Native Bovine BGLAP
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Cat.No. : | BGLAP-8519B Optional Service: Optional requirements on this protein |
Product Overview : | Native Bovine BGLAP is purified from Osteocalcin is prepared from bovine bone generally as described by Price et al. This involves demineralization in EDTA, size exclusion and ion exchange chromatography. |
Description : | Osteocalcin, also known as Bone-Gla-Protein (BGP), is a single chain (Mr=5800) vitamin K dependent protein produced by osteoblasts and found in high concentrations in bone. Post-translational modification by a vitamin K dependent carboxylase produces three g-carboxyglutamic acid residues at positions 17, 21 and 24. The mature protein contains 49 amino acids and a single intrachain disulfide bond joining Cys23 to Cys29. The secondary structure is highly calcium dependent and contains 14% α-helix, 20% β-sheet and 67% random form in the presence of calcium, and 1% α-helix, 20% β-sheet and 79% random form in the absence of calcium. |
Source : | Bovine |
Species : | Bovine |
Form : | 50% glycerol/H2O (v/v) |
Molecular Mass : | 5,800 |
Purity : | >95% by SDS-PAGE |
Storage : | -80℃ aqueous; -20℃ glycerol |
Gene Name : | BGLAP bone gamma-carboxyglutamate (gla) protein [ Bos taurus ] |
Official Symbol : | BGLAP |
Synonyms : | BGLAP; BOS_2768; BGP; bone Gla protein; gamma-carboxyglutamic acid-containing protein; osteocalcin |
Gene ID : | 281646 |
mRNA Refseq : | NM_174249.2 |
Protein Refseq : | NP_776674.1 |
UniProt ID : | P02820 |
Function : | calcium ion binding |
◆ Recombinant Protein
BGLAP-634R | Recombinant Rat BGLAP Protein, His (Fc)-Avi-tagged | +Inquiry |
Bglap-1262M | Recombinant Mouse Bglap Protein, His-tagged | +Inquiry |
Bglap-707M | Recombinant Mouse Bglap Protein, MYC/DDK-tagged | +Inquiry |
BGLAP-2543H | Recombinant Human BGLAP Protein, His (Fc)-Avi-tagged | +Inquiry |
Bglap-1143R | Recombinant Rat Bglap Protein, GST-tagged | +Inquiry |
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◆ Native Protein
BGLAP-60H | Native Human BGLAP protein | +Inquiry |
BGLAP-57H | Native Human Osteocalcin | +Inquiry |
BGLAP-286B | Native Bovine Osteocalcin | +Inquiry |
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◆ Lysates
BGLAP-8460HCL | Recombinant Human BGLAP 293 Cell Lysate | +Inquiry |
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