|Official Full Name||bone gamma-carboxyglutamate (gla) protein|
|Background||Osteocalcin, also known as bone gamma-carboxyglutamic acid-containing protein (BGLAP), is a noncollagenous protein found in bone and dentin. In humans, the osteocalcin is encoded by the BGLAP gene.|
|Synonyms||BGLAP; bone gamma-carboxyglutamate (gla) protein; OC; BGP; osteocalcin; bone Gla protein; OTTHUMP00000016586; gamma-carboxyglutamic acid-containing protein; bone gamma-carboxyglutamate (gla) protein (osteocalcin)|
|Species||Cat.#||Product name||Source (Host)||Tag||Protein Length||Price|
BGLAP involved in several pathways and played different roles in them. We selected most pathways BGLAP participated on our site, such as FGF signaling pathway, Glucocorticoid receptor regulatory network, Interleukin-11 Signaling Pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with BGLAP were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
|Pathway Name||Pathway Related Protein|
|FGF signaling pathway||PAK4; FGFRL1B; FGF24; TA; SPRY2; SP8B; EGR2A; SP8A; SOX32; JUNBA|
|Glucocorticoid receptor regulatory network||SMARCA4; POU2F1; SMARCC2; BGLAP; CSN2; KRT14; SMARCD1; KRT5; EGR1; NR1I3|
|Interleukin-11 Signaling Pathway||IL11; BGLAP|
|Notch-mediated HES/HEY network||HEY1; CTBP1; MYOD1; YY1; RCAN1; GATA1; GATA6; ASCL1; HES6; BGLAP|
|Regulation of retinoblastoma protein||GSC; CKM; ELF1; MYOD1; CBX4; BGLAP; ATF7; SMARCB1; BRD2; AATF|
|Validated transcriptional targets of AP1 family members Fra1 and Fra2||CXorf15; USF2; IVL; MGP; BGLAP|
BGLAP has several biochemical functions, for example, calcium ion binding, hydroxyapatite binding, structural constituent of bone. Some of the functions are cooperated with other proteins, some of the functions could acted by BGLAP itself. We selected most functions BGLAP had, and list some proteins which have the same functions with BGLAP. You can find most of the proteins on our site.
|calcium ion binding||EYS; SLC25A25A; SYT17; SVEP1; PCDH2G1; DSG2.1; CHP; CACNA1SA; THBS4A; MBL2|
|hydroxyapatite binding||BGLAP; AMELX; HTN1; PTPLA; BGLAP2; STATH|
|structural constituent of bone||BGLAP; BGLAP2; BGLAP-RS1; MGP|
|structural molecule activity||EIF3A; KRT97; SEMG1; CLTCB; CLDNE; KRT24; IFLTD1; KRT23; MAPK8IP2; COPE|
BGLAP has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with BGLAP here. Most of them are supplied by our site. Hope this information will be useful for your research of BGLAP.