ATP2B3
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Official Full Name
ATPase, Ca++ transporting, plasma membrane 3
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Background
The protein encoded by this gene belongs to the family of P-type primary ion transport ATPases characterized by the formation of an aspartyl phosphate intermediate during the reaction cycle. These enzymes remove bivalent calcium ions from eukaryotic cells against very large concentration gradients and play a critical role in intracellular calcium homeostasis. The mammalian plasma membrane calcium ATPase isoforms are encoded by at least four separate genes and the diversity of these enzymes is further increased by alternative splicing of transcripts. The expression of different isoforms and splice variants is regulated in a developmental, tissue- and cell type-specific manner, suggesting that these pumps are functionally adapted to the physiological needs of particular cells and tissues. This gene encodes the plasma membrane calcium ATPase isoform 3. Alternatively spliced transcript variants encoding different isoforms have been identified. -
Synonyms
ATP2B3; ATPase, Ca++ transporting, plasma membrane 3; plasma membrane calcium-transporting ATPase 3; plasma membrane calcium transporting ATPase 3; PMCA3; plasma membrane calcium pump; plasma membrane calcium ATPase; PMCA3a;
Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
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Human | ATP2B3-267H | Recombinant Human ATP2B3 Protein, His-tagged | E.coli | N-His |
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Mouse | ATP2B3-12M | Recombinant Mouse ATP2B3 Protein, His-tagged | E.coli | His |
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Rat | ATP2B3-519R | Recombinant Rat ATP2B3 Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi |
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Rat | ATP2B3-519R-B | Recombinant Rat ATP2B3 Protein Pre-coupled Magnetic Beads | HEK293 |
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Rat | ATP2B3-863R | Recombinant Rat ATP2B3 Protein | Mammalian Cell | His |
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- ATP2B3 Related Articles
Talarico, EF; et al. Plasma membrane calcium-ATPase isoform four distribution changes during corneal epithelial wound healing. MOLECULAR VISION 16:2259-2272(2010).
Ramoino, P; Milanese, M; et al. gamma-Amino butyric acid (GABA) release in the ciliated protozoon Paramecium occurs by neuronal-like exocytosis. JOURNAL OF EXPERIMENTAL BIOLOGY 213:1251-1258(2010).
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