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BPI

  • Official Full Name

    bactericidal/permeability-increasing protein

  • Overview

    This gene encodes a lipopolysaccharide binding protein. It is associated with human neutrophil granules and has bactericidal activity on gram-negative organisms.
  • Synonyms

    BPI; bactericidal/permeability-increasing protein; bactericidal permeability-increasing protein; BPI fold containing family D; member 1; BPIFD1; CAP 57; OTTHUMP00000030962; OTTHUMP00000030963; recombinant BPI holoprotein, rBPI; BPI fold containing family D, member 1; rBPI;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Native Proteins
  • Protein Pre-coupled Magnetic Beads
  • Cattle
  • Human
  • Mouse
  • Rabbit
  • Rat
  • E.coli
  • HEK293
  • HEK293T
  • Human Cell
  • Human Neutrophil
  • Human Whole Blood
  • Mammalian Cell
  • Mammalian cells
  • C
  • His
  • Fc Chimera
  • His (Fc)
  • Avi
  • His|GST
  • His|T7
  • Myc
  • DDK
  • Myc|DDK
  • N/A
  • N
  • GST
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human BPI-175H Active Recombinant Human BPI, Fc Chimera HEK293 Fc Chimera
Human BPI-7374H Recombinant Human BPI protein, His-tagged HEK293 His Met1-Lys487
Human BPI-5847H Recombinant Human BPI protein, His & GST-tagged E.coli His/GST Glu140~Thr250 (Accession # P17213)
Human BPI-1493HCL Recombinant Human BPI cell lysate Human Cell N/A
Human BPI-182H Native Human Bacterial/Permeability-Increasing Protein Human Whole Blood N/A
Human BPI-0785H Recombinant Human BPI Protein (Glu140-Thr250), N-GST tagged E.coli N-GST Glu140-Thr250
Human BPI-2789H Recombinant Human BPI Protein, MYC/DDK-tagged HEK293 Myc/DDK
Human BPI-0833H Recombinant Human BPI Protein (Val32-Lys487), C-His tagged Mammalian cells C-His Val32-Lys487
Human BPI-2070H Recombinant Human BPI Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human BPI-72H Native Human Bacterial/Permeability-Increasing Protein Human Neutrophil N/A
Mouse BPI-2461M Recombinant Mouse BPI Protein Mammalian Cell His
Mouse Bpi-5848M Recombinant Mouse Bpi protein, His & T7-tagged E.coli His/T7 Asn320~Pro457 (Accession# Q67E05)
Mouse Bpi-1885M Recombinant Mouse Bpi Protein, Myc/DDK-tagged HEK293T Myc/DDK
Mouse BPI-1072M Recombinant Mouse BPI Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse BPI-1072M-B Recombinant Mouse BPI Protein Pre-coupled Magnetic Beads HEK293
Rat Bpi-5849R Recombinant Rat Bpi protein, His-tagged E.coli His Asn320~Pro452 (Accession # Q6AXU0)
Rat BPI-1005R Recombinant Rat BPI Protein Mammalian Cell His
Rat BPI-663R Recombinant Rat BPI Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat BPI-663R-B Recombinant Rat BPI Protein Pre-coupled Magnetic Beads HEK293
Rabbit BPI-327R Recombinant Rabbit BPI Protein, His-tagged E.coli N-His Ser315-Leu451
Cattle BPI-177C Recombinant Cattle BPI Protein, His-tagged E.coli N-His Arg36-Ala93+HHHHHH
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • BPI Related Articles

BPI involved in several pathways and played different roles in them. We selected most pathways BPI participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with BPI were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein

BPI has several biochemical functions, for example, lipopolysaccharide binding. Some of the functions are cooperated with other proteins, some of the functions could acted by BPI itself. We selected most functions BPI had, and list some proteins which have the same functions with BPI. You can find most of the proteins on our site.

Function Related Protein
lipopolysaccharide bindingTLR4;BPI;TREM2;KIAA0644;CD14;BPIFA2;P2RX7;TRIL;SPON2

BPI has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with BPI here. Most of them are supplied by our site. Hope this information will be useful for your research of BPI.

Yamauchi, T; Matsushita, S; et al. Major cleavage-dependent epitopes for linear IgA bullous dermatosis are formed at the boundary between the non-collagenous 16A and collagenous 15 domains of BP180. JOURNAL OF DERMATOLOGICAL SCIENCE 76:25-33(2014).
Martin-Broto, J; Cleeland, CS; et al. Effects of denosumab on pain and analgesic use in giant cell tumor of bone: Interim results from a phase II study. ACTA ONCOLOGICA 53:1173-1179(2014).
  • Q&As
  • Reviews

Q&As (5)

Ask a question
What experimental techniques are commonly used to study BPI, including its structure, interactions, and functional activities in immune responses? 03/24/2022

Techniques such as X-ray crystallography, surface plasmon resonance, and functional assays are commonly used to study BPI. These approaches provide insights into its structure, interactions, and immune modulatory activities.

How does BPI participate in the regulation of the inflammatory response, and what molecular mechanisms underlie its interaction with immune cells? 08/05/2021

BPI regulates the inflammatory response by interacting with immune cells and modulating signaling pathways. Its binding to lipopolysaccharides and subsequent interactions influence immune cell activation and cytokine production.

In the context of sepsis and other infectious diseases, how does BPI contribute to the host's response, and are there therapeutic implications for modulating BPI activity? 02/09/2020

BPI plays a crucial role in the host response to sepsis and infectious diseases. Understanding its contribution may unveil therapeutic strategies for modulating BPI activity to enhance host defense mechanisms.

How does BPI influence neutrophil functions, and what role does it play in the coordination of immune responses against extracellular bacteria? 07/06/2019

BPI influences neutrophil functions by modulating their activation and bactericidal activities. Its role in coordinating immune responses against extracellular bacteria is crucial for efficient host defense.

How does BPI participate in the regulation of the complement system, and what implications does this have for immune response coordination? 10/27/2018

BPI interacts with the complement system, influencing immune response coordination. Its regulatory role in complement activation contributes to the orchestration of the immune response against pathogens.

Customer Reviews (3)

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Reviews
01/25/2021

    A product of exceptional quality, paired with customer service that is both attentive and efficient.

    05/14/2020

      Timely delivery made the experience even better.

      10/02/2018

        Great product quality, friendly customer service, and quick delivery

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