ATP2A2
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Official Full Name
ATPase, Ca++ transporting, cardiac muscle, slow twitch 2
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Synonyms
Serca2; SercaII;
- Involved Pathway
- Protein Function
- Interacting Protein
- ATP2A2 Related Articles
ATP2A2 involved in several pathways and played different roles in them. We selected most pathways ATP2A2 participated on our site, such as Calcium signaling pathway, cGMP-PKG signaling pathway, cAMP signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with ATP2A2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Calcium signaling pathway | ERBB4A;ORAI1;CALM3;PHKA1;PPIF;AGTR1;CACNA1G;RYR1;PTGER1C |
| cGMP-PKG signaling pathway | PRKG1;PIK3CA;MAP2K1;ATP1A1;KCNJ8;ATP1B3;PIK3CB;KCNMB4;NFATC1 |
| cAMP signaling pathway | CNGA1;TNNI3;OXTR;SUCNR1;GLI3;BDNF;MAP2K1;FFAR2;HCN4 |
| Cardiac muscle contraction | ATP1B1;CACNB3;ATP1B1A;COX5B2;ACTC1B;TPM4B;UQCRC2B;ATP1A3B;COX5A |
| Adrenergic signaling in cardiomyocytes | PPP1CB;RYR2;GNAIA;PLCB2;ATP1A1A.1;VMHCL;ATF4;PPP2R1B;GNAS |
| Thyroid hormone signaling pathway | ATP1B2;DIO1;ATP1B3;PIK3R2;MAPK3;SLC16A10;ATP1B1;PIK3CA;ATP1B4 |
| Pancreatic secretion | PLA2G12B;RAC1;Car2;PLA2G3;PLA2G12A;CPA2;PLA2G5;CTRL;AMY2A4 |
| Alzheimers disease | LRP1;BACE2;CALML3;CASP9;APOE;NDUFA5;CALM4;PPP3CC;ATP5J |
| Hypertrophic cardiomyopathy (HCM) | TNF;ITGB5;CACNG6;TPM3;PRKAB2;ACTB;ITGA8;ITGB1;PRKAG2 |
| Arrhythmogenic right ventricular cardiomyopathy (ARVC) | ATP2A2;ITGA9;SGCB;LAMA2;CACNG3;ITGB1;CACNG8;DMD;DES |
| Dilated cardiomyopathy | CACNB4;MYH7;ACTG1;PLN;ACTC1;ITGA4;ITGA2;ITGA8;CACNG1 |
ATP2A2 has several biochemical functions, for example, ATP binding, S100 protein binding, calcium ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ATP2A2 itself. We selected most functions ATP2A2 had, and list some proteins which have the same functions with ATP2A2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| ATP binding | PLK2B;EPHA2;ABCC8;GKUP;YTHDC2;PMELA;PIF1;WRN;NUBP1 |
| S100 protein binding | ANXA2;DDX1;S100A11;AHNAK;S100A1;AGER;KCNK3;S100A6;S100B |
| calcium ion binding | PKD2L2;PVALB5;NOTCH4;APCS;RPH3AL;C1rb;THBS3;ACTN3B;PLCG1 |
| calcium-transporting ATPase activity | ATP2B1;ATP2A3;ATP2C1;ATP2A1L;ATP2A1;ATP2A2;ATP2B4;ATP2A2B;ATP2B1B |
| calcium-transporting ATPase activity involved in regulation of cardiac muscle cell membrane potential | |
| enzyme binding | SCN5A;HIST1H2AG;ECM1;CD4;TSPAN10;PIAS1;SNRPD3;PUS7;TOP2A |
| lutropin-choriogonadotropic hormone receptor binding | |
| protein C-terminus binding | TRIM3;DST;CTBP1;SNTG1;MYO1C;AXIN1;TAF13;MPDZ;HSPG2 |
| protein binding | OSTC;PLK4;HDC;SPAST;TBX1;EMD;LDOC1;STX1A;UHRF1 |
ATP2A2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ATP2A2 here. Most of them are supplied by our site. Hope this information will be useful for your research of ATP2A2.
MYC; OPRD1; EGFR; CANX; ILK; env; PTP4A3; TNF; TNFRSF1A; TNFRSF1B; TRADD; PPP5C; TRAF6
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