full Name||activating transcription factor 6 beta|
|Background||The protein encoded by this gene is a transcription factor in the unfolded protein response (UPR) pathway during ER stress. Either as a homodimer or as a heterodimer with ATF6-alpha, the encoded protein binds to the ER stress response element, interacting with nuclear transcription factor Y to activate UPR target genes. The protein is normally found in the membrane of the endoplasmic reticulum; however, under ER stress, the N-terminal cytoplasmic domain is cleaved from the rest of the protein and translocates to the nucleus. Two transcript variants encoding different isoforms have been found for this gene.|
|Synonyms||ATF6B; activating transcription factor 6 beta; cAMP responsive element binding protein like 1 , CREBL1; cyclic AMP-dependent transcription factor ATF-6 beta; G13; G13 protein; ATF 6 beta; ATF6-beta; ATF6B_HUMAN; ATF6beta; cAMP response element binding protein related protein; cAMP response element-binding protein-related protein; cAMP responsive element binding protein like 1; cAMP-dependent transcription factor ATF-6 beta; cAMP-responsive element-binding protein-like 1; CREB L1; Creb related protein; CREB RP; Creb-rp; CREBL 1; CREBL1; Crebrp; Cyclic AMP dependent transcription factor ATF 6 beta; Cyclic AMP dependent transcription factor ATF6 beta; FLJ10066; OTTHUMP00000029432; OTTHUMP00000029433; Processed cyclic AMP-dependent transcription factor ATF-6 beta; Protein G13; Creb-related protein; cAMP responsive element binding protein-like 1|
|Species||Cat.#||Product name||Source (Host)||Tag||Protein Length||Price|
atf6b involved in several pathways and played different roles in them. We selected most pathways atf6b participated on our site, such as Adrenergic signaling in cardiomyocytes, Alcoholism, Aldosterone synthesis and secretion, which may be useful for your reference. Also, other proteins which involved in the same pathway with atf6b were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
|Pathway Name||Pathway Related Protein|
|Adrenergic signaling in cardiomyocytes||PIK3CA; PLCB4; PPP2R2D; PPP2R5EB; ATP2B1; MAPK13; Adcy4; CACNB1; PPP1CAA; ADRA1BB|
|Alcoholism||HIST2H2BE; ATF4; NTRK2; H2AFJ; ATF6B; GNB1; CAMKK2; HIST1H4M; HIST1H2BL; H3F3B|
|Aldosterone synthesis and secretion||KCNK9; AGTR1; PLCB1; CREB3L2; CALM3; NR4A2; AGTR1A; CALML5; ATF6B; PRKACA|
|Amphetamine addiction||PRKCA; PDYN; PRKCB; ATF2; PPP3CA; DRD1A; CAMK2B; CAMK2D; GRIA4; PRKACG|
|Cocaine addiction||PRKACB; GRM3; PRKACG; GPSM1; DRD1; DRD1A; CREB3L2; CREB3L4; CREB3; GNAI2|
|Dopaminergic synapse||GNB1; GSK3B; DRD5; CAMK2G; PLCB2; DRD1; MAPK13; TH; GNGT2; SLC6A3|
|Estrogen signaling pathway||GABBR1; FOS; MAP2K2; ESR1; PIK3CA; CREB5; GNAQ; PLCB3; MMP2; HSPA2|
|G1 to S cell cycle control||TFDP1B; E2F6; MYT1; ATF6B; CDKN1C|
atf6b has several biochemical functions, for example, cAMP response element binding, protein binding, sequence-specific DNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by atf6b itself. We selected most functions atf6b had, and list some proteins which have the same functions with atf6b. You can find most of the proteins on our site.
|cAMP response element binding||CREB3L3; CREB3L1; JUN; CREB3L2; CREB3L3A; ATF6; CREB3; CREB1; CREB3L3L; HMGA2|
|protein binding||SKIV2L2; VIPR1; GTSE1; GRIK3; FHL3; C16orf48; HILPDA; RAP2B; IL28RA; SLC26A6|
|sequence-specific DNA binding||CTCFL; NKX6-1; FOXA3; ZNF396; HIC1; GATA5; NR5A1A; TBX3; HOXB4; RAX2|
|transcription factor activity, sequence-specific DNA binding||BCL6; ESRRGA; TFE3; CREB3L3L; HOXD3A; ZNF182; TCF4; NME2; EGR2A; MTF1|
|transcription regulatory region DNA binding||LEF1; SOX17; TCF7; CBX4; RFX6; TNF; GRHL1; SOX5; CCNT1; IKZF1|
atf6b has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with atf6b here. Most of them are supplied by our site. Hope this information will be useful for your research of atf6b.
p27958-pro_0000037575; CDK6; ysuB; proP16; proP17