Recombinant Mouse ATP2B3 Protein, His-tagged

• Cat.No.: ATP2B3-12M
• Product Overview: Recombinant Mouse ATP2B3 Protein, fused to His-tag, was expressed in E. coli.

Specification

• Description: Predicted to enable P-type calcium transporter activity involved in regulation of presynaptic cytosolic calcium ion concentration and PDZ domain binding activity. Predicted to be involved in calcium ion export across plasma membrane and regulation of cytosolic calcium ion concentration. Predicted to be located in membrane raft; parallel fiber; and plasma membrane. Predicted to be active in GABA-ergic synapse; glutamatergic synapse; and intracellular membrane-bounded organelle. Predicted to be integral component of plasma membrane. Is expressed in several structures, including alimentary system; genitourinary system; nervous system; respiratory system; and sensory organ. Human ortholog(s) of this gene implicated in X-linked spinocerebellar ataxia 1. Orthologous to human ATP2B3 (ATPase plasma membrane Ca2+ transporting 3).
• Source: E. coli
• Species: Mouse
• Tag: His
• Form: 50mM Tris 300mM NaCl, pH 8.0.
• Molecular Mass: 24.5 kDa
• AA Sequence: MGSSHHHHHHSSGLVPRGSHMQFGG KPFSCSPLSTEQWLWCLFVGVGELV WGQVIATIPTSQLKCLKEAGHGPGK DEMTDEELAEGEEEIDHAERELRRG QILWFRGLNRIQTQIRVVKAFRSSL YEGLEKPESKSCIHNFMATPEFLIN DYTHNIPLIDDTDVDENEERLRAPP PPPPNQNNNAIDSGIYLTTHATKSA TSSAFSSRPGSPLHSMETSL
• Purity: ＞90%
• Storage: Store it under sterile conditions at -20 to -80 centigrade. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
• Concentration: 0.27 mg/ml

Gene Information

• Gene Name: Atp2b3 ATPase, Ca++ transporting, plasma membrane 3 [ Mus musculus (house mouse) ]
• Official Symbol: ATP2B3
• Synonyms: Pmca3; 6430519O13Rik
• Gene ID: 320707
• mRNA Refseq: NM_177236
• Protein Refseq: NP_796210
• MIM: 300014
• UniProt ID: Q0VF55