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Recombinant Human CACNG3 Protein, GST-Tagged

Cat.No. : CACNG3-0276H
Product Overview : Human CACNG3 partial ORF (NP_006530, 199 a.a. - 297 a.a.) recombinant protein with GST-tag at N-terminal.
  • Specification
  • Gene Information
  • Related Products
Description : The protein encoded by this gene is a type I transmembrane AMPA receptor regulatory protein (TARP). TARPs regulate both trafficking and channel gating of the AMPA receptors. This gene is part of a functionally diverse eight-member protein subfamily of the PMP-22/EMP/MP20 family. This gene is a susceptibility locus for childhood absence epilepsy. [provided by RefSeq, Dec 2010]
Source : Wheat Germ
Species : Human
Tag : GST
Molecular Mass : 36.63 kDa
AA Sequence : IYIEKHQQLRAKSHSEFLKKSTFAR LPPYRYRFRRRSSSRSTEPRSRDLS PISKGFHTIPSTDISMFTLSRDPSK ITMGTLLNSDRDHAFLQFHNSTPK
Applications : Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
Notes : Best use within three months from the date of receipt of this protein.
Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Storage Buffer : 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Gene Name : CACNG3 calcium channel, voltage-dependent, gamma subunit 3 [ Homo sapiens ]
Official Symbol : CACNG3
Synonyms : CACNG3; calcium channel, voltage-dependent, gamma subunit 3; voltage-dependent calcium channel gamma-3 subunit; TARP gamma-3; voltage-gated calcium channel gamma subunit; transmembrane AMPAR regulatory protein gamma-3; neuronal voltage-gated calcium channel gamma-3 subunit;
Gene ID : 10368
mRNA Refseq : NM_006539
Protein Refseq : NP_006530
MIM : 606403
UniProt ID : O60359

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (7)

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Have any post-translational modifications been identified on CACNG3? 01/20/2022

Techniques like mass spectrometry might reveal specific post-translational modifications on CACNG3.

How do genetic mutations in the CACNG3 gene influence its regulatory role? 03/13/2021

Genetic mutations in the CACNG3 gene can alter its regulatory function, impacting the dynamics and behavior of related calcium channels.

Are there specific proteins known to interact directly with CACNG3? 08/23/2020

CACNG3 primarily interacts with the alpha-1 subunit of calcium channels and may have associations with other channel proteins.

Which human tissues or cells predominantly express CACNG3? 06/05/2020

CACNG3 is mainly expressed in the brain, especially within neural tissues.

Are there any diseases or disorders directly linked to CACNG3 dysfunction? 03/14/2020

Dysfunctions or mutations in CACNG3 are implicated in certain neurological conditions, although deeper research is essential for concrete associations.

How does CACNG3 modulate the function of associated calcium channels? 06/29/2018

By binding to calcium channels, CACNG3 can influence the channel's gating dynamics, its localization, and the properties of calcium ion permeation.

What is the main biological role of CACNG3 in relation to calcium channels? 01/19/2018

CACNG3 serves as an auxiliary subunit, contributing to the modulation of the trafficking, activity, and surface expression of voltage-gated calcium channels.

Customer Reviews (3)

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Reviews
07/06/2022

    Precision in protein characterization, unmatched quality.

    05/17/2021

      Efficient protein quantification, a time and resource saver.

      01/28/2021

        Top-tier protein sequencing, a research game-changer.

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