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Official Full Name calpain 1, (mu/I) large subunit
Background The calpains, calcium-activated neutral proteases, are nonlysosomal, intracellular cysteine proteases. The mammalian calpains include ubiquitous, stomach-specific, and muscle-specific proteins. The ubiquitous enzymes consist of heterodimers with distinct large, catalytic subunits associated with a common small, regulatory subunit. This gene encodes the large subunit of the ubiquitous enzyme, calpain 1. Several transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Nov 2010]
Synonyms CAPN1; calpain 1, (mu/I) large subunit; CANP; muCL; CANP1; CANPL1; muCANP; calpain-1 catalytic subunit; CANP 1; calpain mu-type; micromolar-calpain; calpain-1 large subunit; calpain, large polypeptide L1; calcium-activated neutral proteinase 1; cell proliferation-inducing protein 30; cell proliferation-inducing gene 30 protein;
    • Species :
    • Chicken
    • Human
    • Mouse
    • Pig
    • Rat
    • Rhesus Macaque
    • Source :
    • E.coli
    • HEK293
    • Human
    • Human Erythrocyte
    • Mammalian Cell
    • Porcine Erythrocytes
    • Wheat Germ
    • Tag :
    • GST
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human CAPN1-0355H Recombinant Human CAPN1 Protein, GST-Tagged Wheat Germ GST
    Human CAPN1-10699H Recombinant Human CAPN1, GST-tagged E.coli GST
    Human CAPN1-164H Recombinant Human CAPN1 Mammalian Cell His
    Human CAPN1-27397TH Native Human Calpain-1 Human Erythrocyte N/A
    Human CAPN1-27399TH Recombinant Human CAPN1, His-tagged E.coli His
    Human CAPN1-7865HCL Recombinant Human CAPN1 293 Cell Lysate HEK293 N/A
    Human CAPN1-8448H Native Human CAPN1 Human N/A
    Mouse Capn1-2029M Recombinant Mouse Capn1 protein, His-tagged E.coli His
    Mouse Capn1-2030M Recombinant Mouse Capn1 protein, His-tagged E.coli His
    Mouse CAPN1-2690M Recombinant Mouse CAPN1 Protein Mammalian Cell His
    Rat CAPN1-1118R Recombinant Rat CAPN1 Protein Mammalian Cell His
    Rat Capn1-585R Recombinant Rat Capn1 protein, His-tagged E.coli His
    Rat Capn1-586R Recombinant Rat Capn1 protein, His-tagged E.coli His
    Rhesus Macaque CAPN1-624R Recombinant Rhesus monkey CAPN1 Protein, His-tagged Mammalian Cell His
    Chicken CAPN1-3464C Recombinant Chicken CAPN1 Mammalian Cell His
    Pig CAPN1-186p Native porcine Calpain-1 porcine erythrocytes N/A
    Pig CAPN1-65P Native Porcine Active Porcine Calpain 1 Porcine Erythrocytes N/A
    Kit-0151 CAPN1 Inhibitor (Human) Screening Kit N/A

    capn1 involved in several pathways and played different roles in them. We selected most pathways capn1 participated on our site, such as Protein processing in endoplasmic reticulum, Apoptosis, Alzheimers disease, which may be useful for your reference. Also, other proteins which involved in the same pathway with capn1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Protein processing in endoplasmic reticulum MAPK8B; RPN2; HERPUD1; ATXN3; DNAJB11; ERLEC1; SEC13; P4HB; BAG2; PPP1R15A
    Alzheimers disease ATP5E; COX7B2; Atp5g2; COX8C; CALM1; CDK5R1; BAD; NAE1; ATP5J; NDUFA9

    capn1 has several biochemical functions, for example, calcium ion binding, calcium-dependent cysteine-type endopeptidase activity, cytoskeletal protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by capn1 itself. We selected most functions capn1 had, and list some proteins which have the same functions with capn1. You can find most of the proteins on our site.

    Function Related Protein
    calcium ion binding PCDH18A; CETN4; RYR3; PLCB2; HSP90B1; TNNC2; MMP14; MMP30; PNLIPRP2; FKBP9
    calcium-dependent cysteine-type endopeptidase activity PDCD6; CAPN2L; CAPN2; CAPN9; CAPN1B; CAPN3B; CAPNS1B; CAPN1A; CAPN1; SOLH
    cytoskeletal protein binding EZRB; FLNC; PACSIN3; PACSIN2; FRMD3; NEBL; FABP3; MSNA; RPH3AL; NF2B
    protein binding NMU; MTIF3; RAB25; GTPBP3; ITGA7; EMP1; EXOC4; BASP1; GNB3; CHMP2A

    capn1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with capn1 here. Most of them are supplied by our site. Hope this information will be useful for your research of capn1.


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