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Official Full Name butyrylcholinesterase
Background Mutant alleles at the BCHE locus are responsible for suxamethonium sensitivity. Homozygous persons sustain prolonged apnea after administration of the muscle relaxant suxamethonium in connection with surgical anesthesia. The activity of pseudocholinesterase in the serum is low and its substrate behavior is atypical. In the absence of the relaxant, the homozygote is at no known disadvantage.
Synonyms BCHE; butyrylcholinesterase; CHE1, cholinesterase 1; cholinesterase; E1; Acylcholine acylhydrolase; Choline esterase II; Pseudocholinesterase; Butyrylcholine esterase; CHE1; CHLE_HUMAN; cholinesterase 1; OTTHUMP00000212636
    • Species :
    • Chicken
    • Dog
    • Equine
    • Human
    • Mouse
    • Rat
    • Source :
    • CHO-K1
    • E.coli
    • Equine Serum
    • HEK293
    • HEK293T
    • Horse Serum
    • Human Cell
    • Human Serum
    • Mammalian Cell
    • Mammalian cells
    • Trichoplusia Ni Larval
    • Wheat Germ
    • Tag :
    • GST
    • His
    • MYC/DDK
    • Myc
    • DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human BCHE-10H Recombinant Human BCHE, His-tagged Trichoplusia Ni Larval His
    Human BCHE-134H Recombinant Human BCHE Protein, GST-tagged Wheat Germ GST
    Human BCHE-2196HCL Recombinant Human BCHE cell lysate Human Cell N/A
    Human BCHE-2468H Recombinant Human BCHE Protein, MYC/DDK-tagged HEK293 Myc/DDK
    Human BCHE-2533H Recombinant Human BCHE CHO-K1 N/A
    Human BCHE-26067TH Native Human BCHE N/A
    Human BCHE-5291H Native Human Butyrylcholinesterase Human Serum N/A
    Human BCHE-574H Recombinant Human BCHE Protein, His-tagged E.coli His
    Human BCHE-8054H Native Human Serum ButyrylcholinEsterase Human Serum N/A
    Human BCHE-901H Recombinant Human BCHE, His tagged Human Cell His
    Mouse BCHE-2286MCL Recombinant Mouse BCHE cell lysate Human Cell N/A
    Mouse Bche-355M Recombinant Mouse Bche, His-tagged Mammalian cells His
    Mouse Bche-695M Recombinant Mouse Bche Protein, MYC/DDK-tagged HEK293T MYC/DDK
    Mouse Bche-910M Recombinant Mouse Bche, His tagged Human Cell His
    Rat Bche-575R Recombinant Rat Bche Protein, His-tagged E.coli His
    Dog BCHE-354D Recombinant Dog BCHE Protein (1-141 aa), His-tagged E.coli His
    Chicken BCHE-6214C Recombinant Chicken BCHE Mammalian Cell His
    Equine BCHE-157H Native Horse Serum Butyrylcholinesterase Horse Serum N/A
    Equine BCHE-8E Native Equine Butyrylcholine esterase Equine Serum N/A
    Kit-0133 Butyrylcholinesterase Fluorometric Detection Kit N/A
    Kit-2349 Butyrylcholinesterase Activity Kit (Colorimetric) N/A

    bche involved in several pathways and played different roles in them. We selected most pathways bche participated on our site, such as Glycerophospholipid biosynthesis, Metabolism, Metabolism of lipids and lipoproteins, which may be useful for your reference. Also, other proteins which involved in the same pathway with bche were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Glycerophospholipid biosynthesis GPAT2; CDIPT; PLBD1; AWAT1; CPNE3; CPNE7; PTPMT1; ABHD4; BCHE; PLD6
    Metabolism Alb; SLC2A3; TM9SF1; PEMT; CYP2U1; CYP2F1; DECR1; PRKRA; CYP2K8; CYGB
    Metabolism of lipids and lipoproteins AKR1C2; PTGDSA; MTP; CPTP; NEU3; GLTPA; MED23; DHCR24; GPAT2; CTGF
    Metabolism of proteins MUC1; SPON1; IGFBP2; ALG14; PFDN1; TIMM8A; THSD7A; PAPPA; TMED2; LMAN2
    Neurotransmitter Clearance In The Synaptic Cleft BCHE
    Peptide hormone metabolism SLC38A8; CDX2; EXOC8; INHA; BCHE; GRP; GPR119; CPN1; MBOAT4; PCSK2

    bche has several biochemical functions, for example, acetylcholinesterase activity, beta-amyloid binding, catalytic activity. Some of the functions are cooperated with other proteins, some of the functions could acted by bche itself. We selected most functions bche had, and list some proteins which have the same functions with bche. You can find most of the proteins on our site.

    Function Related Protein
    acetylcholinesterase activity ACHE; BCHE
    beta-amyloid binding MAPK8IP2; LDLRAP1; GPRASP2; COL25A1; TSSK1B; APBB3; APBB1; APBA2; NGFR; ARMCX5-GPRASP2
    catalytic activity SYN2A; ASAH1; ACSL4B; ACSS2L; SLC3A2; AGLA; BLM; CDYL2; AOX3; AADAC
    choline binding CRP; CHKA; BCHE; SLC5A7
    cholinesterase activity CEL.1; ACHE; BCHE; CHKA; CELL
    enzyme binding PARK7; TAF10; PTPLA; KMT2E; TNKS2; PPP3CB; ATF7; GRIN1; KALRN; XRCC1
    identical protein binding CLDN7; Serpina1c; PIP4K2C; TMEM173; TRA@; GYPA; MCIN; SMAD1; CST3; UBE2G2

    bche has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with bche here. Most of them are supplied by our site. Hope this information will be useful for your research of bche.


    Schopfer, LM; Masson, P; et al. Detection of cresyl phosphate-modified butyrylcholinesterase in human plasma for chemical exposure associated with aerotoxic syndrome. ANALYTICAL BIOCHEMISTRY 461:17-26(2014).
    Schneider, JD; Marillonnet, S; et al. Oligomerization status influences subcellular deposition and glycosylation of recombinant butyrylcholinesterase in Nicotiana benthamiana. PLANT BIOTECHNOLOGY JOURNAL 12:832-839(2014).

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