CALR3
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Official Full Name
calreticulin 3 -
Overview
The protein encoded by this gene belongs to the calreticulin family, members of which are calcium-binding chaperones;localized mainly in the endoplasmic reticulum. This protein is also localized to the endoplasmic reticulum lumen,;however, its capacity for calcium-binding may be absent or much lower than other family members. This gene is;specifically expressed in the testis, and may be required for sperm fertility. Mutation in this gene has been;associated with familial hypertrophic cardiomyopathy. -
Synonyms
CALR3;calreticulin 3;calreticulin-3;calsperin;cancer/testis antigen 93;CRT2;CT93;FLJ25355;MGC26577;CALR 3;Calreticulin 2;Calreticulin2;Calreticulin3;calreticulin-2;CMH19
Recombinant Proteins
- Human
- Mouse
- E.coli
- Wheat Germ
- HEK293
- In Vitro Cell Free System
- His
- GST
- Non
- DDK
- Myc
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| CALR3-10675H | Recombinant Human CALR3, His-tagged | E.coli | Human | His | 1-384a.a. | |
| CALR3-0314H | Recombinant Human CALR3 Protein, GST-Tagged | Wheat Germ | Human | GST |
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| CALR3-271H | Recombinant Human CALR3 protein | E.coli | Human | Non | Thr20-Leu384 |
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| CALR3-476H | Recombinant Human calreticulin 3, His-tagged | E.coli | Human | His | 20-384 a.a. |
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| CALR3-5077H | Recombinant Human CALR3, His-tagged | E.coli | Human | His |
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| CALR3-7884HCL | Recombinant Human CALR3 293 Cell Lysate | HEK293 | Human | Non |
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| CALR3-1907H | Recombinant Human CALR3 Protein, Myc/DDK-tagged, C13 and N15-labeled | HEK293 | Human | DDK&Myc |
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| Calr3-1941M | Recombinant Mouse Calr3 Protein, Myc/DDK-tagged | HEK293 | Mouse | DDK&Myc |
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| CALR3-3079HF | Recombinant Full Length Human CALR3 Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 21-384 amino acids |
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Involved Pathway
CALR3 involved in several pathways and played different roles in them. We selected most pathways CALR3 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with CALR3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
CALR3 has several biochemical functions, for example, calcium ion binding,carbohydrate binding,protein binding involved in protein folding. Some of the functions are cooperated with other proteins, some of the functions could acted by CALR3 itself. We selected most functions CALR3 had, and list some proteins which have the same functions with CALR3. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| calcium ion binding | LCP1,EMR2,Npnt,PVALB1,PCDHA2,NCS1A,RHOT1B,NKD2,TNNC1A,SPOCK1 |
| unfolded protein binding | CCT5,HSPE1,CANX,DNAJA1,CLN3,SYVN1,HSPA9,DNAJB2,CHAF1A,AFG3L2 |
| protein binding involved in protein folding | RIC3,PDCL3,DNAJB8,CALR,CD74,HSPA1B,HSPA1A,PFDN2,CLGN,PFDN1 |
| carbohydrate binding | ITLN1,GALNT10,SORD,ILLR4,AIM1,ATRNL1,SIGLEC11,REG1B,FCN3,CLEC4F |
Interacting Protein
CALR3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CALR3 here. Most of them are supplied by our site. Hope this information will be useful for your research of CALR3.
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References
- Prashad, K; Mehra, S; et al. Dynamics of unfolded protein response in recombinant CHO cells. CYTOTECHNOLOGY 67:237-254(2015).
- Vannucchi, MG; Traini, C; et al. Telocytes subtypes in human urinary bladder. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE 18:2000-2008(2014).
