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Recombinant Human CALR3, His-tagged

Cat.No. : CALR3-5077H
Product Overview : Recombinant human CALR3 protein was expressed in E.coli.
  • Specification
  • Gene Information
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Description : Calreticulin 3, also known as CALR3, is a member of the calreticulin (CRT) family. It is calcium-binding chaperones that are localized to the endoplasmic reticulum or sarcoplasmic reticulum in eukaryotes. CALR3 assists in the calreticulin/calnexin cycle, where it is involved in protein-folding, oligomeric assembly and quality control in the ER. With specific expression in testis, CALR3 has been implicated as a cancer-testis antigen due to its frequent expression in various cancers.
Source : E. coli
Species : Human
Tag : His
Form : Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 0.4M Urea, 10% glycerol
Molecular Mass : 43 kDa (366aa)
AA Sequence : MTVYFQEEFL DGEHWRNRWL QSTNDSRFGH FRLSSGKFYG HKEKDKGLQT TQNGRFYAIS ARFKPFSNKG KTLVIQYTVK HEQKMDCGGG YIKVFPADID QKNLNGKSQY YIMFGPDICG FDIKKVHVIL HFKNKYHENK KLIRCKVDGF THLYTLILRP DLSYDVKIDG QSIESGSIEY DWNLTSLKKE TSPAESKDWE QTKDNKAQDW EKHFLDASTS KQSDWNGDLD GDWPAPMLQK PPYQDGLKPE GIHKDVWLHR KMKNTDYLTQ YDLSEFENIG AIGLELWQVR SGTIFDNFLI TDDEEYADNF GKATWGETKG PEREMDAIQA KEEMKKAREE EEEELLSGKI NRHEHYFNQF HRRNEL
Purity : >90% by SDS - PAGE
Applications : SDS-PAGE
Storage : Can be stored at +4centigrade short term (1-2 weeks). For long term storage, aliquot and store at -20centigrade or -70centigrade. Avoid repeated freezing and thawing cycles.
Concentration : 1 mg/ml (determined by Bradford assay)
Gene Name : CALR3 calreticulin 3 [ Homo sapiens ]
Official Symbol : CALR3
Synonyms : CALR3; calreticulin 3; calreticulin-3; calsperin; cancer/testis antigen 93; CRT2; CT93; FLJ25355; MGC26577; calreticulin-2; CMH19;
Gene ID : 125972
mRNA Refseq : NM_145046
Protein Refseq : NP_659483
MIM : 611414
UniProt ID : Q96L12
Chromosome Location : 19p13.11
Function : calcium ion binding; sugar binding; unfolded protein binding;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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