CALML5

  • Official Full Name

    Calmodulin-like 5
  • Overview

    This gene encodes a novel calcium binding protein expressed in the epidermis and related to the calmodulin family of calcium binding proteins. Functional studies with recombinant protein demonstrate it does bind calcium and undergoes a conformational change when it does so. Abundant expression is detected only in reconstructed epidermis and is restricted to differentiating keratinocytes. In addition, it can associate with transglutaminase 3, shown to be a key enzyme in the terminal differentiation of keratinocytes.
  • Synonyms

    CALML5;Calmodulin-like 5

Recombinant Proteins

  • Human
  • Rhesus macaque
  • E.coli
  • Mammalian Cells
  • HEK293
  • In Vitro Cell Free System
  • GST
  • His
  • Non
  • Avi
  • Fc
  • SUMO
Cat.# Product name Source (Host) Species Tag Protein Length Price
CALML5-10673H Recombinant Human CALML5 protein, GST-tagged E.coli Human GST
CALML5-3241H Recombinant Human CALML5 protein, His-tagged E.coli Human His 1-120 aa
CALML5-369H Recombinant Human CALML5 Protein, His-tagged E.coli Human His Me1~Glu146
CALML5-3928H Recombinant Human CALML5 protein(Met1-Glu146), His&GST-tagged E.coli Human GST&His 1-146 a.a.
CALML5-609R Recombinant Rhesus monkey CALML5 Protein, His-tagged Mammalian Cells Rhesus macaque His
CALML5-7886HCL Recombinant Human CALML5 293 Cell Lysate HEK293 Human Non
CALML5-3066HF Recombinant Full Length Human CALML5 Protein, GST-tagged In Vitro Cell Free System Human GST Full L. 146 amino acids
CALML5-437R Recombinant Rhesus Macaque CALML5 Protein, His (Fc)-Avi-tagged HEK293 Rhesus macaque Avi&Fc&His
CALML5-437R-B Recombinant Rhesus Macaque CALML5 Protein Pre-coupled Magnetic Beads HEK293 Rhesus macaque
CALML5-4984H Recombinant Human CALML5 protein, His-SUMO-tagged E.coli Human His&SUMO 2-146aa
CALML5-7436H Recombinant Human CALML5 protein, GST-tagged E.coli Human GST

    Involved Pathway

    CALML5 involved in several pathways and played different roles in them. We selected most pathways CALML5 participated on our site, such as Ras signaling pathway,Rap signaling pathway,Calcium signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with CALML5 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    GnRH signaling pathway CALM2,CAMK2G1,CALM2A,MAP2K4B,MAPK8A,MAP3K1,LHB,KRAS,PRKACBA,PRKACAA
    Inflammatory mediator regulation of TRP channels CYP2C37,PRKCB,TRPV2,PLCB1,IL1B,GNAS,ACCN4,PLCB4,CALM4,PTGER4
    Phototransduction CALM1,RHO,GRK7B,RCVRNA,GRK1,RCV1,GUCA1C,SLC24A1,RGS9,CNGA1
    Oocyte meiosis PRKACAB,SGOL1,PPP1R2P9,INS1,PPP2R5CB,CDC25C,CAMK2G1,SPDYB,PTTG2,PPP1CB
    Melanogenesis CALM3A,PRKCB,GNAQ,FZD7B,CAMK2D1,DVL3A,GNAO1A,CREB3L3,CREB3L1,GNAI2A
    Ras signaling pathway RASAL3,NFKB1,PAK3,RIN1,PLA2G10,FGFR4,BCL2L1,GRIN2A,PAK1,CALML3
    Phosphatidylinositol signaling system CALM1A,PLCD1,PRKCB,TMEM55A,CALML3,PI4K2A,INPP4B,MTMR7,INPP5E,PIK3CA
    Vascular smooth muscle contraction PPP1R14AB,PRKCG,CALM2A,CACNA1C,ROCK2A,PLA2G5,MAPK1,KCNMB3,ARAF,MAP2K1
    Olfactory transduction GNG7,ARRB1,OLFR494,OR10A5,OR8A1,OLFR498,OLFR688,CALM2,OR6Q1,CALM3

    Protein Function

    CALML5 has several biochemical functions, for example, calcium ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CALML5 itself. We selected most functions CALML5 had, and list some proteins which have the same functions with CALML5. You can find most of the proteins on our site.

    Function Related Protein
    calcium ion binding CAMKK2,PCDH2AA15,PCDH2G13,NKD2A,BGLAP2,EHD2,HSPA5,EHD1,EHD1B,CRB2

    Interacting Protein

    CALML5 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CALML5 here. Most of them are supplied by our site. Hope this information will be useful for your research of CALML5.

    USP1;YWHAQ;PPP4C;USF2;MAGED1;CD81;K3;Smarcc1;STK4;LRRK2;SLX4;GABARAPL1

    Resources

    References

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