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Official Full Name calcium channel, voltage-dependent, gamma subunit 3
Background The protein encoded by this gene is a type I transmembrane AMPA receptor regulatory protein (TARP). TARPs regulate both trafficking and channel gating of the AMPA receptors. This gene is part of a functionally diverse eight-member protein subfamily of the PMP-22/EMP/MP20 family. This gene is a susceptibility locus for childhood absence epilepsy.
Synonyms CACNG3; calcium channel, voltage-dependent, gamma subunit 3; voltage-dependent calcium channel gamma-3 subunit; CACNG 3; Cacng2; Calcium channel voltage dependent gamma subunit 3; Neuronal voltage gated calcium channel gamma 3 subunit; Voltage dependent calcium channel gamma 3 subunit; Voltage gated calcium channel gamma subunit; TARP gamma-3; voltage-gated calcium channel gamma subunit; transmembrane AMPAR regulatory protein gamma-3; neuronal voltage-gated calcium channel gamma-3 subunit
    • Species :
    • Chicken
    • Cynomolgus Monkey
    • Human
    • Mouse
    • Rat
    • Rhesus Macaque
    • Source :
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human CACNG3-0276H Recombinant Human CACNG3 Protein, GST-Tagged Wheat Germ GST
    Human CACNG3-270HCL Recombinant Human CACNG3 cell lysate N/A
    Mouse CACNG3-2625M Recombinant Mouse CACNG3 Protein Mammalian Cell His
    Rat CACNG3-1072R Recombinant Rat CACNG3 Protein Mammalian Cell His
    Cynomolgus Monkey CACNG3-355C Recombinant Cynomolgus CACNG3 Protein, His-tagged Mammalian Cell His
    Rhesus Macaque CACNG3-604R Recombinant Rhesus monkey CACNG3 Protein, His-tagged Mammalian Cell His
    Chicken CACNG3-6227C Recombinant Chicken CACNG3 Mammalian Cell His

    cacng3 involved in several pathways and played different roles in them. We selected most pathways cacng3 participated on our site, such as Adrenergic signaling in cardiomyocytes, Arrhythmogenic right ventricular cardiomyopathy, Arrhythmogenic right ventricular cardiomyopathy (ARVC), which may be useful for your reference. Also, other proteins which involved in the same pathway with cacng3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Adrenergic signaling in cardiomyocytes PPP2R5B; PIK3CB; CAMK2G1; ADCY3; KCNE1; PPP2R2A; ATP1A3B; PLCB2; MAPK12; TPM1
    Arrhythmogenic right ventricular cardiomyopathy CTNNA1; DSG2; DES; CACNG2; JUP; DSC2; CTNNA2; DAG1; CDH2; CACNG3
    Arrhythmogenic right ventricular cardiomyopathy (ARVC) ITGB7; CACNG1; GJA1; EMD; CDH2; ACTN3; DAG1; ITGA6; ITGA8; ITGA9
    Cardiac muscle contraction SLC8A1; ATP1A4; TNNC1B; ATP1B1B; CACNA2D2; ATP1A1A.1; UQCR10; ACTC1; UQCR11; CACNA1DA
    Developmental Biology CNTN6; CLTA; SPAG9; EFNB2A; RHOGA; DPYSL5B; EFNB2; RGMB; RASGRP4; SCN8A
    Dilated cardiomyopathy EMD; ITGA6; TNNC1; ITGB6; CACNG7; CACNA2D2; ITGA10; PRKACG; ACTB; CACNG4
    Glutamate Binding, Activation of AMPA Receptors and Synaptic Plasticity HAND2; CACNG2; CACNG3; PICK1; GRIP1; MYO6; NSFB; NSFA; AKAP5
    Hypertrophic cardiomyopathy (HCM) PRKAG1; CACNG6; ITGB5; CACNA2D4; CACNG4; ITGA1; PRKAB1; ITGB6; ITGA6; SGCD

    cacng3 has several biochemical functions, for example, channel regulator activity, voltage-gated calcium channel activity. Some of the functions are cooperated with other proteins, some of the functions could acted by cacng3 itself. We selected most functions cacng3 had, and list some proteins which have the same functions with cacng3. You can find most of the proteins on our site.

    Function Related Protein
    channel regulator activity CACNG3; SLC9A3R2; CACNG2B; CACNG2A; CACNG4; CNIH3; CACNG8; CACNG8A; CACNG7A; SNF8
    voltage-gated calcium channel activity ITGAV; ATP6V0CB; CACNB4A; TPC3; CACNB4B; TPCN2; CATSPER1; CACNG2; CALHM1; CACNB3A

    cacng3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with cacng3 here. Most of them are supplied by our site. Hope this information will be useful for your research of cacng3.

    Endoh, T; et al. Characterization of modulatory effects of postsynaptic metabotropic glutamate receptors on calcium currents in rat nucleus tractus solitarius. BRAIN RESEARCH 1024:212-224(2004).
    Yamada, E; Endoh, T; et al. Angiotensin II-induced inhibition of calcium currents via G(q/11)-protein involving protein kinase C in hamster submandibular ganglion neurons. NEUROSCIENCE RESEARCH 43:179-189(2002).

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