Active Recombinant Human BCHE
Cat.No. : | BCHE-2533H |
Product Overview : | Recombinant human butyrylcholinesterase (BChE) produced from conditioned medium of stably-transfected CHO-K1 cells is a tetramer form associated with a proline-rich attachment domain (PRAD). Each mature polypeptide contains 574 amino acids having a predicted molecular mass of approximately 65kD, but migrates with an approximate molecular mass of 280kD in non-reduced SDS gel. |
- Specification
- Gene Information
- Related Products
Description : | Butyrylcholinesterase (BCHE, or BuChE), also known as pseudocholinesterase or plasma cholinesterase) is a non-specific cholinesterase enzyme that hydrolyses many different choline esters. In humans, it is found primarily in the liver and is encoded by the BCHE gene. |
Source : | CHO-K1 cells |
Species : | Human |
Form : | 20mM Tris-Cl (pH7.9), 20% Glycerol, 100mM NaCl, 1mM DTT and 0.5mM EDTA |
Bio-activity : | Butyrylcholinesterase is a serine hydrolase and has a potential role in in maintaining and regulating the activity of neurotransmitter acetylcholine in the central nervous system. Recombinant human BChE protein has similar pharmacokinetic and protective properties to plasma-derived BChE and is suitable for other related function assays. |
AA Sequence : | EDDIIIATKNGKVRGMNLTVFGGTV TAFLGIPYAQPPLGRLRFKKPQSLT KWSDIWNATKYANSCCQNIDQSFP GFHGSEMWNPNTDLSEDCLYLNVWI PAPKPKNATVLIWIYGGGFQTGTSS LHVYDGKFLARVERVIVVSMNYRV GALGFLALPGNPEAPGNMGLFDQQL ALQWVQKNIAAFGGNPKSVTLFGES AGAASVSLHLLSPGSHSLFTRAI LQSGSFNAPWAVTSLYEARNRTLNL AKLTGCSRENETEIIKCLRNKDPQE ILLNEAFVVPYGTPLSVNFGPTVD GDFLTDMPDILLELGQFKKTQILVG VNKDEGTAFLVYGAPGFSKDNNSII TRKEFQEGLKIFFPGVSEFGKES ILFHYTDWVDDQRPENYREALGDVV GDYNFICPALEFTKKFSEWGNNAFF YYFEHRSSKLPWPEWMGVMHGYEI EFVFGLPLERRDNYTKAEEILSRSI VKRWANFAKYGNPNETQNNSTSWPV FKSTEQKYLTLNTESTRIMTKLR AQQCRFWTSFFPKVLEMTGNIDEAE WEWKAGFHRWNNYMMDWKNQFNDYT SKKESCVGL |
Purity : | ≥90%, as determined by SDS-PAGE |
Usage : | FOR RESEARCH ONLY |
Storage : | The protein sample can be stored under sterile conditions at 2- 8 centigrade for one month or at -70 centigrade for three months without detectable loss of activity. Avoid repeated freeze-thaw cycles. |
Gene Name : | BCHE butyrylcholinesterase [ Homo sapiens ] |
Official Symbol : | BCHE |
Synonyms : | E1; CHE1; CHE2; cholinesterase; acylcholine acylhydrolase; butyrylcholine esterase; choline esterase II; cholinesterase (serum) 2; cholinesterase 1; pseudocholinesterase |
Gene ID : | 590 |
mRNA Refseq : | NM_000055 |
Protein Refseq : | NP_000046 |
MIM : | 177400 |
UniProt ID : | P06276 |
Chromosome Location : | 3q26.1-q26.2 |
Pathway : | Glycerophospholipid biosynthesis, organism-specific biosystem; Metabolism, organism-specific biosystem; Metabolism of proteins, organism-specific biosystem |
Function : | acetylcholinesterase activity; beta-amyloid binding; catalytic activity |
Products Types
◆ Recombinant Protein | ||
BCHE-354D | Recombinant Dog BCHE Protein (1-141 aa), His-tagged | +Inquiry |
BCHE-303H | Recombinant Human BCHE Protein, His-tagged | +Inquiry |
BCHE-435H | Recombinant Human BCHE Protein, His (Fc)-Avi-tagged | +Inquiry |
BCHE-574H | Recombinant Human BCHE Protein, His-tagged | +Inquiry |
Bche-695M | Recombinant Mouse Bche Protein, MYC/DDK-tagged | +Inquiry |
◆ Native Protein | ||
BCHE-8054H | Native Human Serum ButyrylcholinEsterase | +Inquiry |
BCHE-8E | Active Native Equine Butyrylcholine esterase | +Inquiry |
BCHE-157H | Active Native Horse Serum Butyrylcholinesterase | +Inquiry |
◆ Lysates | ||
BCHE-2196HCL | Recombinant Human BCHE cell lysate | +Inquiry |
BCHE-2286MCL | Recombinant Mouse BCHE cell lysate | +Inquiry |
◆ Assay kits | ||
Kit-2349 | Butyrylcholinesterase Activity Kit (Colorimetric) | +Inquiry |
Kit-0133 | Butyrylcholinesterase Fluorometric Detection Kit | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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