ATP2A2

  • Official Full Name

    ATPase, Ca++ transporting, cardiac muscle, slow twitch 2

  • Synonyms

    Serca2; SercaII;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Human
  • Mouse
  • Rat
  • E.coli
  • HEK293
  • In Vitro Cell Free System
  • Mammalian cell
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
  • His|GST
  • N/A
  • N
  • 10×His
  • Strep II
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human ATP2A2-2585H Recombinant Human ATP2A2, His-tagged E.coli His 320-700aa
Human ATP2A2-970H Recombinant Human ATP2A2 protein, GST-tagged Wheat Germ GST
Human ATP2A2-8609HCL Recombinant Human ATP2A2 293 Cell Lysate HEK293 N/A
Human ATP2A2-1245HF Recombinant Full Length Human ATP2A2 Protein, GST-tagged In Vitro Cell Free System GST 997 amino acids
Human ATP2A2-463H Recombinant Human ATP2A2 Protein, His/GST-tagged E.coli His/GST Ile315~Met756
Human ATP2A2-266H Recombinant Human ATP2A2 Protein, His-tagged E.coli N-His Ile315-Met756
Human ATP2A2-2684H Recombinant Human ATP2A2 protein, His-tagged E.coli His 314-580 aa
Human ATP2A2-1268H Recombinant Human ATP2A2 Protein (M1-S1042 end), Strep II/His tagged Mammalian cell Strep II/His M1-S1042 end
Human ATP2A2-2565H Recombinant Human ATP2A2 protein, His-tagged E.coli His 314-756aa
Human ATP2A2-0288H Recombinant Human ATP2A2 Protein (Ile315-Met756), N-His-tagged E.coli N-His Ile315-Met756
Human ATP2A2-14H Recombinant Human ATP2A2-eGFP Protein (M1-S1042 end), N-10×His/Strep II-tagged Mammalian cell N-10×His/Strep II M1-S1042 end
Mouse ATP2A2-2121M Recombinant Mouse ATP2A2 Protein Mammalian Cell His
Mouse ATP2A2-855M Recombinant Mouse ATP2A2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse ATP2A2-855M-B Recombinant Mouse ATP2A2 Protein Pre-coupled Magnetic Beads HEK293
Rat ATP2A2-859R Recombinant Rat ATP2A2 Protein Mammalian Cell His
Rat ATP2A2-515R-B Recombinant Rat ATP2A2 Protein Pre-coupled Magnetic Beads HEK293
Rat ATP2A2-515R Recombinant Rat ATP2A2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Chicken ATP2A2-4692C Recombinant Chicken ATP2A2 Mammalian Cell His
Chicken ATP2A2-4693C Recombinant Chicken ATP2A2 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • Other Resource

ATP2A2 involved in several pathways and played different roles in them. We selected most pathways ATP2A2 participated on our site, such as Calcium signaling pathway, cGMP-PKG signaling pathway, cAMP signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with ATP2A2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Calcium signaling pathwayPPP3R1;PHKG1;HTR2C;CAMK2B;PTAFR;GNAQ;CAMK2A;P2RX3;CAMK4
cGMP-PKG signaling pathwayPIK3CG;PPP3CA;VDAC3;RGS2;INS2;SLC8A2;ATP2A1;NFATC1;CALML3
cAMP signaling pathwayF2R;GRIA1;NFKBIA;PDE4D;GIPR;MAP2K2;ATP1B3;GNAI3;PDE4B
Cardiac muscle contractionCOX7A2;UQCRH;MYL4;MYH7;ATP1B4;ATP1B1A;UQCRB;UQCR10;CACNB4
Adrenergic signaling in cardiomyocytesPPP2R5E;CACNA2D2;ATP1A3A;PPP2CB;KCNQ1;ATP1B1;CACNA1C;CAMK2G1;CACNG4
Thyroid hormone signaling pathwayKRAS;ATP1A3;RXRG;PFKFB2;HDAC1;MED12L;PLCB4;CCND1;ATP1A4
Pancreatic secretionPLA2G10;PLCB3;Cel;RAP1A;TRPC1;CELA3A;KCNMA1;PLA2G2D;ATP1A4
Alzheimers diseaseNAE1;NDUFV2;NDUFB3;COX7A2;NDUFC2;UQCRC1;NDUFA5;NDUFC2-KCTD14;UQCRFS1
Hypertrophic cardiomyopathy (HCM)ATP2A2;ITGB3;CACNB1;ACTG1;SGCA;ITGA6;DAG1;IL6;IGF1
Arrhythmogenic right ventricular cardiomyopathy (ARVC)ITGA8;TCF7L2;ITGB1;CACNG6;ACTN3;LEF1;ITGB8;CACNA2D1;ITGA7
Dilated cardiomyopathySGCG;CACNG2;ITGA1;ITGB3;ITGA6;CACNB1;ITGB1;GNAS;CACNG7

ATP2A2 has several biochemical functions, for example, ATP binding, S100 protein binding, calcium ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ATP2A2 itself. We selected most functions ATP2A2 had, and list some proteins which have the same functions with ATP2A2. You can find most of the proteins on our site.

Function Related Protein
ATP bindingMAP3K14;WEE2;MAP3K4;SMCHD1;MYO6B;MYHZ1.2;CKMT1;ATP2B3B;LCK
S100 protein bindingAHNAK;ANXA11;S100A6;ATP2A2;EZR;AGER;DDX1;FGF1A;S100B
calcium ion bindingF9;TLL2;CLSTN1;MMP20;GSNA;SLC24A2;GUCA1E;SPOCK3;CABP1
calcium-transporting ATPase activityATP2C2;ATP2B3B;ATP2A3;ATP2B2;ATP2B3A;ATP2A2A;ATP2B4;ATP2A1;ATP2A2B
calcium-transporting ATPase activity involved in regulation of cardiac muscle cell membrane potential
enzyme bindingHIST1H2AG;APOA5;CDC20;KRT79;TRIO;HNRNPUL1;TBP;CBX4;SUPT5H
lutropin-choriogonadotropic hormone receptor binding
protein C-terminus bindingSDCBP2;ITGB3BP;ATXN2;PPM1A;CTBP1;CSK;PDZD11;ABL1;PRKAA1
protein bindingIRF1;RERG;NCAPH2;WDR20;SEC14L4;PTPRG;CD177;TBX18;RSG1

ATP2A2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ATP2A2 here. Most of them are supplied by our site. Hope this information will be useful for your research of ATP2A2.

MYC; OPRD1; EGFR; CANX; ILK; env; PTP4A3; TNF; TNFRSF1A; TNFRSF1B; TRADD; PPP5C; TRAF6

Research Area

Related articles

Powell, H; Affolter, VK; et al. Combined decongestive therapy including equine manual lymph drainage to assist management of chronic progressive lymphoedema in draught horses. EQUINE VETERINARY EDUCATION 24:81-89(2012).
Dally, S; Corvazier, E; et al. Multiple and diverse coexpression, location, and regulation of additional SERCA2 and SERCA3 isoforms in nonfailing and failing human heart. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY 48:633-644(2010).
  • Q&As
  • Reviews

Q&As (6)

Ask a question
Are ATP2A2 recombinant protein mutations associated with human nervous system related diseases? 01/17/2022

Mutations in the recombinant ATP2A2 protein are associated with several nervous system related diseases, such as neurodegenerative diseases and neurodysregulation.

What are the structural features of the recombinant ATP2A2 protein? 10/16/2021

ATP2A2 protein is a calcium pump protein containing multiple membrane channels and ATP-binding sites for the regulation of intracellular calcium homeostasis.

Is the expression and function of recombinant ATP2A2 protein regulated in the nervous system? 08/23/2021

Yes, the expression and function of ATP2A2 recombinant protein in the nervous system are regulated by complex mechanisms, including endogenous signaling pathways and cell-to-cell interactions.

Is there any polymorphic variation or mutation in ATP2A2 recombinant protein? 02/27/2021

Yes, there are polymorphic variations or mutations in ATP2A2 recombinant protein, which may be related to the susceptibility and pathogenesis of nervous system related diseases.

What is the function of ATP2A2 recombinant protein in the nervous system? 07/10/2020

The recombinant ATP2A2 protein is responsible for regulating calcium homeostasis and maintaining nerve cell communication in the nervous system.

Does the recombinant ATP2A2 protein interact with other proteins? 01/21/2020

The recombinant ATP2A2 protein interacts with other membrane proteins, such as calcium channels and transporters, to regulate the function of nerve cells.

Customer Reviews (3)

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Reviews
08/09/2020

    Because ATP2A2 has a short half-life and high clearance, it better prevents drug accumulation in the body, thereby reducing the risk of side effects caused by long-term use.

    07/28/2019

      The production process of ATP2A2 focuses on harmonious coexistence with nature, realizes zero pollution in the production process, and brings a positive impact on the environment.

      03/25/2019

        It can maintain stable performance even in extremely harsh environments, which is a rare quality.

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