Recombinant Human CACNG3 Protein, GST-Tagged
Cat.No. : | CACNG3-0276H |
Product Overview : | Human CACNG3 partial ORF (NP_006530, 199 a.a. - 297 a.a.) recombinant protein with GST-tag at N-terminal. |
- Specification
- Gene Information
- Related Products
Description : | The protein encoded by this gene is a type I transmembrane AMPA receptor regulatory protein (TARP). TARPs regulate both trafficking and channel gating of the AMPA receptors. This gene is part of a functionally diverse eight-member protein subfamily of the PMP-22/EMP/MP20 family. This gene is a susceptibility locus for childhood absence epilepsy. [provided by RefSeq, Dec 2010] |
Source : | Wheat Germ |
Species : | Human |
Tag : | GST |
Molecular Mass : | 36.63 kDa |
AA Sequence : | IYIEKHQQLRAKSHSEFLKKSTFAR LPPYRYRFRRRSSSRSTEPRSRDLS PISKGFHTIPSTDISMFTLSRDPSK ITMGTLLNSDRDHAFLQFHNSTPK |
Applications : | Enzyme-linked Immunoabsorbent Assay Western Blot (Recombinant protein) Antibody Production Protein Array |
Notes : | Best use within three months from the date of receipt of this protein. |
Storage : | Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. |
Storage Buffer : | 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
Gene Name : | CACNG3 calcium channel, voltage-dependent, gamma subunit 3 [ Homo sapiens ] |
Official Symbol : | CACNG3 |
Synonyms : | CACNG3; calcium channel, voltage-dependent, gamma subunit 3; voltage-dependent calcium channel gamma-3 subunit; TARP gamma-3; voltage-gated calcium channel gamma subunit; transmembrane AMPAR regulatory protein gamma-3; neuronal voltage-gated calcium channel gamma-3 subunit; |
Gene ID : | 10368 |
mRNA Refseq : | NM_006539 |
Protein Refseq : | NP_006530 |
MIM : | 606403 |
UniProt ID : | O60359 |
Products Types
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◆ Lysates | ||
CACNG3-270HCL | Recombinant Human CACNG3 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (7)
Ask a questionTechniques like mass spectrometry might reveal specific post-translational modifications on CACNG3.
Genetic mutations in the CACNG3 gene can alter its regulatory function, impacting the dynamics and behavior of related calcium channels.
CACNG3 primarily interacts with the alpha-1 subunit of calcium channels and may have associations with other channel proteins.
CACNG3 is mainly expressed in the brain, especially within neural tissues.
Dysfunctions or mutations in CACNG3 are implicated in certain neurological conditions, although deeper research is essential for concrete associations.
By binding to calcium channels, CACNG3 can influence the channel's gating dynamics, its localization, and the properties of calcium ion permeation.
CACNG3 serves as an auxiliary subunit, contributing to the modulation of the trafficking, activity, and surface expression of voltage-gated calcium channels.
Customer Reviews (3)
Write a reviewPrecision in protein characterization, unmatched quality.
Efficient protein quantification, a time and resource saver.
Top-tier protein sequencing, a research game-changer.
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