BPI
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Official Full Name
bactericidal/permeability-increasing protein
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Overview
This gene encodes a lipopolysaccharide binding protein. It is associated with human neutrophil granules and has bactericidal activity on gram-negative organisms. -
Synonyms
BPI; bactericidal/permeability-increasing protein; bactericidal permeability-increasing protein; BPI fold containing family D; member 1; BPIFD1; CAP 57; OTTHUMP00000030962; OTTHUMP00000030963; recombinant BPI holoprotein, rBPI; BPI fold containing family D, member 1; rBPI;
- Recombinant Proteins
- Cell & Tissue Lysates
- Native Proteins
- Protein Pre-coupled Magnetic Beads
- Cattle
- Human
- Mouse
- Rabbit
- Rat
- E.coli
- HEK293
- HEK293T
- Human Cell
- Human Neutrophil
- Human Whole Blood
- Mammalian Cell
- Mammalian cells
- C
- His
- Fc Chimera
- His (Fc)
- Avi
- His|GST
- His|T7
- Myc
- DDK
- Myc|DDK
- N/A
- N
- GST
- Involved Pathway
- Protein Function
- Interacting Protein
- BPI Related Articles
BPI involved in several pathways and played different roles in them. We selected most pathways BPI participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with BPI were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
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BPI has several biochemical functions, for example, lipopolysaccharide binding. Some of the functions are cooperated with other proteins, some of the functions could acted by BPI itself. We selected most functions BPI had, and list some proteins which have the same functions with BPI. You can find most of the proteins on our site.
Function | Related Protein |
---|---|
lipopolysaccharide binding | TLR4;BPI;TREM2;KIAA0644;CD14;BPIFA2;P2RX7;TRIL;SPON2 |
BPI has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with BPI here. Most of them are supplied by our site. Hope this information will be useful for your research of BPI.
- Q&As
- Reviews
Q&As (5)
Ask a questionTechniques such as X-ray crystallography, surface plasmon resonance, and functional assays are commonly used to study BPI. These approaches provide insights into its structure, interactions, and immune modulatory activities.
BPI regulates the inflammatory response by interacting with immune cells and modulating signaling pathways. Its binding to lipopolysaccharides and subsequent interactions influence immune cell activation and cytokine production.
BPI plays a crucial role in the host response to sepsis and infectious diseases. Understanding its contribution may unveil therapeutic strategies for modulating BPI activity to enhance host defense mechanisms.
BPI influences neutrophil functions by modulating their activation and bactericidal activities. Its role in coordinating immune responses against extracellular bacteria is crucial for efficient host defense.
BPI interacts with the complement system, influencing immune response coordination. Its regulatory role in complement activation contributes to the orchestration of the immune response against pathogens.
Customer Reviews (3)
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